3-hydroxy-3-methylglutaryl-CoA reductase ; Rattus norvegicus

634 Article(s)
Pub. Date
#Total Relationship(s)
1 14723 [The activity of beta-hydroxy-beta-methylglutaryl-CoA reductase in the soluble fraction of rat liver]. Biokhimiia 1976 Nov 1
2 176160 Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l. J Biol Chem 1976 Mar 25 2
3 187533 [Studies on the regulatory factors of 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase) activity]. Hokkaido Igaku Zasshi 1976 Jul 5
4 190221 Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells. J Biol Chem 1977 Feb 10 1
5 190240 Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat. J Biol Chem 1977 Mar 10 8
6 211173 Cyclic AMP-sensitive activation of hepatic sterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Lipid Res 1978 Aug 3
7 220351 The effect of glucagon, norepinephrine, and dibutyryl cyclic AMP on cholesterol efflux and on the activity of 3-hydroxy-3-methylglutaryl CoA reductase in rat hepatocytes. J Lipid Res 1979 Jan 1
8 241422 Effect of plasma lipoproteins and lecithin-cholesterol dispersions on the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase of isolated rat hepatocytes. Biochim Biophys Acta 1975 Oct 21 3
9 291971 Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proc Natl Acad Sci U S A 1979 Sep 3
10 438654 Improved methods for the solubilization and assay of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Lipid Res 1979 Jan 1
11 438898 Dietary fat-dependent changes in hepatic cholesterogenesis and the activity of 3-hydroxy-3-methylglutaryl-CoA reductase in fasted-refed rats. J Nutr 1979 May 4
12 489551 Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation. J Biol Chem 1979 Oct 10 9
13 489612 Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis. J Biol Chem 1979 Oct 25 4
14 490057 Distribution of 3-hydroxy-3-methylglutaryl coenzyme A reductase and alkaline phosphatase activities in isolated ileal epithelial cells of fed, fasted, cholestyramine-fed, and 4-aminopyrazolo[3,4-d]pyrimidine-treated rats. J Lipid Res 1979 Sep 2
15 620042 Effects of saturated and unsaturated fats given with and without dietary cholesterol on hepatic cholesterol synthesis and hepatic lipid metabolism. Biochim Biophys Acta 1978 Jan 27 1
16 687657 On the mechanism for the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, of cholesterol 7alpha-hydroxylase and of acyl-coenzyme A:cholesterol acyltransferase by free cholesterol. Biochim Biophys Acta 1978 Jul 25 5
17 731132 Influence of cholestyramine on synthesis of cholesterol and bile acids in germfree rats. J Lipid Res 1978 Nov 1
18 737193 Isolation and preliminary characterization of rat liver cells resistant to 7-ketocholesterol. Biochim Biophys Acta 1978 Dec 22 3
19 804475 Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro. An adenine nucleotide-dependent reaction catalyzed by a factor in human fibroblasts. J Biol Chem 1975 Apr 10 4
20 833506 Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol. J Lipid Res 1977 Jan 4
21 856804 Effects of free fatty acids on activity of hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase and on secretion of triglyceride and cholesterol by liver. J Biol Chem 1977 May 10 5
22 857658 Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat. Am J Dig Dis 1977 Apr 1
23 864324 Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7alpha-hydroxylase activities. J Lipid Res 1977 May 3
24 864330 The quantitative assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase: comparison of a thin-layer chromatographic assay with a rapid chloroform extraction assay. J Lipid Res 1977 May 1
25 893399 Purification of 3-hydroxy-3-methylglutaryl coenzyme A reductase by affinity chromatography on blue dextran/Sepharose 4B. Comparison of enzyme purified from normal rats and from rats treated with cholestyramine. J Biol Chem 1977 Sep 10 2
