PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28071670-0	2017	Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes.	benzyl isothiocyanate	0-21	tumor protein p73	Homo sapiens	127-130	
28071670-4	2017	Mechanistically, BITC induces p73 expression in p53-mutant cells, disrupts the interaction of p73 and mutant-p53, thereby releasing p73 from sequestration and allowing it to be transcriptionally active.	benzyl isothiocyanate	17-21	tumor protein p73	Homo sapiens	30-33	
28071670-4	2017	Mechanistically, BITC induces p73 expression in p53-mutant cells, disrupts the interaction of p73 and mutant-p53, thereby releasing p73 from sequestration and allowing it to be transcriptionally active.	benzyl isothiocyanate	17-21	tumor protein p73	Homo sapiens	94-97	
28071670-4	2017	Mechanistically, BITC induces p73 expression in p53-mutant cells, disrupts the interaction of p73 and mutant-p53, thereby releasing p73 from sequestration and allowing it to be transcriptionally active.	benzyl isothiocyanate	17-21	tumor protein p73	Homo sapiens	94-97	
28071670-5	2017	Furthermore, BITC-induced p53 and p73 axes converge on tumor-suppressor LKB1 which is transcriptionally upregulated by p53 and p73 in p53-wild-type and p53-mutant cells respectively; and in a feed-forward mechanism, LKB1 tethers with p53 and p73 to get recruited to p53-responsive promoters.	benzyl isothiocyanate	13-17	tumor protein p73	Homo sapiens	34-37	
28071670-5	2017	Furthermore, BITC-induced p53 and p73 axes converge on tumor-suppressor LKB1 which is transcriptionally upregulated by p53 and p73 in p53-wild-type and p53-mutant cells respectively; and in a feed-forward mechanism, LKB1 tethers with p53 and p73 to get recruited to p53-responsive promoters.	benzyl isothiocyanate	13-17	tumor protein p73	Homo sapiens	127-130	
28071670-5	2017	Furthermore, BITC-induced p53 and p73 axes converge on tumor-suppressor LKB1 which is transcriptionally upregulated by p53 and p73 in p53-wild-type and p53-mutant cells respectively; and in a feed-forward mechanism, LKB1 tethers with p53 and p73 to get recruited to p53-responsive promoters.	benzyl isothiocyanate	13-17	tumor protein p73	Homo sapiens	127-130