XPA, DNA damage recognition and repair factor ; Homo sapiens






235 Article(s)
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1 1380654 Xeroderma pigmentosum group A correcting protein from calf thymus. Mutat Res 1992 Sep 1
2 1764072 Molecular cloning of human XPAC gene homologs from chicken, Xenopus laevis and Drosophila melanogaster. Biochem Biophys Res Commun 1991 Dec 31 3
3 2239299 Flowcytometric analysis of DNA pattern of cells derived from xeroderma pigmentosum A--hypersensitivity to vincristine, etoposide and methotrexate. Acta Paediatr Jpn 1990 Jun 1
4 2366820 Correction of the ultraviolet light induced DNA-repair defect in xeroderma pigmentosum cells by electroporation of a normal human endonuclease. Mutat Res 1990 Jul 1
5 2507185 Clustered repair of excisable 4-nitroquinoline-1-oxide adducts in a larger fraction of genomic DNA of xeroderma pigmentosum complementation group C cells. Carcinogenesis 1989 Oct 2
6 3336371 Two DNA endonuclease activities from normal human and xeroderma pigmentosum chromatin active on psoralen plus ultraviolet light treated DNA. Mutat Res 1988 Jan 3
7 3921271 Defective repair of a class of 4NQO-induced alkali-labile DNA lesions in xeroderma pigmentosum complementation group A fibroblasts. Carcinogenesis 1985 Apr 1
8 3974621 Confluent holding leads to a transient enhancement in mutagenesis in UV-light-irradiated xeroderma pigmentosum, Gardner's syndrome and normal human diploid fibroblasts. Mutat Res 1985 Mar 1
9 6661418 Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2. Biochemistry 1983 Dec 6 3
10 7127674 Alkali-sensitive sites in DNA from human cells treated with ultraviolet light, 1'-acetoxysafrole or 1'-acetoxyestragole. Carcinogenesis 1982 2
11 7504187 Complementation of xeroderma pigmentosum cells by microinjection of mRNA fractionated under denaturing conditions: an estimation of sizes of XP-E and XP-G mRNA. Mutat Res 1994 Jan 4
12 7526200 The XPA protein is a zinc metalloprotein with an ability to recognize various kinds of DNA damage. Mutat Res 1994 Nov 1
13 7598728 Enhancement of damage-specific DNA binding of XPA by interaction with the ERCC1 DNA repair protein. Biochem Biophys Res Commun 1995 Jun 26 1
14 7662121 Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts. Mol Carcinog 1995 Feb 4
15 7891694 Mutations in XPA that prevent association with ERCC1 are defective in nucleotide excision repair. Mol Cell Biol 1995 Apr 2
16 8040325 Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 1994 Aug 2
17 8101209 Absence of DNA repair deficiency in the confirmed heterozygotes of xeroderma pigmentosum group A. J Invest Dermatol 1993 Jul 2
18 8218288 Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Biochemistry 1993 Nov 16 1
19 8253091 Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F. EMBO J 1993 Sep 1
20 8353849 Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector. Carcinogenesis 1993 Aug 1
21 8504485 Deficient gene specific repair of cisplatin-induced lesions in Xeroderma pigmentosum and Fanconi's anemia cell lines. Carcinogenesis 1993 May 2
22 8538652 Identification of a damaged-DNA binding domain of the XPA protein. Mutat Res 1996 Jan 2 4
23 8576098 Separation of protein factors that correct the defects in the seven complementation groups of xeroderma pigmentosum cells. J Biochem 1995 Oct 2
24 8660947 Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts. Exp Cell Res 1996 Jul 10 1
25 8671736 Chromatid exchanges may be induced by damage in sites of transcriptional activity. Mutagenesis 1996 Mar 3
26 8973600 Enhanced XPA mRNA levels in cisplatin-resistant human ovarian cancer are not associated with XPA mutations or gene amplification. Cancer Lett 1996 Nov 29 2
27 9034344 Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein. EMBO J 1997 Feb 3 1
28 9045683 A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A. J Biol Chem 1997 Mar 7 1
29 9054619 A processive versus a distributive mechanism of action correlates with differences in ability of normal and xeroderma pigmentosum group A endonucleases to incise damaged nucleosomal DNA. Carcinogenesis 1997 Feb 3
30 9078375 Implications of the zinc-finger motif found in the DNA-binding domain of the human XPA protein. Genes Cells 1996 May 1
31 9195337 Human nucleotide excision repair protein XPA: 1H NMR and CD solution studies of a synthetic peptide fragment corresponding to the zinc-binding domain (101-141). J Biomol Struct Dyn 1997 Jun 6
32 9592168 Structural features of the minimal DNA binding domain (M98-F219) of human nucleotide excision repair protein XPA. Nucleic Acids Res 1998 Jun 1 2
33 9618470 Assembly, subunit composition, and footprint of human DNA repair excision nuclease. Proc Natl Acad Sci U S A 1998 Jun 9 1
34 9698541 Interactions of the transcription/DNA repair factor TFIIH and XP repair proteins with DNA lesions in a cell-free repair assay. J Mol Biol 1998 Aug 14 1
35 9761477 Human nucleotide excision repair protein XPA: extended X-ray absorption fine-structure evidence for a metal-binding domain. Protein Sci 1998 Sep 7
36 10074455 Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours. Curr Biol 1999 Mar 11 4
37 10206960 Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide. J Biol Chem 1999 Apr 23 2
38 10357771 Inverse correlation between p53 protein levels and DNA repair efficiency in human fibroblast strains treated with 4-nitroquinoline 1-oxide: evidence that lesions other than DNA strand breaks trigger the p53 response. Carcinogenesis 1999 Jun 1
39 10405289 Electrospray ionization-mass spectrometry study of the interaction of cisplatin-adducted oligonucleotides with human XPA minimal binding domain protein. Anal Biochem 1999 Jul 15 7
40 10454616 Photocrosslinking locates a binding site for the large subunit of human replication protein A to the damaged strand of cisplatin-modified DNA. Nucleic Acids Res 1999 Aug 1 1
41 10493501 Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins. Cancer Res 1999 Sep 15 2
42 10498252 Partial functional correction of xeroderma pigmentosum group A cells by suppressor tRNA. Hum Gene Ther 1999 Sep 1 1
43 10563794 Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies. Biochemistry 1999 Nov 16 8
44 10626358 Interactions of mammalian proteins with cisplatin-damaged DNA. J Inorg Biochem 1999 Oct 1
45 10720735 Interference by toxic metal compounds with isolated zinc finger DNA repair proteins. Toxicol Lett 2000 Mar 15 1
46 10752124 [UV-induced immobilization of DNA repair protein XPA in different human cell line]. Tsitologiia 2000 1
47 10783332 Cadmium mutagenicity and human nucleotide excision repair protein XPA: CD, EXAFS and (1)H/(15)N-NMR spectroscopic studies on the zinc(II)- and cadmium(II)-associated minimal DNA-binding domain (M98-F219). Carcinogenesis 2000 May 3
48 10828957 RPA stabilizes the XPA-damaged DNA complex through protein-protein interaction. Biochemistry 2000 May 30 3
49 10833384 Overexpression and purification of human XPA using a baculovirus expression system. Protein Expr Purif 2000 Jun 3
50 10864225 Preclinical perspectives on platinum resistance. Drugs 2000 1