farnesyl diphosphate synthetase ; Mus musculus






37 Article(s)
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1 8499655 Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene. Mamm Genome 1993 2
2 11581260 Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages. J Biol Chem 2001 Dec 21 2
3 11792566 Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphonates on osteoclast precursors. Bone 2002 Jan 3
4 15084352 Peroxisome proliferator-activated receptor alpha (PPARalpha) activators induce hepatic farnesyl diphosphate synthase gene expression in rodents. J Steroid Biochem Mol Biol 2004 Feb 5
5 16006204 Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo. Bone 2005 Sep 3
6 16165408 Independent pathways in the modulation of osteoclastic resorption by intermediates of the mevalonate biosynthetic pathway: the role of the retinoic acid receptor. Bone 2006 Feb 7
7 16734383 Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases. J Bone Miner Res 2006 May 3
8 17850825 Zoledronic acid-induced IPP/ApppI production in vivo. Life Sci 2007 Sep 8 5
9 18045843 Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells. Development 2008 Jan 2
10 19442620 The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts. Bone 2009 May 1
11 20083572 Overexpression of steroidogenic acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI. Cardiovasc Res 2010 Jun 1 1
12 20641992 <sup>99m</sup>Tc/<sup>188</sup>Re-Labeled dipicolylamine-alendronate 2004 2
13 21184137 Establishment of transgenic mice carrying the gene for farnesyl pyrophosphate synthase. Biotechnol Lett 2011 Apr 2
14 21186792 Small interfering RNA knocks down the molecular target of alendronate, farnesyl pyrophosphate synthase, in osteoclast and osteoblast cultures. Mol Pharm 2011 Aug 1 9
15 21954187 Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis. Mol Nutr Food Res 2011 Sep 1
16 22723339 Transcriptome analysis and in vivo activity of fluvastatin versus zoledronic acid in a murine breast cancer metastasis model. Mol Pharmacol 2012 Sep 1
17 23180723 Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice. Cardiovasc Res 2013 Mar 1 4
18 23277274 Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo. Int J Biochem Cell Biol 2013 Mar 7
19 23564016 A novel inhibitory mechanism of nitrogen-containing bisphosphonate on the activity of Cl- extrusion in osteoclasts. Naunyn Schmiedebergs Arch Pharmacol 2013 Jul 9
20 23935198 Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2. J Immunol 2013 Sep 15 1
21 25688370 Lentiviral-mediated silencing of farnesyl pyrophosphate synthase through RNA interference in mice. Biomed Res Int 2015 2
22 25918730 Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process. J Diabetes Res 2015 1
23 26447203 FDP-E induces adipocyte inflammation and suppresses insulin-stimulated glucose disposal: effect of inflammation and obesity on fibrinogen Bβ mRNA. Am J Physiol Cell Physiol 2015 Dec 1 1
24 28008986 Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodeling. Sci Rep 2016 Dec 23 2
25 28339090 Inhibition of farnesyl pyrophosphate synthase attenuates high glucose‑induced vascular smooth muscle cells proliferation. Mol Med Rep 2017 May 8
26 28843826 Zoledronic acid, an FPPS inhibitor, ameliorates liver steatosis through inhibiting hepatic de novo lipogenesis. Eur J Pharmacol 2017 Nov 5 3
27 29163482 Current Advances in γδ T Cell-Based Tumor Immunotherapy. Front Immunol 2017 4
28 29600563 Alendronate induces osteoclast precursor apoptosis via peroxisomal dysfunction mediated ER stress. J Cell Physiol 2018 Sep 2
29 29864496 Overexpression of farnesyl pyrophosphate synthase increases myocardial ischemia/reperfusion injury in mice. Gene 2018 Sep 25 2
30 30806252 Immunomodulatory Activities of Polysaccharides from White Button Mushroom, Agaricus bisporus (Agaricomycetes), Fruiting Bodies and Cultured Mycelia in Healthy and Immunosuppressed Mice. Int J Med Mushrooms 2019 4
31 30914801 FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis. Oncogene 2019 Jun 2
32 31040210 Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis. Proc Natl Acad Sci U S A 2019 May 14 1
33 31917888 Conjugated Linoleic Acid and Alpha Linolenic Acid Improve Cholesterol Homeostasis in Obesity by Modulating Distinct Hepatic Protein Pathways. Mol Nutr Food Res 2020 Apr 4
34 32389800 Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet. Brain Res Bull 2020 Aug 4
35 32529062 Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells. Heliyon 2020 Jun 1
36 33316294 Hyperglycemia induces RAGE-dependent hippocampal spatial memory impairments. Physiol Behav 2021 Feb 1 1
37 34467534 Cardiac-specific deletion of FDPS induces cardiac remodeling and dysfunction by enhancing the activity of small GTP-binding proteins. J Pathol 2021 Dec 1