caspase 3 ; Mus musculus






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1 6307139 Broad-spectrum antiviral activity of the carbocyclic analog of 3-deazaadenosine. Antiviral Res 1983 Mar 5
2 8614469 Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 1996 Apr 25 2
3 8920897 Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J Exp Med 1996 Nov 1 2
4 8948030 Hydroquinone, a bioreactive metabolite of benzene, inhibits apoptosis in myeloblasts. Stem Cells 1996 Nov 2
5 8976202 Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. J Exp Med 1996 Dec 1 4
6 8987778 Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J Neurosci 1997 Jan 15 3
7 8991541 Inhibition of enriched stem cells in vivo and in vitro by the hemoregulatory peptide SK&F108636. Stem Cells 1996 Mar 4
8 9036942 Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones. J Immunol 1997 Mar 1 3
9 9070890 Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF. Biochem Biophys Res Commun 1997 Feb 24 1
10 9184074 Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling. Exp Cell Res 1997 May 25 4
11 9247143 Bcl-2 protein inhibits oxysterol-induced apoptosis through suppressing CPP32-mediated pathway. FEBS Lett 1997 Jul 7 2
12 9348308 Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus. J Exp Med 1997 Nov 3 1
13 9500454 Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment. Cancer Res 1998 Mar 1 1
14 9519815 Distinct interleukin-1beta-converting enzyme family proteases mediate cisplatin- and staurosporine-induced apoptosis of mouse proximal tubule cells. Life Sci 1998 1
15 9521092 The dominant role of CPP32 subfamily in fas-mediated hepatitis. Proc Soc Exp Biol Med 1998 Apr 4
16 9531309 Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model. J Immunol 1998 Apr 1 5
17 9535810 Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells. Biochem Biophys Res Commun 1998 Apr 7 2
18 9551718 Necessity of interleukin-1beta converting enzyme cascade in taxotere-initiated death signaling. Eur J Pharmacol 1998 Feb 5 2
19 9556551 Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J Biol Chem 1998 May 1 1
20 9570797 Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 1998 May 15 10
21 9605752 Induction of apoptosis and activation of interleukin 1beta-converting enzyme/Ced-3 protease (caspase-3) and c-Jun NH2-terminal kinase 1 by benzo(a)pyrene. Cancer Res 1998 May 15 7
22 9692710 Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons. Neuroscience 1998 Oct 9
23 9705090 Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation. Mol Cell Endocrinol 1998 Apr 30 1
24 9737957 c-Fos degradation by the proteasome. An early, Bcl-2-regulated step in apoptosis. J Biol Chem 1998 Sep 25 2
25 9774436 A relationship between 5-lipoxygenase-activating protein and bcl-xL expression in murine pro-B lymphocytic FL5.12 cells. J Biol Chem 1998 Oct 23 3
26 9787177 Resistance to cytotoxic chemotherapy induced by CD40 ligand in lymphoma cells. Blood 1998 Nov 1 1
27 9792795 Redistribution of Bax from cytosol to membranes is induced by apoptotic stimuli and is an early step in the apoptotic pathway. Biochem Biophys Res Commun 1998 Oct 20 1
28 9795219 Neuronal apoptosis induced by histone deacetylase inhibitors. Brain Res Mol Brain Res 1998 Oct 30 1
29 9811849 Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo. Proc Natl Acad Sci U S A 1998 Nov 10 2
30 9811886 Impaired liver regeneration in inducible nitric oxide synthasedeficient mice. Proc Natl Acad Sci U S A 1998 Nov 10 1
31 9821861 The formation of ceramide from sphingomyelin is associated with cellular apoptosis. Acta Biochim Pol 1998 11
32 9917313 Discorhabdin P, a new enzyme inhibitor from a deep-water Caribbean sponge of the genus Batzella. J Nat Prod 1999 Jan 1
33 10078546 Essential role of caspase-3 in apoptosis of mouse beta-cells transfected with human Fas. Diabetes 1999 Mar 5
34 10189893 Differential induction of apoptosis in B16 melanoma and EL-4 lymphoma cells by cytostatin and bactobolin. Jpn J Cancer Res 1999 Feb 1
35 10194182 LPS challenge in D-galactosamine-sensitized mice accounts for caspase-dependent fulminant hepatitis, not for septic shock. Am J Respir Crit Care Med 1999 Apr 1
36 10200514 Teratogen-induced cell death in postimplantation mouse embryos: differential tissue sensitivity and hallmarks of apoptosis. Cell Death Differ 1998 Jul 2
37 10200549 Apoptosis in hematopoietic cells (FL5.12) caused by interleukin-3 withdrawal: relationship to caspase activity and the loss of glutathione. Cell Death Differ 1999 Jan 3
38 10224123 Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor. J Biol Chem 1999 May 7 2
39 10321830 Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity. J Cell Biochem 1999 Jun 1 2
40 10361889 The protective effect of cyclosporine A on anti-Fas antibody-induced hepatitis in mice. Jpn J Pharmacol 1999 Apr 3
41 10363899 Caspase-3-dependent organ apoptosis early after burn injury. Ann Surg 1999 Jun 1
42 10378898 A novel stromal cell-dependent hematopoietic cell line established from temperature-sensitive SV40 T-antigen transgenic mice. Exp Hematol 1999 Jun 1
43 10381555 Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment. Brain Res Mol Brain Res 1999 Jun 18 2
44 10385654 CD95-Mediated murine hepatic apoptosis requires an intact glutathione status. Hepatology 1999 Jul 4
45 10435092 Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase. Gene Ther 1999 Mar 2
46 10442630 Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli. Oncogene 1999 Aug 5 1
47 10463952 Overexpression of manganese superoxide dismutase protects against mitochondrial-initiated poly(ADP-ribose) polymerase-mediated cell death. FASEB J 1999 Sep 1
48 10464143 Interleukin 1beta protects mice from Fas-mediated hepatocyte apoptosis and death. Gastroenterology 1999 Sep 1
49 10479344 Secobatzellines A and B, two new enzyme inhibitors from a deep-water Caribbean sponge of the genus Batzella. J Nat Prod 1999 Aug 1
50 10518582 Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene. Proc Natl Acad Sci U S A 1999 Oct 12 1