PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10780998-8	2000	COX-2 protein was weakly induced by SPNO in basal conditions and in the presence of LPS a synergy for HO-1 and COX-2 protein expression was observed.	spermine nitric oxide complex	36-40	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	0-5	
10780998-8	2000	COX-2 protein was weakly induced by SPNO in basal conditions and in the presence of LPS a synergy for HO-1 and COX-2 protein expression was observed.	spermine nitric oxide complex	36-40	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	111-116	
10780998-10	2000	Our results indicate that reactive oxygen species participate in the inductive effect of NO donors or LPS on HO-1 expression, whereas endogenous NO production may play a role in the mechanism of the synergy exhibited by SPNO and LPS on HO-1 and COX-2 expression.	spermine nitric oxide complex	220-224	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	245-250	
15879708-4	2005	When extracellular pH ([pH]o) was reduced to pH 6.4, COX-2 mRNA increased, with a peak at 2 h. This was blocked by pretreatment with actinomycin D and incubation with spermine NONOate (SPER/NO, a nitric oxide donor).	spermine nitric oxide complex	167-183	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	53-58