PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23172666-2	2013	In this study, we demonstrate that BITC not only induces apoptosis but also induces autophagy in human hormone-sensitive (Rv1) and -refractory (PC3) prostate cancer cells.	benzyl isothiocyanate	35-39	proprotein convertase subtilisin/kexin type 1	Homo sapiens	144-147	
28423628-2	2017	In this study, we show that BITC effectively suppresses the growth of cultured human prostate cancer cells (CRW-22Rv1 and PC3) by causing mitochondrial membrane potential loss, caspase 3/7 activation and DNA fragmentation.	benzyl isothiocyanate	28-32	proprotein convertase subtilisin/kexin type 1	Homo sapiens	122-125	
23172666-7	2013	However, the increased expression of phospho-mTOR (Ser2448), phospho-AKT (Ser473) and antiapoptotic Bcl-2 were detected only in PC3 cells at later stages of BITC treatment.	benzyl isothiocyanate	157-161	proprotein convertase subtilisin/kexin type 1	Homo sapiens	128-131	
23172666-9	2013	Activation of the AKT survival pathway was only observed in PC3 cells, representing a resistance mechanism of advanced prostate cancer upon BITC treatment.	benzyl isothiocyanate	140-144	proprotein convertase subtilisin/kexin type 1	Homo sapiens	60-63