cytochrome P450 1A2 ; Oryctolagus cuniculus






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1 187601 Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. J Biol Chem 1976 Dec 25 5
2 277915 Regio- and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA. Proc Natl Acad Sci U S A 1978 Jul 8
3 1060073 Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver. Proc Natl Acad Sci U S A 1975 Oct 2
4 1123353 Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. J Biol Chem 1975 May 10 1
5 1567227 Characterization of the rabbit CYP1A1 and CYP1A2 genes: developmental and dioxin-inducible expression of rabbit liver P4501A1 and P4501A2. Arch Biochem Biophys 1992 May 1 4
6 2015817 Developmental expression of rabbit cytochrome P450 CYP1A1, CYP1A2 and CYP3A6 genes. Effect of weaning and rifampicin. Eur J Biochem 1991 Apr 10 1
7 2515665 Studies on covalent binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to cytochromes P-450 LM2 and LM4 and NADPH-cytochrome P-450 reductase. Xenobiotica 1989 Dec 11
8 2847925 cDNA cloning and functional expression in yeast Saccharomyces cerevisiae of beta-naphthoflavone-induced rabbit liver P-450 LM4 and LM6. Eur J Biochem 1988 Nov 1 1
9 2991917 Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible rabbit mRNAs for cytochrome P-450 isozymes 4 and 6. Proc Natl Acad Sci U S A 1985 Aug 1
10 3113479 Zwitterionic detergent mediated interaction of purified cytochrome P-450LM4 from 5,6-benzoflavone-treated rabbits with MADPH-cytochrome P-450 reductase. Biochemistry 1987 Apr 21 7
11 3120780 Chemical modification of cytochrome P-450 LM4. Identification of functionally linked tyrosine residues. Biochim Biophys Acta 1987 Dec 18 3
12 3202847 Comparative studies on the accessibility and functional importance of tyrosine residues in cytochrome P-450 isozymes. Biomed Biochim Acta 1988 8
13 3418515 Pyridine induction of cytochrome P-450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation. J Pharmacol Exp Ther 1988 Sep 2
14 3963817 The effect of substrate on the expression of activity catalyzed by cytochrome P-450: metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems. Arch Biochem Biophys 1986 Apr 1
15 6270135 Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. J Biol Chem 1981 Nov 10 4
16 6407528 A form of rabbit liver cytochrome P-450 that catalyzes the 7 alpha-hydroxylation of cholesterol. Biochim Biophys Acta 1983 Feb 7 6
17 6511797 On the mechanism of action of cytochrome P-450. Oxidation and reduction of the ferrous dioxygen complex of liver microsomal cytochrome P-450 by cytochrome b5. J Biol Chem 1984 Dec 25 2
18 6589592 On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes. Proc Natl Acad Sci U S A 1984 Jul 1
19 6654907 Binding of cholesterol to cytochromes P-450 from rabbit liver microsomes. J Biol Chem 1983 Dec 25 9
20 6773567 Incorporation of purified components of the rabbit liver microsomal hydroxylase system into phospholipid vesicles. Biochim Biophys Acta 1980 Jul 1
21 6797484 [Immunochemical study of catalytic activity of cytochrome P-450-LM4 from rabbit liver microsomes]. Biokhimiia 1981 Dec 2
22 6811268 Hydroxylations in biosynthesis of bile acids. Cytochrome P-450 LM4 and 12alpha-hydroxylation of 5beta-cholestane-3alpha, 7alpha-diol. Eur J Biochem 1982 Jul 1
23 6811587 Hydroxylations in biosynthesis of bile acids. Isolation of subfractions with different substrate specificity from cytochrome P-450LM4. J Biol Chem 1982 Oct 10 18
24 6813677 Monoclonal antibodies to rabbit liver cytochrome P-450LM2 and cytochrome P-450LM4. Mol Pharmacol 1982 Jan 1
25 6816232 Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes. Biochem Biophys Res Commun 1982 Sep 16 1
