myosin regulatory light chain interacting protein ; Homo sapiens






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1 1548940 Selected pharmacologic characteristics of idarubicin and idarubicinol. Leukemia 1992 1
2 8690513 Cellular pharmacology of idarubicinol in multidrug-resistant LoVo cell lines. Int J Cancer 1996 Jul 3 1
3 14565163 Phase 2 study of idarubicin in pediatric brain tumors: Pediatric Oncology Group study POG 9237. Neuro Oncol 2003 Oct 4
4 19783832 Cholesterol worships a new idol. J Mol Cell Biol 2009 Dec 3
5 20410187 Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells. Haematologica 2010 Aug 1
6 21069265 Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression. Int J Mol Med 2011 Jan 2
7 21685362 The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor. Genes Dev 2011 Jun 15 1
8 21734303 Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL). J Biol Chem 2011 Aug 26 1
9 21765216 The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans. J Clin Invest 2011 Aug 1
10 21859674 Transcriptional and posttranscriptional control of cholesterol homeostasis by liver X receptors. Cold Spring Harb Symp Quant Biol 2011 1
11 22059152 An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. Cancer Discov 2011 Oct 1
12 22109552 FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors. Proc Natl Acad Sci U S A 2011 Dec 13 3
13 22331829 Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial. Circ Cardiovasc Genet 2012 Apr 1 1
14 22347519 Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment. Am J Transl Res 2012 2
15 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. Carcinogenesis 2012 Jul 2
16 22752225 Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters. Mol Cancer Ther 2012 Sep 1
17 22936343 Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. Arterioscler Thromb Vasc Biol 2012 Nov 5
18 23107276 Association of MYLIP rs3757354 SNP and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids Health Dis 2012 Oct 29 1
19 23435093 From evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transport. Pharmacol Res 2013 Sep 4
20 23598417 MiR-590-5P inhibits growth of HepG2 cells via decrease of S100A10 expression and Inhibition of the Wnt pathway. Int J Mol Sci 2013 Apr 18 1
21 23678170 Epstein-Barr virus-encoded microRNA BART15-3p promotes cell apoptosis partially by targeting BRUCE. J Virol 2013 Jul 1
22 24045110 Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing. J Gen Virol 2013 Dec 4
23 24252850 The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells. Mol Cancer Ther 2014 Jan 1
24 24299514 miR-199a-5p silencing regulates the unfolded protein response in chronic obstructive pulmonary disease and α1-antitrypsin deficiency. Am J Respir Crit Care Med 2014 Feb 1 1
25 24334028 β-arrestin1-biased β1-adrenergic receptor signaling regulates microRNA processing. Circ Res 2014 Feb 28 2
26 24447928 Extracellular disposal of tumor-suppressor miRs-145 and -34a via microvesicles and 5-FU resistance of human colon cancer cells. Int J Mol Sci 2014 Jan 20 2
27 24872388 Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. Cancer Res 2014 Aug 15 1
28 25007957 MiR-9 regulates the post-transcriptional level of VEGF165a by targeting SRPK-1 in ARPE-19 cells. Graefes Arch Clin Exp Ophthalmol 2014 Sep 1
29 25023731 AAV vectors expressing LDLR gain-of-function variants demonstrate increased efficacy in mouse models of familial hypercholesterolemia. Circ Res 2014 Aug 29 1
30 25329888 Effects of miR-33a-5P on ABCA1/G1-mediated cholesterol efflux under inflammatory stress in THP-1 macrophages. PLoS One 2014 5
31 25394495 Docosahexanoic acid modifies low-density lipoprotein receptor abundance in HepG2 cells via suppression of the LXRα-Idol pathway. Mol Med Rep 2015 Mar 3
32 25427715 Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members. BMC Cancer 2014 Nov 25 2
33 25625875 Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes. Int J Oncol 2015 Apr 3
34 25927920 IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population. PLoS One 2015 1
35 25928907 MicroRNA expression profiles in liver and colon of sexually immature gilts after exposure to Fusarium mycotoxins. Pol J Vet Sci 2015 2
36 25990668 Association study of the miRNA-binding site polymorphisms of CDKN2A/B genes with gestational diabetes mellitus susceptibility. Acta Diabetol 2015 Oct 2
37 26153245 Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. Diabetes 2015 Oct 1
38 26527619 A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes. Mol Cell Biol 2016 Jan 15 1
39 26666640 The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL. Circ Res 2016 Feb 5 1
40 26719329 Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem 2016 Feb 26 2
41 26786161 Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol. Cardiovasc Res 2016 May 1 1
42 26846634 Foiling IDOL to Help Control Cholesterol. Circ Res 2016 Feb 5 1
43 27071970 RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol. Circ Cardiovasc Genet 2016 Jun 6
44 27284341 MicroRNA-138 suppresses proliferation, invasion and glycolysis in malignant melanoma cells by targeting HIF-1α. Exp Ther Med 2016 Jun 1
45 27353169 MiR-548an, Transcriptionally Downregulated by HIF1α/HDAC1, Suppresses Tumorigenesis of Pancreatic Cancer by Targeting Vimentin Expression. Mol Cancer Ther 2016 Sep 1
46 27465833 Evaluation of in vivo antitumor effects of low-frequency ultrasound-mediated miRNA-133a microbubble delivery in breast cancer. Cancer Med 2016 Sep 5
47 27649261 MiR-pharmacogenetics of methotrexate in childhood B-cell acute lymphoblastic leukemia. Pharmacogenet Genomics 2016 Nov 1
48 27667021 Proliferation of metanephric mesenchymal cells is inhibited by miR-743a-mediated WT1 suppression in vitro. Mol Med Rep 2016 Nov 2
49 27769200 Selumetinib suppresses cell proliferation, migration and trigger apoptosis, G1 arrest in triple-negative breast cancer cells. BMC Cancer 2016 Oct 21 1
50 27997916 Circulating miR-181a as a Potential Novel Biomarker for Diagnosis of Acute Myocardial Infarction. Cell Physiol Biochem 2016 1