| 1 | 12727805 | Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643. | Carcinogenesis | 2003 Apr |
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| 2 | 14633691 | Inhibitor of nuclear factor kappaB kinase deficiency enhances oxidative stress and prolongs c-Jun NH2-terminal kinase activation induced by arsenic. | Cancer Res | 2003 Nov 15 |
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| 3 | 15797874 | NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation. | J Biol Chem | 2005 Jun 3 |
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| 4 | 16170381 | Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis. | Oncogene | 2005 Nov 3 |
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| 5 | 16732331 | Hematopoietic cells from gadd45a-deficient and gadd45b-deficient mice exhibit impaired stress responses to acute stimulation with cytokines, myeloablation and inflammation. | Oncogene | 2006 Sep 7 |
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| 6 | 17533171 | The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b. | Toxicol Sci | 2007 Sep |
3 |
| 7 | 17659913 | Gadd45 in the response of hematopoietic cells to genotoxic stress. | Blood Cells Mol Dis | 2007 Nov-Dec |
4 |
| 8 | 18424767 | CREB has a context-dependent role in activity-regulated transcription and maintains neuronal cholesterol homeostasis. | FASEB J | 2008 Aug |
2 |
| 9 | 18925944 | Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT. | BMC Genomics | 2008 Oct 16 |
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| 10 | 18977442 | Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries. | Neurobiol Dis | 2009 Jan |
1 |
| 11 | 19100860 | Dose-dependent alterations in gene expression in mouse liver induced by diethylnitrosamine and ethylnitrosourea and determined by quantitative real-time PCR. | Mutat Res | 2009 Feb 19 |
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| 12 | 20048163 | GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes. | J Biol Chem | 2010 Mar 12 |
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| 13 | 20404936 | Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. | PLoS One | 2010 Apr 12 |
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| 14 | 20558744 | Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor. | J Biol Chem | 2010 Aug 13 |
8 |
| 15 | 21352949 | Caffeine alters circadian rhythms and expression of disease and metabolic markers. | Int J Biochem Cell Biol | 2011 May |
2 |
| 16 | 21497500 | All-trans retinoic acid modifies the expression of clock and disease marker genes. | J Nutr Biochem | 2012 Mar |
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| 17 | 21505039 | Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. | Mol Pharmacol | 2011 Jul |
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| 18 | 22307729 | Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling. | J Cell Physiol | 2012 Nov |
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| 19 | 23681232 | GADD45β mediates p53 protein degradation via Src/PP2A/MDM2 pathway upon arsenite treatment. | Cell Death Dis | 2013 May 16 |
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| 20 | 23684557 | Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers. | Toxicol Appl Pharmacol | 2013 Sep 1 |
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| 21 | 23939942 | Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3. | Hepatology | 2014 Feb |
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| 22 | 25681557 | Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice. | J Hepatol | 2015 Jul |
9 |
| 23 | 25948499 | Aphidicolin inhibits cell proliferation via the p53-GADD45β pathway in AtT-20 cells. | Endocr J | 2015 |
4 |
| 24 | 26842245 | Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. | Alcohol Clin Exp Res | 2016 Feb |
3 |
| 25 | 26875664 | Gadd45β ameliorates L-DOPA-induced dyskinesia in a Parkinson's disease mouse model. | Neurobiol Dis | 2016 May |
7 |
| 26 | 27105496 | Gadd45b deficiency promotes premature senescence and skin aging. | Oncotarget | 2016 May 10 |
4 |
| 27 | 27137487 | Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health. | EMBO Mol Med | 2016 Jun |
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| 28 | 27233605 | PPARα activation drives demethylation of the CpG islands of the Gadd45b promoter in the mouse liver. | Biochem Biophys Res Commun | 2016 Aug 5 |
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| 29 | 27385273 | Cell death caused by the synergistic effects of zinc and dopamine is mediated by a stress sensor gene Gadd45b - implication in the pathogenesis of Parkinson's disease. | J Neurochem | 2016 Oct |
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| 30 | 27562556 | Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. | Toxicol Sci | 2016 Dec |
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| 31 | 28900541 | Simultaneous silencing of ACSL4 and induction of GADD45B in hepatocellular carcinoma cells amplifies the synergistic therapeutic effect of aspirin and sorafenib. | Cell Death Discov | 2017 |
2 |
| 32 | 29716964 | Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver. | Mol Cancer Res | 2018 Aug |
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| 33 | 29943110 | Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner. | Arch Toxicol | 2018 Aug |
2 |
| 34 | 30195037 | Growth arrest and DNA-damage-inducible 45 beta (GADD45β) deletion suppresses testosterone-induced prostate hyperplasia in mice. | Life Sci | 2018 Oct 15 |
4 |
| 35 | 30279966 | Loss of Gadd45b accelerates BCR-ABL-driven CML. | Oncotarget | 2018 Sep 7 |
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| 36 | 30564095 | Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors. | Front Mol Neurosci | 2018 |
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| 37 | 31311554 | Menstrual blood derived mesenchymal stem cells combined with Bushen Tiaochong recipe improved chemotherapy-induced premature ovarian failure in mice by inhibiting GADD45b expression in the cell cycle pathway. | Reprod Biol Endocrinol | 2019 Jul 16 |
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| 38 | 32114412 | Vestitol drives LPS-activated macrophages into M2 phenotype through modulation of NF-κB pathway. | Int Immunopharmacol | 2020 Feb 27 |
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| 39 | 32927466 | Regulation of dopamine-dependent transcription and cocaine action by Gadd45b. | Neuropsychopharmacology | 2021 Mar |
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| 40 | 33279798 | Status epilepticus induced Gadd45b is required for augmented dentate neurogenesis. | Stem Cell Res | 2020 Dec |
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| 41 | 33391480 | Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis. | Theranostics | 2021 |
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| 42 | 33643822 | <i>Gadd45b</i> is required in part for the anti-obesity effect of constitutive androstane receptor (CAR). | Acta Pharm Sin B | 2021 Feb |
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| 43 | 33676788 | Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis. | J Dermatol Sci | 2021 Apr |
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