1 | 675837 | Small-scale trials of six drugs against Onchocerca volvulus. | Tropenmed Parasitol | 1978 Jun |
2 |
2 | 3808054 | Platelets mediate the action of diethylcarbamazine on microfilariae. | Nature | 1987 Feb 5-11 |
2 |
3 | 4017101 | Phosphate buffer and salt medium concentrations affect the inactivation of T4 phage by platinum(II) complexes. | Chem Biol Interact | 1985 Jun |
5 |
4 | 7630209 | Bleeding and thromboembolism during anticoagulant therapy: a population-based study in Rochester, Minnesota. | Mayo Clin Proc | 1995 Aug |
1 |
5 | 9256433 | P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. | Proc Natl Acad Sci U S A | 1997 Aug 19 |
6 |
6 | 9259288 | Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. | Hum Mol Genet | 1997 Aug |
2 |
7 | 9399897 | Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis. | Am J Hum Genet | 1997 Dec |
1 |
8 | 9467947 | Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines. | Oncogene | 1998 Jan 8 |
4 |
9 | 9510470 | Infrequent mutations in the PTEN/MMAC1 gene among primary breast cancers. | Jpn J Cancer Res | 1998 Jan |
2 |
10 | 9560261 | Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. | Proc Natl Acad Sci U S A | 1998 Apr 28 |
2 |
11 | 9593664 | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. | J Biol Chem | 1998 May 29 |
9 |
12 | 9616126 | Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. | Science | 1998 Jun 5 |
1 |
13 | 9622068 | Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. | Cancer Res | 1998 Jun 1 |
2 |
14 | 9796706 | Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression. | Oncogene | 1998 Oct 1 |
2 |
15 | 9797362 | Mutational abrogation of the PTEN/MMAC1 gene in gastrointestinal polyps in patients with Cowden disease. | Gastroenterology | 1998 Nov |
1 |
16 | 9811831 | The lipid phosphatase activity of PTEN is critical for its tumor supressor function. | Proc Natl Acad Sci U S A | 1998 Nov 10 |
4 |
17 | 9823298 | The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. | Cancer Res | 1998 Nov 15 |
1 |
18 | 9860981 | PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. | Proc Natl Acad Sci U S A | 1998 Dec 22 |
1 |
19 | 9865719 | The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. | Cancer Res | 1998 Dec 15 |
3 |
20 | 9885576 | The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. | Mol Cell | 1998 Dec |
5 |
21 | 9927060 | Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. | Cancer Res | 1999 Jan 15 |
2 |
22 | 9931326 | PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies. | Hum Mol Genet | 1999 Feb |
5 |
23 | 10022807 | Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase. | Oncogene | 1999 Feb 11 |
1 |
24 | 10051603 | Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. | Proc Natl Acad Sci U S A | 1999 Mar 2 |
5 |
25 | 10188904 | Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas. | Br J Cancer | 1999 Mar |
2 |
26 | 10200246 | New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. | Proc Natl Acad Sci U S A | 1999 Apr 13 |
1 |
27 | 10203785 | PTEN: a tumour suppressor that functions as a phospholipid phosphatase. | Trends Cell Biol | 1999 Apr |
2 |
28 | 10209098 | Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN. | Curr Biol | 1999 Mar 25 |
3 |
29 | 10209156 | Signalling through phosphoinositide 3-kinases: the lipids take centre stage. | Curr Opin Cell Biol | 1999 Apr |
2 |
30 | 10377431 | The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway. | Proc Natl Acad Sci U S A | 1999 Jun 22 |
1 |
31 | 10400703 | PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway. | J Biol Chem | 1999 Jul 16 |
3 |
32 | 10400993 | PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. | Hum Mol Genet | 1999 Aug |
1 |
33 | 10415336 | PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation. | Gene | 1999 Jul 22 |
2 |
34 | 10417424 | [PTEN: a tumor suppressor with original properties]. | Bull Cancer | 1999 Jun |
5 |
35 | 10469123 | PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis. | Eur J Biochem | 1999 Aug |
4 |
36 | 10485448 | Alterations of the PPP1R3 gene in human cancer. | Cancer Res | 1999 Sep 1 |
1 |
37 | 10485474 | Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. | Cancer Res | 1999 Sep 1 |
1 |
38 | 10503872 | Somatic mutation of the PTEN/MMAC1 gene in breast cancers with microsatellite instability. | Cancer Lett | 1999 Sep 20 |
2 |
39 | 10547389 | PTEN gene and integrin signaling in cancer. | J Natl Cancer Inst | 1999 Nov 3 |
1 |
40 | 10554022 | The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells. | Cancer Res | 1999 Nov 1 |
3 |
41 | 10555148 | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. | Cell | 1999 Oct 29 |
3 |
42 | 10564676 | Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. | J Natl Cancer Inst | 1999 Nov 17 |
8 |
43 | 10582703 | PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. | Cancer Res | 1999 Nov 15 |
1 |
44 | 10597304 | The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. | Oncogene | 1999 Nov 25 |
1 |
45 | 10617573 | Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. | Genes Dev | 1999 Dec 15 |
2 |
46 | 10644997 | The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity. | Oncogene | 2000 Jan 13 |
1 |
47 | 10646847 | Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding. | Cancer Res | 2000 Jan 1 |
4 |
48 | 10648629 | A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling. | Mol Cell Biol | 2000 Feb |
1 |
49 | 10657643 | The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase. | J Immunol | 2000 Feb 15 |
1 |
50 | 10698513 | Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene. | Oncogene | 2000 Feb 3 |
6 |