cytochrome P450 family 2 subfamily C member 18 ; Homo sapiens






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1 1306110 Partial sequence and polymerase chain reaction-mediated analysis of expression of the human CYP2C18 gene. Pharmacogenetics 1992 Jun 1
2 1896026 Polymerase chain reaction-directed identification, cloning, and quantification of human CYP2C18 mRNA. Mol Pharmacol 1991 Sep 2
3 7656504 Clinical pharmacokinetics of lansoprazole. Clin Pharmacokinet 1995 Jun 2
4 8333835 Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18. Biochem Biophys Res Commun 1993 Jul 15 3
5 8894508 Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes. Drug Metab Dispos 1996 Oct 1
6 8944768 Oxidation of tienilic acid by human yeast-expressed cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this drug is a mechanism-based inhibitor specific for cytochrome P-450 2C9. Eur J Biochem 1996 Nov 1 4
7 9241661 Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation. Pharmacogenetics 1997 Jun 9
8 9733665 Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation. Drug Metab Dispos 1998 Sep 4
9 9766669 Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy. Cancer Res 1998 Oct 1 2
10 10387023 Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18. Biochemistry 1999 Jun 15 3
11 10449188 Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways. Biochem Pharmacol 1999 Sep 1 1
12 10901692 CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone. Drug Metab Dispos 2000 Aug 5
13 11558570 Metabolism and interaction of bisphenol A in human hepatic cytochrome P450 and steroidogenic CYP17. Biol Pharm Bull 2001 Sep 2
14 11714868 Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. J Pharmacol Exp Ther 2001 Dec 2
15 11853173 Inhibition of human hepatic cytochrome P450s and steroidogenic CYP17 by nonylphenol. Biol Pharm Bull 2002 Feb 1
16 12378636 Establishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a CYP2C18 clone with exon 5 missing. World J Gastroenterol 2002 Oct 2
17 12734935 [Stereoselective determination of propranolol enantiomer in transgenic cell lines expressing human cytochrome P450]. Zhejiang Da Xue Xue Bao Yi Xue Ban 2003 Apr 1
18 15301741 Enzyme activity analysis of CYP2C18 with exon 5 skipped. Acta Pharmacol Sin 2004 Aug 5
19 16141545 Contribution of human hepatic cytochrome p450 isoforms to the metabolism of psychotropic drugs. Biol Pharm Bull 2005 Sep 1
20 16978758 In vitro metabolism of tributyltin and triphenyltin by human cytochrome P-450 isoforms. Toxicology 2006 Dec 7 1
21 16985168 Differentiation-specific factors modulate epidermal CYP1-4 gene expression in human skin in response to retinoic acid and classic aryl hydrocarbon receptor ligands. J Pharmacol Exp Ther 2006 Dec 1
22 17084997 Ethanol oxidation into acetaldehyde by 16 recombinant human cytochrome P450 isoforms: role of CYP2C isoforms in human liver microsomes. Toxicol Lett 2006 Dec 15 2
23 18274956 Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements. Xenobiotica 2008 Mar 1
24 18276835 Generation of mice transgenic for human CYP2C18 and CYP2C19: characterization of the sexually dimorphic gene and enzyme expression. Drug Metab Dispos 2008 May 2
25 19038035 Few alterations in clinical pathology and histopathology observed in a CYP2C18&19 humanized mice model. Acta Vet Scand 2008 Nov 27 4
26 19339376 Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormone. Drug Metab Dispos 2009 Jul 1
27 19578179 A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet 2009 Oct 1 3
28 19706858 Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009 Aug 26 1
29 19958090 Genetic determinants of warfarin dosing in the Han-Chinese population. Pharmacogenomics 2009 Dec 1
30 23089684 Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates. Pharmacogenet Genomics 2012 Dec 1
31 23743505 Determination of oxycodone, noroxycodone and oxymorphone by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in human matrices: in vivo and in vitro applications. J Anal Toxicol 2013 Jul-Aug 2
32 25350082 In vitro profiling of the metabolism and drug-drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYP. Xenobiotica 2015 Mar 2
33 27896399 Cytochrome P450-mediated metabolism of triclosan attenuates its cytotoxicity in hepatic cells. Arch Toxicol 2017 Jun 2
34 28280103 Association of genetic variant and platelet function in patients undergoing neuroendovascular stenting. Postgrad Med J 2017 Sep 2
35 29458047 Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics. Biochem Pharmacol 2018 Jul 1
36 30899365 Induction of airway progenitor cells via p63 and KLF11 by Rho-kinase inhibitor Y27632 in hTERT-human nasal epithelial cells. Am J Transl Res 2019 1
37 31979355 Dapagliflozin Inhibits Cell Adhesion to Collagen I and IV and Increases Ectodomain Proteolytic Cleavage of DDR1 by Increasing ADAM10 Activity. Molecules 2020 Jan 23 1
38 32077582 Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients. J Thromb Haemost 2020 Jun 1
39 33759177 A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram. Clin Pharmacol Ther 2021 Sep 1
40 35282004 New associations of serum β-carotene, lycopene, and zeaxanthin concentrations with <i>NR1H3</i>, <i>APOB</i>, <i>RDH12</i>, AND <i>CYP</i> genes. Food Sci Nutr 2022 Mar 3