PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30099761-0 2019 Upregulation of C/EBPbeta and TSC2 by an HDAC inhibitor CG200745 protects heart from DOCA-induced hypertrophy. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 56-64 CCAAT/enhancer binding protein beta Rattus norvegicus 16-25 30099761-5 2019 We hypothesized that an HDAC inhibitor, CG200745 (CG), ameliorates cardiac hypertrophy through the inhibition of mTORC1 signaling by upregulating of the CCAAT/enhancer-binding protein-beta (C/EBP-beta)/TSC2 pathway. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 40-48 CCAAT/enhancer binding protein beta Rattus norvegicus 153-188 30099761-5 2019 We hypothesized that an HDAC inhibitor, CG200745 (CG), ameliorates cardiac hypertrophy through the inhibition of mTORC1 signaling by upregulating of the CCAAT/enhancer-binding protein-beta (C/EBP-beta)/TSC2 pathway. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 40-48 CCAAT/enhancer binding protein beta Rattus norvegicus 190-200 30099761-5 2019 We hypothesized that an HDAC inhibitor, CG200745 (CG), ameliorates cardiac hypertrophy through the inhibition of mTORC1 signaling by upregulating of the CCAAT/enhancer-binding protein-beta (C/EBP-beta)/TSC2 pathway. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 40-42 CCAAT/enhancer binding protein beta Rattus norvegicus 153-188 30099761-5 2019 We hypothesized that an HDAC inhibitor, CG200745 (CG), ameliorates cardiac hypertrophy through the inhibition of mTORC1 signaling by upregulating of the CCAAT/enhancer-binding protein-beta (C/EBP-beta)/TSC2 pathway. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 40-42 CCAAT/enhancer binding protein beta Rattus norvegicus 190-200 30099761-12 2019 In addition, CG treated rats showed an increased in the expression and acetylation of C/EBP-beta, owing to the increase in the recruitment of C/EBP-beta and Pol II at Tsc2 gene promoter. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 13-15 CCAAT/enhancer binding protein beta Rattus norvegicus 86-96 30099761-12 2019 In addition, CG treated rats showed an increased in the expression and acetylation of C/EBP-beta, owing to the increase in the recruitment of C/EBP-beta and Pol II at Tsc2 gene promoter. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 13-15 CCAAT/enhancer binding protein beta Rattus norvegicus 142-152 30099761-13 2019 Thus, CG ameliorates cardiac hypertrophy through the inhibition of mTORC1 signaling via upregulation of the C/EBP-beta/TSC2 pathway in DOCA-induced hypertensive rats. N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide 6-8 CCAAT/enhancer binding protein beta Rattus norvegicus 108-118