ectonucleotide pyrophosphatase/phosphodiesterase 1 ; Mus musculus






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1 1647027 Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1. Proc Natl Acad Sci U S A 1991 Jun 15 1
2 1715869 The plasma cell membrane glycoprotein, PC-1, is a threonine-specific protein kinase stimulated by acidic fibroblast growth factor. J Biol Chem 1991 Sep 5 1
3 7736322 Elevation of alkaline phosphatase activity induced by parathyroid hormone in osteoblast-like cells from the spinal hyperostotic mouse TWY (twy/twy). Calcif Tissue Int 1995 Feb 2
4 7813713 Emergence of mouse erythrocyte receptor, CD21, CD23, and PCA-1 in hairy cells during deoxycorformycin therapy. Eur J Haematol 1994 Nov 1
5 8001561 Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities. Eur J Biochem 1994 Dec 1 1
6 8223581 Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase). Eur J Biochem 1993 Oct 1 5
7 8917428 Threonine autophosphorylation and nucleotidylation of the hepatic membrane protein PC-1. Eur J Biochem 1996 Oct 15 2
8 11004006 Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1. Am J Physiol Regul Integr Comp Physiol 2000 Oct 1
9 11027689 Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases. J Biol Chem 2001 Jan 12 4
10 11856874 Isolation of novel mouse genes associated with ectopic ossification by differential display method using ttw, a mouse model for ectopic ossification. Cytogenet Cell Genet 2001 2
11 15039209 Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol 2004 Apr 1
12 15625282 Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice. Arterioscler Thromb Vasc Biol 2005 Apr 2
13 15677494 Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. Diabetes 2005 Feb 1
14 17911353 Renal calcium stones: insights from the control of bone mineralization. Exp Physiol 2008 Jan 1
15 18594151 Procyanidin C1 from apple extracts inhibits Fc epsilon RI-mediated mast cell activation. Int Arch Allergy Immunol 2008 2
16 18655772 Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification. Biochem Biophys Res Commun 2008 Sep 26 2
17 19401787 A comparative study of the effects of genistein, estradiol and raloxifene on the murine skeletal system. Acta Biochim Pol 2009 1
18 19577557 Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo. Eur J Pharmacol 2009 Aug 15 5
19 19733704 Inorganic pyrophosphatase induces type I collagen in osteoblasts. Bone 2010 Jan 1
20 20016754 Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy. Circ Cardiovasc Genet 2008 Dec 1
21 20048161 Proteoliposomes harboring alkaline phosphatase and nucleotide pyrophosphatase as matrix vesicle biomimetics. J Biol Chem 2010 Mar 5 13
22 20154452 The mechanism of mineralization and the role of alkaline phosphatase in health and disease. J Nippon Med Sch 2010 Feb 2
23 21099228 Arterial calcification is driven by RAGE in Enpp1-/- mice. J Vasc Res 2011 1
24 21289427 [Animal models for bone and joint disease. ttw (tiptoe walking), a model mouse of OPLL (ossification of the posterior longitudinal ligament of the spine)]. Clin Calcium 2011 Feb 2
25 21477221 Npp1 promotes atherosclerosis in ApoE knockout mice. J Cell Mol Med 2011 Nov 3
26 21678127 FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation. J Bone Miner Metab 2012 Jan 1
27 21930712 Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) protein regulates osteoblast differentiation. J Biol Chem 2011 Nov 11 1
28 22359666 Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice. PLoS One 2012 10
29 22510396 Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Ann Rheum Dis 2012 Jul 1
30 22750863 Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Jul 1 1
31 22842219 New insights into NPP1 function: lessons from clinical and animal studies. Bone 2012 Nov 2
32 23027977 Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc Natl Acad Sci U S A 2012 Oct 16 1
33 23798568 Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy. Dis Model Mech 2013 Sep 4
34 23962057 Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist. Br J Pharmacol 2013 Nov 2
35 24366459 Effects of extracellular phosphate on gene expression in murine osteoblasts. Calcif Tissue Int 2014 May 1
36 24717293 Vascular calcification is dependent on plasma levels of pyrophosphate. Kidney Int 2014 Jun 2
37 24947519 Ectonucleotide pyrophosphatase/phosphodiesterase activity in Neuro-2a neuroblastoma cells: changes in expression associated with neuronal differentiation. J Neurochem 2014 Nov 1
38 25260930 Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(-/-) mice. Bone 2014 Dec 6
39 25368121 Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes. Dis Model Mech 2014 Dec 2
40 25504209 Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis. Int J Oral Sci 2015 Mar 23 2
41 26033523 Acidosis is a key regulator of osteoblast ecto-nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity. J Cell Physiol 2015 Dec 1
42 26054750 1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5. Mol Cell Endocrinol 2015 Sep 5 4
43 26219706 Genetically Modified Mice for Studying TNAP Function. Subcell Biochem 2015 2
44 26509067 The H2 blocker famotidine suppresses progression of ossification of the posterior longitudinal ligament in a mouse model. RMD Open 2015 2
45 26763447 Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy. J Invest Dermatol 2016 Jan 2
46 27537838 E4orf1 Enhances Glucose Uptake Independent of Proximal Insulin Signaling. PLoS One 2016 1
47 27863377 Variable patterns of ectopic mineralization in Enpp1asj-2J mice, a model for generalized arterial calcification of infancy. Oncotarget 2016 Dec 20 3
48 28402956 Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy. Oncotarget 2017 Jun 13 1
49 28701330 Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO Mol Med 2017 Nov 3
50 28798354 Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions. Sci Rep 2017 Aug 10 8