phospholipase A2 group VI ; Homo sapiens






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1 8113982 Effects of scalaradial, a type II phospholipase A2 inhibitor, on human neutrophil arachidonic acid mobilization and lipid mediator formation. J Pharmacol Exp Ther 1994 Feb 1
2 9079687 A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J Biol Chem 1997 Mar 28 6
3 9417066 Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity. J Biol Chem 1998 Jan 2 2
4 9593733 Fas-induced arachidonic acid release is mediated by Ca2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation. J Biol Chem 1998 May 29 3
5 9603953 The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2. J Biol Chem 1998 Jun 5 1
6 9751485 Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration. Endocrinology 1998 Oct 7
7 9887232 Phorbol 12-myristate 13-acetate stimulates lysophosphatidic acid secretion from ovarian and cervical cancer cells but not from breast or leukemia cells. Gynecol Oncol 1998 Dec 6
8 9915849 Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. J Biol Chem 1999 Jan 29 6
9 10092647 Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1. J Biol Chem 1999 Apr 2 10
10 10235450 Phospholipase A2 enzymes regulate alpha IIb beta3-mediated, but not Fc gammaRII receptor-mediated, pp125FAK phosphorylation in platelets. Thromb Haemost 1999 Apr 3
11 10336645 The human calcium-independent phospholipase A2 gene multiple enzymes with distinct properties from a single gene. Eur J Biochem 1999 Jun 2
12 10480488 Calcium dependency of arachidonic acid incorporation into cellular phospholipids of different cell types. Prostaglandins Other Lipid Mediat 1999 Jul 5
13 10558911 Ca(2+)-independent phospholipase A2 is required for alpha2-adrenergic-induced preadipocyte spreading. Biochem Biophys Res Commun 1999 Nov 19 3
14 10601704 Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells. Biochim Biophys Acta 2000 Jan 3 3
15 10747887 Distinct roles of two intracellular phospholipase A2s in fatty acid release in the cell death pathway. Proteolytic fragment of type IVA cytosolic phospholipase A2alpha inhibits stimulus-induced arachidonate release, whereas that of type VI Ca2+-independent phospholipase A2 augments spontaneous fatty acid release. J Biol Chem 2000 Jun 16 3
16 10799869 Potassium regulates IL-1 beta processing via calcium-independent phospholipase A2. J Immunol 2000 May 15 4
17 10893319 Induction of Ca-independent PLA(2) and conservation of plasmalogen polyunsaturated fatty acids in diabetic heart. Am J Physiol Endocrinol Metab 2000 Jul 2
18 10964913 Human calcium-independent phospholipase A2 mediates lymphocyte proliferation. J Biol Chem 2000 Nov 17 5
19 11118454 Identification of the calmodulin-binding domain of recombinant calcium-independent phospholipase A2beta. implications for structure and function. J Biol Chem 2001 Mar 9 1
20 11208136 Phospholipase A2 antagonists inhibit constitutive retrograde membrane traffic to the endoplasmic reticulum. Traffic 2000 Jun 5
21 11250126 Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease. Exp Gerontol 2001 Mar 2
22 11274966 The effect of high molecular phospholipase A2 inhibitors on 3T6 fibroblast proliferation. Biochem Pharmacol 2001 Apr 1 4
23 11371929 Stimulation of protease activated receptors on RT4 cells mediates arachidonic acid release via Ca2+ independent phospholipase A2. J Urol 2001 Jun 1
24 11525380 The molecular biology of the group VIA Ca2+-independent phospholipase A2. Prog Nucleic Acid Res Mol Biol 2001 6
25 11544333 Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. J Immunol 2001 Sep 15 3
26 11732912 Endothelial cell PAF synthesis following thrombin stimulation utilizes Ca(2+)-independent phospholipase A(2). Biochemistry 2001 Dec 11 10
27 11841807 Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors. Biochem Pharmacol 2002 Jan 15 1
28 11872155 Phospholipase A2. J Biochem 2002 Mar 1
29 12049633 Roles of various phospholipases A2 in providing lysophospholipid acceptors for fatty acid phospholipid incorporation and remodelling. Biochem J 2002 Jun 15 5
30 12089145 Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s. J Biol Chem 2002 Sep 6 1
31 12151641 Differential effects of polybrominated diphenyl ethers and polychlorinated biphenyls on [3H]arachidonic acid release in rat cerebellar granule neurons. Toxicol Sci 2002 Aug 3
32 12181317 Involvement of calcium-independent phospholipase A2 in hydrogen peroxide-induced accumulation of free fatty acids in human U937 cells. J Biol Chem 2002 Oct 25 7
33 12205049 Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism. FASEB J 2002 Sep 1
34 12384982 Calcium-independent phospholipase A2 through arachidonic acid mobilization is involved in Caco-2 cell growth. J Cell Physiol 2002 Dec 2
35 12432908 Phospholipase A2 enzymes. Prostaglandins Other Lipid Mediat 2002 Aug 1
36 12547829 Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry. J Biol Chem 2003 Apr 4 6
37 14560038 Inhibition of platelet-activating factor (PAF) acetylhydrolase by methyl arachidonyl fluorophosphonate potentiates PAF synthesis in thrombin-stimulated human coronary artery endothelial cells. J Pharmacol Exp Ther 2003 Dec 4
38 14730314 A novel mechanism for the store-operated calcium influx pathway. Nat Cell Biol 2004 Feb 6
39 14749285 Islet complex lipids: involvement in the actions of group VIA calcium-independent phospholipase A(2) in beta-cells. Diabetes 2004 Feb 7
40 15003994 A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation. FASEB J 2004 Mar 2
41 15007079 Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells. J Biol Chem 2004 May 21 5
42 15252038 Role of group VIA calcium-independent phospholipase A2 in arachidonic acid release, phospholipid fatty acid incorporation, and apoptosis in U937 cells responding to hydrogen peroxide. J Biol Chem 2004 Sep 24 1
43 15305016 Cellular function of calcium-independent phospholipase A2. Biol Pharm Bull 2004 Aug 1
44 15320787 Catalytic features, regulation and function of myocardial phospholipase A2. Curr Med Chem Cardiovasc Hematol Agents 2004 Jul 6
45 15358201 The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochem Biophys Res Commun 2004 Aug 20 2
46 15385540 Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity. J Biol Chem 2004 Dec 17 4
47 15573142 The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cells. Can J Physiol Pharmacol 2004 Oct 6
48 15630695 AMPA receptor phosphorylation is selectively regulated by constitutive phospholipase A(2) and 5-lipoxygenase activities. Hippocampus 2005 7
49 15643055 Calcium-independent phospholipase A2 is regulated by a novel protein kinase C in human coronary artery endothelial cells. Am J Physiol Cell Physiol 2005 Feb 6
50 15685208 Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2. Br J Pharmacol 2005 Apr 7