PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30370304-5	2018	Treatment with SM or SB was found to significantly reduce the genotoxicity of MMS, upregulate the expression of PTEN and BCL2, and downregulate the expression of BAX and ABL1.	Silymarin	15-17	phosphatase and tensin homolog	Homo sapiens	112-116	
22016029-5	2012	Silymarin also inhibited the phosphorylation of Akt with an increase in expression of phosphatase and tensin homolog (PTEN).	Silymarin	0-9	phosphatase and tensin homolog	Homo sapiens	118-122	
22016029-8	2012	Furthermore, we applied siRNA to lower the PTEN gene, which diminished the anticancer actions of silymarin.	Silymarin	97-106	phosphatase and tensin homolog	Homo sapiens	43-47	
23909904-4	2013	The short interfering RNA (siRNA) is used to confirm the role of phosphatase and tensin homolog (PTEN) in silymarin-induced apoptosis.	Silymarin	106-115	phosphatase and tensin homolog	Homo sapiens	97-101	
23909904-6	2013	Silymarin inhibited the phosphorylation of Akt (over 10-fold) with an increase in expression of PTEN (five to sixfold).	Silymarin	0-9	phosphatase and tensin homolog	Homo sapiens	96-100	
23909904-8	2013	Treatment with siRNA specific to PTEN gene diminished the action of silymarin.	Silymarin	68-77	phosphatase and tensin homolog	Homo sapiens	33-37	
23909904-9	2013	The results suggest that silymarin inhibits the Akt signaling pathway by increasing PTEN expression in FaDu cells and directly affects Bcl-2 family members.	Silymarin	25-34	phosphatase and tensin homolog	Homo sapiens	84-88