ceramide synthase 6 ; Mus musculus






22 Article(s)
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1 22544924 Ceramide synthase 6 plays a critical role in the development of experimental autoimmune encephalomyelitis. J Immunol 2012 Jun 1 1
2 23760501 Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities. J Biol Chem 2013 Jul 19 3
3 23832510 Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides. Hepatology 2014 Jan 1
4 25173988 Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent. Biochem Pharmacol 2014 Nov 15 1
5 25295788 Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab 2014 Oct 7 6
6 25833068 Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils. Immunol Cell Biol 2015 Oct 1
7 26650179 Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. J Clin Invest 2016 Jan 3
8 28812434 [pemetrexed + sildenafil], via autophagy-dependent HDAC downregulation, enhances the immunotherapy response of NSCLC cells. Cancer Biol Ther 2017 Sep 2 3
9 29127192 Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes. FASEB J 2018 Mar 1
10 29374263 Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis. Sci Rep 2018 Jan 26 4
11 29416631 <i>In vitro</i> and <i>in vivo</i> anti-leukemic effects of cladoloside C<sub>2</sub> are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH<sub>2</sub>-terminal kinase/caspase-8. Oncotarget 2018 Jan 2 1
12 29472233 Novel Role of IL (Interleukin)-1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic Aneurysms. Arterioscler Thromb Vasc Biol 2018 Apr 1
13 29739864 Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR. J Lipid Res 2018 Jul 1
14 30054909 CerS6 regulates cisplatin resistance in oral squamous cell carcinoma by altering mitochondrial fission and autophagy. J Cell Physiol 2018 Dec 13
15 30655217 The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach. Mol Metab 2019 Mar 10
16 30706713 Modulation of Lipid Metabolism by Celastrol. J Proteome Res 2019 Mar 1 1
17 31676768 Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases. Exp Mol Med 2019 Nov 1 1
18 32902157 CERS6 required for cell migration and metastasis in lung cancer. J Cell Mol Med 2020 Oct 2
19 33844153 Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice. Neurotherapeutics 2021 Jul 1
20 33951438 Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response. Cell Rep 2021 May 4 1
21 34358645 Ceramide synthase 6 mediates sex-specific metabolic response to dietary folic acid in mice. J Nutr Biochem 2021 Dec 9
22 34805245 Dietary Folic Acid Alters Metabolism of Multiple Vitamins in a CerS6- and Sex-Dependent Manner. Front Nutr 2021 1