PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10976913-7	2000	Consistent with the effects on STAT5B phosphorylation, tyrosine-to-phenylalanine mutation of tyrosine 595 prolongs the duration of tyrosyl phosphorylation of GHR and JAK2.	cyclo(tyrosyl-tyrosyl)	131-138	Janus kinase 2	Rattus norvegicus	166-170	
9886807-8	1999	The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1.	cyclo(tyrosyl-tyrosyl)	29-36	Janus kinase 2	Rattus norvegicus	24-28	
9886807-8	1999	The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1.	cyclo(tyrosyl-tyrosyl)	29-36	Janus kinase 2	Rattus norvegicus	209-213	
9886807-8	1999	The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1.	cyclo(tyrosyl-tyrosyl)	63-70	Janus kinase 2	Rattus norvegicus	24-28	
9886807-8	1999	The correlation between JAK2 tyrosyl phosphorylation and IRS-1 tyrosyl phosphorylation in response to GH together with the results of the in vitro tyrosine kinase assay are consistent with the hypothesis that JAK2 may mediate GH-induced phosphorylation of IRS-1.	cyclo(tyrosyl-tyrosyl)	63-70	Janus kinase 2	Rattus norvegicus	209-213	
7545168-2	1995	Although the receptor for growth hormone (GH) does not contain intrinsic tyrosine kinase activity, GH has recently been shown to promote the association of its receptor with JAK2 tyrosine kinase, to activate JAK2, and to promote the tyrosyl phosphorylation of both GH receptor (GHR) and JAK2.	cyclo(tyrosyl-tyrosyl)	233-240	Janus kinase 2	Rattus norvegicus	174-178	
7545168-6	1995	Consistent with Tyr333 and/or Tyr338 serving as substrates of JAK2, these substitutions resulted in a loss of tyrosyl phosphorylation of truncated receptor in an in vitro kinase assay using substantially purified GH.GHR.JAK2 complexes.	cyclo(tyrosyl-tyrosyl)	110-117	Janus kinase 2	Rattus norvegicus	62-66	
8063815-6	1994	In studies performed in CHO and RIN-5AH cells, the ability of JAK2 to associate with the mutated GHR was found to correlate with GH-dependent activation of JAK2, tyrosyl phosphorylation of GHR (in the case of GHR1-638 and GHR1-454), and the ability of the GHR to copurify with tyrosine kinase activity.	cyclo(tyrosyl-tyrosyl)	162-169	Janus kinase 2	Rattus norvegicus	62-66