xenotropic and polytropic retrovirus receptor 1 ; Homo sapiens






419 Article(s)
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1 3133433 Multidisciplinary treatment for resectable pancreatic cancer. Int J Pancreatol 1988 May 1
2 6751026 Antihypertensive effects at rest and during exercise of a calcium blocker, nifedipine, alone and in combination with metoprolol. Acta Med Scand 1982 1
3 7583541 Retinoids stimulate fibrinogen production both in vitro (hepatocytes) and in vivo. Induction requires activation of the retinoid X receptor. Arterioscler Thromb Vasc Biol 1995 Oct 1
4 8625436 Convergence of three steroid receptor pathways in the mediation of nongenotoxic hepatocarcinogenesis. Carcinogenesis 1996 Feb 1
5 8723391 Human nuclear receptor heterodimers: opportunities for detecting targets of transcriptional regulation using yeast. Gene Expr 1996 2
6 9927670 Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses. Proc Natl Acad Sci U S A 1999 Feb 2 1
7 10334992 Identification of a nuclear receptor for bile acids. Science 1999 May 21 1
8 10334993 Bile acids: natural ligands for an orphan nuclear receptor. Science 1999 May 21 3
9 10673288 Bile acids are physiological ligands for a nuclear receptor. Gut 2000 Mar 1
10 10753890 Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription. J Biol Chem 2000 Apr 14 2
11 10884298 Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts. J Lipid Res 2000 Jul 1
12 10995004 Oral 9-cis retinoic acid (Alitretinoin) in the treatment of myelodysplastic syndromes: results from a pilot study. Leukemia 2000 Sep 2
13 11030332 A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 2000 Sep 2
14 11045902 Pharmacophore/receptor models for GABA(A)/BzR alpha2beta3gamma2, alpha3beta3gamma2 and alpha4beta3gamma2 recombinant subtypes. Included volume analysis and comparison to alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2 subtypes. Drug Des Discov 2000 1
15 11114187 Identification of XPR-1, a progesterone receptor required for Xenopus oocyte activation. Proc Natl Acad Sci U S A 2000 Dec 19 3
16 11150726 FXR, a bile acid receptor and biological sensor. Trends Cardiovasc Med 2000 Jan 1
17 11387316 Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J Biol Chem 2001 Aug 3 2
18 11533040 Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor. J Biol Chem 2001 Nov 9 3
19 11870371 Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump. Hepatology 2002 Mar 3
20 11907135 Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP. J Lipid Res 2002 Apr 1
21 12015815 Identification of two highly sialylated human tear-fluid DMBT1 isoforms: the major high-molecular-mass glycoproteins in human tears. Biochem J 2002 Sep 1 3
22 12019969 Solvation of copper ions by acetone. structures and sequential binding energies of Cu+(acetone)x, x = 1-4 from collision-induced dissociation and theoretical studies. J Am Soc Mass Spectrom 2002 May 2
23 12052824 Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. J Biol Chem 2002 Aug 30 1
24 12149270 Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA. J Biol Chem 2002 Oct 4 2
25 12202460 Bile acid regulation of gene expression: roles of nuclear hormone receptors. Endocr Rev 2002 Aug 2
26 12485937 GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells. Blood 2003 Jan 1 1
27 12525500 Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. J Biol Chem 2003 Mar 21 1
28 12554753 Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor. Mol Endocrinol 2003 Feb 1
29 12559450 The coming of age of our understanding of the enterohepatic circulation of bile salts. Am J Surg 2003 Feb 8
30 12693042 Chlorine oxide radicals ClOx (x = 1-4) studied by matrix isolation spectroscopy. Chemistry 2002 Dec 16 1
31 12704471 The role of the enterohepatic circulation of bile salts and nuclear hormone receptors in the regulation of cholesterol homeostasis: Bile salts as ligands for nuclear hormone receptors. Can J Gastroenterol 2003 Apr 16
32 12705905 Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene. Biochem Biophys Res Commun 2003 Apr 25 2
33 12718871 Nuclear receptor ligands and cofactor recruitment: is there a coactivator "on deck"? Mol Cell 2003 Apr 1
34 12718892 A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Mol Cell 2003 Apr 3
35 12749886 Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR). Bioorg Med Chem Lett 2003 Jun 2 2
36 12761213 Human kininogen gene is transactivated by the farnesoid X receptor. J Biol Chem 2003 Aug 1 1
37 12846418 Effect of ligands of nuclear hormone receptors on sodium/iodide symporter expression and activity in breast cancer cells. Breast Cancer Res Treat 2003 Jun 3
38 13130122 Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation. J Lipid Res 2004 Jan 3
39 14684751 The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion. J Biol Chem 2004 Mar 5 1
40 14733360 Ligand-binding domain of farnesoid X receptor (FXR) had the highest sensitivity and activity among FXR variants in a fluorescence-based assay. Lipids 2003 Nov 2
41 14872321 Hydrogen bonding interactions in E- or Z-2-phenyl-3-( X'-pyridyl)propenoic acid ( X=2, 3 or 4) assemblies--a molecular modeling study. J Mol Model 2004 Apr 3
42 14992012 [On the bile acid receptor FXR]. Sheng Li Ke Xue Jin Zhan 2003 Oct 2
43 14996618 Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential. Expert Opin Ther Targets 2004 Feb 3
44 15145977 Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor. J Lipid Res 2004 Aug 4
45 15147890 The farnesoid X receptor induces very low density lipoprotein receptor gene expression. FEBS Lett 2004 May 21 1
46 15187081 Identification of DRIP205 as a coactivator for the Farnesoid X receptor. J Biol Chem 2004 Aug 27 3
47 15198932 Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. Am J Physiol Endocrinol Metab 2004 Oct 2
48 15243520 Comparison of selective retinoic acid receptor- and retinoic X receptor-mediated efficacy, tolerance, and survival in cutaneous t-cell lymphoma. J Am Acad Dermatol 2004 Jul 1
49 15307955 Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets. DNA Cell Biol 2004 Aug 3
50 15317466 Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid. J Med Chem 2004 Aug 26 2