leucyl-tRNA synthetase 2, mitochondrial ; Homo sapiens






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1 15723544 An aminoacyl-tRNA synthetase with a defunct editing site. Biochemistry 2005 Mar 1 1
2 23541342 Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome. Am J Hum Genet 2013 Apr 4 2
3 26322377 Substrate-Assisted and Enzymatic Pretransfer Editing of Nonstandard Amino Acids by Methionyl-tRNA Synthetase. Biochemistry 2015 Sep 22 3
4 27241561 Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one. J Enzyme Inhib Med Chem 2016 2
5 28953378 Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem 2017 Oct 12 3
6 29915081 Error-prone protein synthesis in parasites with the smallest eukaryotic genome. Proc Natl Acad Sci U S A 2018 Jul 3 5
7 30088448 Identification and Characterization of Chemical Compounds that Inhibit Leucyl-tRNA Synthetase from <i>Pseudomonas aeruginosa</i>. Curr Drug Discov Technol 2020 2
8 30737337 Biallelic variants in <i>LARS2</i> and <i>KARS</i> cause deafness and (ovario)leukodystrophy. Neurology 2019 Mar 12 1
9 33221064 Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. Bioorg Med Chem 2021 Jan 1 2
10 35585880 LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells. Oxid Med Cell Longev 2022 3