kinesin family member 2A ; Homo sapiens

35 Article(s)
Pub. Date
#Total Relationship(s)
1 15302853 The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. J Cell Biol 2004 Aug 16 2
2 17538014 The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol Biol Cell 2007 Aug 1
3 18261724 Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. Exp Cell Res 2008 Apr 1 3
4 20471270 Neck linker length determines the degree of processivity in kinesin-1 and kinesin-2 motors. Curr Biol 2010 May 25 2
5 21544223 Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics Simulations. Cell Mol Bioeng 2009 Jun 1 1
6 22307638 Phosphatidylinositol 4-phosphate 5-kinase alpha (PIPKα) regulates neuronal microtubule depolymerase kinesin, KIF2A and suppresses elongation of axon branches. Proc Natl Acad Sci U S A 2012 Jan 31 2
7 23570661 Stable gene-silence of Kif2a synergistic with 5-fluorouracil suppresses oral tongue squamous cell carcinoma growth in vitro and in vivo. Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Jul 3
8 27531749 Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1). J Biol Chem 2016 Oct 7 1
9 27747449 Recurrent KIF2A mutations are responsible for classic lissencephaly. Neurogenetics 2017 Apr 1
10 27913662 Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1). J Biol Chem 2016 Dec 2 1
11 28903043 Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation. Cell Rep 2017 Sep 12 2
12 29077851 Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. Hum Mol Genet 2018 Jan 15 1
13 29313800 KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring. Elife 2018 Jan 9 2
14 29401437 Motor Reattachment Kinetics Play a Dominant Role in Multimotor-Driven Cargo Transport. Biophys J 2018 Jan 23 1
15 29781531 Down-regulation of KIF2A inhibits gastric cancer cell invasion via suppressing MT1-MMP. Clin Exp Pharmacol Physiol 2018 Oct 1
16 29844014 An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules. J Biol Chem 2018 Jul 20 3
17 29980677 Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate. Nat Commun 2018 Jul 6 3
18 30646587 Force Dependence of Velocity and Run Length of Kinesin-1, Kinesin-2 and Kinesin-5 Family Molecular Motors. Molecules 2019 Jan 14 1
19 30813343 Regulation of <i>KIF2A</i> by Antitumor <i>miR-451a</i> Inhibits Cancer Cell Aggressiveness Features in Lung Squamous Cell Carcinoma. Cancers (Basel) 2019 Feb 22 1
20 30980863 Bisphenol A disrupts mitotic progression via disturbing spindle attachment to kinetochore and centriole duplication in cancer cell lines. Toxicol In Vitro 2019 Sep 1
21 31514228 KIF2 mediates the neuroprotection in cerebral ischaemia injury by affecting NF-κB pathway. Clin Exp Pharmacol Physiol 2020 Feb 4
22 31858647 Kinesin family member 2A high expression correlates with advanced tumor stages and worse prognosis in non-small cell lung cancer patients. J Clin Lab Anal 2020 Apr 5
23 32833501 Knockdown of circHIPK3 Facilitates Temozolomide Sensitivity in Glioma by Regulating Cellular Behaviors Through miR-524-5p/KIF2A-Mediated PI3K/AKT Pathway. Cancer Biother Radiopharm 2021 Sep 7
24 32976381 Long Non-Coding RNA Paternally Expressed Imprinted Gene 10 (PEG10) Elevates Diffuse Large B-Cell Lymphoma Progression by Regulating Kinesin Family Member 2A (KIF2A) via Targeting MiR-101-3p. Med Sci Monit 2020 Sep 25 2
25 33082143 A kinetic dissection of the fast and superprocessive kinesin-3 KIF1A reveals a predominant one-head-bound state during its chemomechanical cycle. J Biol Chem 2020 Dec 25 2
26 33144324 KIF3A accelerates KIF3C within the kinesin-2 heterodimer to generate symmetrical phosphate release rates for each processive step. J Biol Chem 2021 Jan-Jun 1
27 33234597 Separable roles for RanGTP in nuclear and ciliary trafficking of a kinesin-2 subunit. J Biol Chem 2021 Jan-Jun 2
28 33495322 Mechanistic basis of propofol-induced disruption of kinesin processivity. Proc Natl Acad Sci U S A 2021 Feb 2 1
29 33513284 Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. FEBS Open Bio 2021 Mar 3
30 33713978 The clinical value of kinesin superfamily protein 2A in hepatocellular carcinoma. Clin Res Hepatol Gastroenterol 2021 Jul 1
31 34017375 Kinesin family member 2A promotes cancer cell viability, mobility, stemness, and chemoresistance to cisplatin by activating the PI3K/AKT/VEGF signaling pathway in non-small cell lung cancer. Am J Transl Res 2021 5
32 34024242 Circular RNA circ_0010235 sponges miR-338-3p to play oncogenic role in proliferation, migration and invasion of non-small-cell lung cancer cells through modulating KIF2A. Ann Med 2021 Dec 1
33 34792179 Kinesin family member 2A acts as a potential prognostic marker and treatment target via interaction with PI3K/AKT and RhoA/ROCK pathways in acute myeloid leukemia. Oncol Rep 2022 Jan 1
34 35173830 The molecular mechanism of kinesin family member 2A (KIF2A) underlying non-small cell lung cancer: the effect of its knockdown on malignant behaviors, stemness, chemosensitivity, and potential regulated signaling pathways. Am J Transl Res 2022 2
35 35313389 Kinesin family member 2A links with advanced tumor stage, reduced chemosensitivity and worse prognosis in gastric cancer. J Clin Lab Anal 2022 May 1