26 923827 A steady state of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured rat liver cells and the increase of its activity by dexamethasone. FEBS Lett 1977 Nov 1 1
27 945302 The regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the isolated perfused rat liver. J Clin Invest 1976 Jun 1
28 965392 Determination of the michaelis-menten constant for beta-hydroxy-beta-methylglutaryl coenzyme A reductase. Demonstration of a substrate affinity 10-fold greater than previously reported. J Biol Chem 1976 Sep 25 1
29 994152 Synthesis and antilipidemic properties of cis-7-chloro-3a, 8b-dihydro-3a-methylfuro[3,4-b]benzofuran-3(1H)-one, a tricyclic clofibrate related lactone having a structural resemblance to mevalonolactone. J Med Chem 1976 Oct 1
30 1036900 The circadian rhythm of synthesis and catabolism of cholesterol. Arch Toxicol 1976 Dec 17 2
31 1066664 Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat. Proc Natl Acad Sci U S A 1976 Aug 5
32 1297647 The role of the transcriptional activator protein DBP in circadian liver gene expression. J Cell Sci Suppl 1992 4
33 1385253 Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats. Gastroenterology 1992 Nov 2
34 1399833 Developmental expression of multiple forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in rat testes. J Androl 1992 Jul-Aug 1
35 1420339 Effects of mevinolin treatment on tissue dolichol and ubiquinone levels in the rat. Biochim Biophys Acta 1992 Nov 11 1
36 1431598 Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat. J Lipid Res 1992 Aug 2
37 1474430 Poloxamer 407-mediated changes in plasma cholesterol and triglycerides following intraperitoneal injection to rats. J Parenter Sci Technol 1992 Nov-Dec 1
38 1483925 Effect of pravastatin, a potent 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on survival of AH130 hepatoma-bearing rats. Jpn J Cancer Res 1992 Nov 1
39 1514609 Is there a role for the adrenals in the development of hypercholesterolemia in Zucker fatty rats? Am J Physiol 1992 Aug 1
40 1521866 Effect of antimicrobials on cholesterol synthesis and content in liver and small intestines. Indian J Exp Biol 1992 Feb 4
41 1544932 Regulation of hepatic sterol metabolism in the rat. Parallel regulation of activity and mRNA for 7 alpha-hydroxylase but not 3-hydroxy-3-methylglutaryl-coenzyme A reductase or low density lipoprotein receptor. J Biol Chem 1992 Mar 15 1
42 1576357 Diabetes-induced alteration of HMGCoA reductase forms in rat livers. Acta Diabetol 1992 1
43 1584203 Preparation of a soluble 58 kDa-3-hydroxy-3-methylglutaryl CoA reductase from liver microsomes and its inhibition by ethoxysilatrane, a hypocholesterolemic compound. Mol Cell Biochem 1992 Mar 25 1
44 1590790 Feedback-type inhibition of activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ubiquinone. Biochem Biophys Res Commun 1992 May 15 2
45 1619360 Bile acid synthesis. VI. Regulation of cholesterol 7 alpha-hydroxylase by taurocholate and mevalonate. J Lipid Res 1992 May 10
46 1645956 Pravastatin, a HMG-CoA reductase inhibitor, blocks the cell cycle progression but not Ca2+ influx induced by IGF-I in FRTL-5 cells. Biochem Biophys Res Commun 1991 May 31 2
47 1742319 Effect of simvastatin on the synthesis and secretion of lipoproteins in relation to the metabolism of cholesterol in cultured hepatocytes. Biochim Biophys Acta 1991 Nov 27 1
48 1765816 Hepatic cholesterol and fatty acid synthesis in pregnant and fetal rats: effect of maternal dietary fat and cholestyramine. J Nutr 1991 Oct 2
49 1776669 Assay of 3-hydroxy-3-methylglutaryl CoA reductase activity using anionic-exchange column chromatography. Anal Biochem 1991 Aug 1 1
50 1780636 Studies on the mechanism of simvastatin-induced thyroid hypertrophy and follicular cell adenoma in the rat. Toxicol Pathol 1991 1