26 6833228 Kinetics and mechanism of CO binding to cytochromes P-450LM2 and P-450LM4. Effect of phospholipid, nonionic detergent, and substrate binding. J Biol Chem 1983 Mar 25 1
27 6889595 Hydroxylation of prostaglandins by inducible isozymes of rabbit liver microsomal cytochrome P-450. Participation of cytochrome b5. J Biol Chem 1982 Oct 10 3
28 7061465 Heme ligand replacement reactions of cytochrome P-450. Characterization of the bonding atom of the axial ligand trans to thiolate as oxygen. J Biol Chem 1982 Mar 25 3
29 7308218 Cytochromes P-450 LM3b and LM4 in biosynthesis of bile acids. Eur J Biochem 1981 Nov 2
30 7336952 Regio-selectivity of purified forms of rabbit liver microsomal cytochrome P-450 in the metabolism of benzo(a)pyrene, n-hexane and 7-ethoxyresorufin. Acta Pharmacol Toxicol (Copenh) 1981 May 10
31 7944401 Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process. Arch Biochem Biophys 1994 Oct 2
32 8315282 Ontogenetic development of the distribution of constitutive and 3-methylcholanthrene-induced CYP1A1 and CYP1A2 in rabbit liver. J Histochem Cytochem 1993 Jun 5
33 8561506 Substrate influence on interaction between cytochrome P450 and cytochrome b5 in microsomes. Arch Biochem Biophys 1996 Jan 15 3
34 8607843 Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultured rabbit hepatocytes. Biochem Biophys Res Commun 1996 Mar 27 1
35 8631144 Developmental changes in hepatic activation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in rabbit. Carcinogenesis 1996 Mar 3
36 8670218 Preparation, purification, and spectrophotometric characterization of cytochrome P450 1A2 conjugated with polyethylene glycol monomethyl ether. Biochem Biophys Res Commun 1996 May 15 3
37 8819304 Major involvement of rabbit liver cytochrome P4501A in thiabendazole 5-hydroxylation. Xenobiotica 1996 Jul 2
38 8924611 Reaction of cytochrome P450 with cumene hydroperoxide: ESR spin-trapping evidence for the homolytic scission of the peroxide O-O bond by ferric cytochrome P450 1A2. Chem Res Toxicol 1996 Jan-Feb 2
39 8940137 Conformational change of cytochrome P450 1A2 induced by sodium chloride. J Biol Chem 1996 Dec 6 1
40 9242629 Conformational change of cytochrome P450 1A2 induced by phospholipids and detergents. J Biol Chem 1997 Aug 8 1
41 9737864 Membrane insertion of cytochrome P450 1A2 promoted by anionic phospholipids. Biochemistry 1998 Sep 15 1
42 10950858 Role of reactive oxygen intermediates in the decrease of hepatic cytochrome P450 activity by serum of humans and rabbits with an acute inflammatory reaction. Drug Metab Dispos 2000 Sep 2
43 11042099 Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. Toxicol Appl Pharmacol 2000 Nov 1 3
44 11401574 Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: evidence for two binding sites. Biochemistry 2001 Jun 19 1
45 11717170 Evidence supporting the interaction of CYP2B4 and CYP1A2 in microsomal preparations. Drug Metab Dispos 2001 Dec 3
46 15618705 Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans. Drug Metab Pharmacokinet 2002 4
47 16204464 Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and interleukin 6. Drug Metab Dispos 2006 Jan 2
48 18187423 Cooperativity in oxidation reactions catalyzed by cytochrome P450 1A2: highly cooperative pyrene hydroxylation and multiphasic kinetics of ligand binding. J Biol Chem 2008 Mar 14 1
49 18328798 Cooperativity of cytochrome P450 1A2: interactions of 1,4-phenylene diisocyanide and 1-isopropoxy-4-nitrobenzene. Arch Biochem Biophys 2008 May 1 2
50 21156755 Organization of NADPH-cytochrome P450 reductase and CYP1A2 in the endoplasmic reticulum--microdomain localization affects monooxygenase function. Mol Pharmacol 2011 Mar 3