protein tyrosine phosphatase, non-receptor type 1 ; Rattus norvegicus






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1 1736296 Isolation of a src homology 2-containing tyrosine phosphatase. Proc Natl Acad Sci U S A 1992 Feb 1 1
2 2006602 Toxic oxygen metabolites induce vasoconstriction and bronchoconstriction in isolated, plasma-perfused rat lungs. Acta Anaesthesiol Scand 1991 Jan 2
3 2057135 Anticonvulsants do not suppress long-term potentiation (LTP) in the rat hippocampus. Neurosci Lett 1991 Jan 14 1
4 2898342 Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes. Drug Metab Dispos 1988 Mar-Apr 2
5 7544790 Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway. J Biol Chem 1995 Sep 1 1
6 7693694 Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B. J Biol Chem 1993 Nov 5 4
7 8914924 Inhibition of a Src homology 2 domain containing protein tyrosine phosphatase by vanadate in the primary culture of hepatocytes. Arch Biochem Biophys 1996 Nov 15 7
8 9065475 Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. J Biol Chem 1997 Mar 21 1
9 9415395 Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen). Mol Endocrinol 1997 Dec 4
10 9418872 Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand. Mol Cell Biol 1998 Jan 2
11 9443918 Protein tyrosine phosphatase 1B negatively regulates integrin signaling. Curr Biol 1998 Jan 29 3
12 9490073 Purification and preliminary characterization of an Fc epsilon-receptor-activated protein-tyrosine phosphatase from mast cells. Eur J Biochem 1998 Feb 1 3
13 9801817 Potent non-peptidyl inhibitors of protein tyrosine phosphatase 1B. Bioorg Med Chem 1998 Sep 6
14 9826659 Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of rat-1 fibroblasts and promotes differentiation of K562 cells. Proc Natl Acad Sci U S A 1998 Nov 24 2
15 9887114 Elastic moduli of excised constricted rat lungs. J Appl Physiol (1985) 1999 Jan 1
16 10409197 Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins. Am J Physiol 1999 Jul 2
17 10462031 Phosphatase activity in the arterial wall after balloon injury: effect of somatostatin analog octreotide. Lab Invest 1999 Aug 4
18 10787405 Protein-tyrosine phosphatase reduces the number of apical small conductance K+ channels in the rat cortical collecting duct. J Biol Chem 2000 Jul 7 5
19 10841942 Comparison of signaling pathways involved in apoptosis of a thymocyte hybridoma triggered by a rat thymic medullary epithelial cell line, dexamethasone or T-cell receptor cross-linking. Immunol Lett 2000 May 1 1
20 11038828 [Free fatty acids promoting PTP1B expression in rat skeletal muscle and hepatic cells]. Zhonghua Yi Xue Za Zhi 1998 Oct 1
21 11101193 Effect of vanadate and insulin on glucose transport in isolated adult rat cardiomyocytes. Cardiovasc Drugs Ther 2000 Oct 2
22 11134617 N-methyl-D-aspartate receptor activation results in regulation of extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apototic-like death. Brain Res 2000 Dec 29 2
23 11136729 Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells. J Biol Chem 2001 Mar 30 2
24 11147799 Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes. Diabetes 2001 Jan 1
25 11162564 C-peptide attenuates protein tyrosine phosphatase activity and enhances glycogen synthesis in L6 myoblasts. Biochem Biophys Res Commun 2001 Jan 26 1
26 11169624 PTP1B regulates neurite extension mediated by cell-cell and cell-matrix adhesion molecules. J Neurosci Res 2001 Jan 15 1
27 11236902 TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells. Shock 2001 Mar 1
28 11350745 Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases. Am J Physiol Cell Physiol 2001 Jun 1
29 11463798 Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4). J Biol Chem 2001 Sep 21 1
30 11703427 Effects of adenovirus-mediated liver-selective overexpression of protein tyrosine phosphatase-1b on insulin sensitivity in vivo. Diabetes Obes Metab 2001 Oct 2
31 11855663 Insulin in combination with vanadate stimulates glucose transport in isolated cardiomyocytes from obese Zucker rats. Cardiovasc Drugs Ther 2001 Sep 4
32 11866457 Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats. Biochem Biophys Res Commun 2002 Mar 8 1
33 11936837 Bis(maltolato)oxovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo. Mol Cell Biochem 2002 Jan 7
34 12365558 Troglitazone ameliorates abnormal activity of protein tyrosine phosphatase in adipose tissues of Otsuka Long-Evans Tokushima Fatty rats. Tohoku J Exp Med 2002 Jul 1
35 12384979 K vitamins, PTP antagonism, and cell growth arrest. J Cell Physiol 2002 Dec 2
36 12435803 Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease. Mol Pharmacol 2002 Dec 6
37 12747781 Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. J Med Chem 2003 May 22 5
38 12790802 Identification of hepatic transcriptional changes in insulin-resistant rats treated with peroxisome proliferator activated receptor-alpha agonists. J Mol Endocrinol 2003 Jun 6
39 12902327 Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts. J Biol Chem 2003 Oct 17 2
40 12920200 Adenosine-A2a receptor down-regulates cerebral smooth muscle L-type Ca2+ channel activity via protein tyrosine phosphatase, not cAMP-dependent protein kinase. Mol Pharmacol 2003 Sep 4
41 12941932 Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression. J Biol Chem 2003 Oct 31 3
42 15209419 The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons. Neurochem Int 2004 Jun 6
43 15271661 Increase of PTP levels in vascular injury and in cultured aortic smooth muscle cells treated with specific growth factors. Am J Physiol Heart Circ Physiol 2004 Nov 3
44 15454854 A protein tyrosine phosphatase inhibitor accelerates angiogenesis in a rat model of hindlimb ischemia. J Cardiovasc Pharmacol 2004 Oct 2
45 15465928 The protein kinase C inhibitor Go6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor. Mol Pharmacol 2005 Jan 5
46 15734724 A nonspecific phosphotyrosine phosphatase inhibitor, bis(maltolato)oxovanadium(IV), improves glucose tolerance and prevents diabetes in Zucker diabetic fatty rats. Exp Biol Med (Maywood) 2005 Mar 1
47 15870954 Ethanol inhibits insulin expression and actions in the developing brain. Cell Mol Life Sci 2005 May 1
48 15889998 Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases. Antioxid Redox Signal 2005 May-Jun 9
49 15997237 Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats. Br J Pharmacol 2005 Sep 4
50 16043163 Involvement of BKCa alpha subunit tyrosine phosphorylation in vascular hyporesponsiveness of superior mesenteric artery following hemorrhagic shock in rats. Cardiovasc Res 2005 Nov 1 6