claudin 2 ; Mus musculus






43 Article(s)
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1 15308585 Oncogenic Raf-1 regulates epithelial to mesenchymal transition via distinct signal transduction pathways in an immortalized mouse hepatic cell line. Carcinogenesis 2004 Dec 2
2 15569684 Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells. J Biol Chem 2005 Feb 4 1
3 19423758 The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. Endocrinology 2009 Aug 2
4 20214989 Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D. J Steroid Biochem Mol Biol 2010 Jul 1
5 20385797 Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. Proc Natl Acad Sci U S A 2010 Apr 27 2
6 23303670 STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. J Immunol 2013 Feb 15 1
7 23306855 Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling. Dig Dis Sci 2013 Jun 3
8 23369528 Inhibition of extracellular signal-regulated kinase downregulates claudin-2 expression and alters paracellular permeability in mouse rectum CMT93-II cells. Tissue Cell 2013 Jun 2
9 23971882 Faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice DSS colitis. Scand J Gastroenterol 2013 Oct 1
10 24030525 Chloride channel ClC-2 is a key factor in the development of DSS-induced murine colitis. Inflamm Bowel Dis 2013 Dec 1
11 24264043 Alteration of tight junction gene expression by calcium- and vitamin D-deficient diet in the duodenum of calbindin-null mice. Int J Mol Sci 2013 Nov 20 2
12 25068494 Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice. Gastroenterology 2014 Nov 2
13 25838986 IL-9 regulates intestinal barrier function in experimental T cell-mediated colitis. Tissue Barriers 2015 1
14 26041780 1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components. J Biol Chem 2015 Jul 17 1
15 26212084 Tight junction CLDN2 gene is a direct target of the vitamin D receptor. Sci Rep 2015 Jul 27 3
16 27214555 Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest 2016 Jul 1 5
17 28452575 Paracellular transport as a strategy for energy conservation by multicellular organisms? Tissue Barriers 2017 Apr 3 1
18 28617689 Paracellular transport and energy utilization in the renal tubule. Curr Opin Nephrol Hypertens 2017 Sep 3
19 28618266 IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. Cell Host Microbe 2017 Jun 14 2
20 28939904 Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets. Sci Rep 2017 Sep 22 4
21 29474583 Ochratoxin A, citrinin and deoxynivalenol decrease claudin-2 expression in mouse rectum CMT93-II cells. Microscopy (Oxf) 2018 Apr 1 3
22 29751049 Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness. Toxicol Appl Pharmacol 2018 Jul 1 1
23 29939312 Intestinal barrier disruption and dysregulated mucosal immunity contribute to kidney fibrosis in chronic kidney disease. Nephrol Dial Transplant 2019 Mar 1 1
24 30406698 Zinc ameliorates intestinal barrier dysfunctions in shigellosis by reinstating claudin-2 and -4 on the membranes. Am J Physiol Gastrointest Liver Physiol 2019 Feb 1 2
25 30685787 Renal ischemia-reperfusion injury impairs renal calcium, magnesium, and phosphate handling in mice. Pflugers Arch 2019 Jun 1
26 31481470 Claudin-2 suppresses GEF-H1, RHOA, and MRTF, thereby impacting proliferation and profibrotic phenotype of tubular cells. J Biol Chem 2019 Oct 18 2
27 32092287 Differential day-night expression of tight junction components in murine retinal pigment epithelium. Exp Eye Res 2020 Apr 4
28 32149733 Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease. J Clin Invest 2020 Apr 1 6
29 32245617 Sennoside A restores colonic barrier function through protecting colon enterocytes from ROS-induced mitochondrial damage in diet-induced obese mice. Biochem Biophys Res Commun 2020 May 28 1
30 32322483 <i>Rumex japonicus</i> Houtt. alleviates dextran sulfate sodium-induced colitis by protecting tight junctions in mice. Integr Med Res 2020 Jun 1
31 32489707 Lactulose Suppresses Osteoclastogenesis and Ameliorates Estrogen Deficiency-Induced Bone Loss in Mice. Aging Dis 2020 May 1
32 32738096 Intestinal TLR9 deficiency exacerbates hepatic IR injury via altered intestinal inflammation and short-chain fatty acid synthesis. FASEB J 2020 Sep 1
33 32784362 TLR Antagonism by Sparstolonin B Alters Microbial Signature and Modulates Gastrointestinal and Neuronal Inflammation in Gulf War Illness Preclinical Model. Brain Sci 2020 Aug 8 1
34 33095778 In vivo and ex vivo assessment of bladder hyper-permeability and using molecular targeted magnetic resonance imaging to detect claudin-2 in a mouse model for interstitial cystitis. PLoS One 2020 3
35 33293626 Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers. Sci Rep 2020 Dec 8 2
36 33773208 Impaired airway epithelial barrier integrity was mediated by PI3Kδ in a mouse model of lipopolysaccharide-induced acute lung injury. Int Immunopharmacol 2021 Jun 2
37 33873095 Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice. Mol Immunol 2021 Jul 1
38 34414236 Brusatol-Enriched Brucea javanica Oil Ameliorated Dextran Sulfate Sodium-Induced Colitis in Mice: Involvement of NF-<i>κ</i>B and RhoA/ROCK Signaling Pathways. Biomed Res Int 2021 1
39 34426115 Terpinen4-ol inhibits heat stress induced inflammation in colonic tissue by Activating Occludin, Claudin-2 and TLR4/NF-κB signaling pathway. Int Immunopharmacol 2021 Oct 2
40 34663855 Effect of chitosan on blood profile, inflammatory cytokines by activating TLR4/NF-κB signaling pathway in intestine of heat stressed mice. Sci Rep 2021 Oct 18 1
41 34697992 Valsartan alleviates the blood-brain barrier dysfunction in db/db diabetic mice. Bioengineered 2021 Dec 3
42 34810264 Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis. Proc Natl Acad Sci U S A 2021 Nov 30 1
43 35166891 Genes modulating intestinal permeability and microbial community are dysregulated in sickle cell disease. Ann Hematol 2022 May 1