1 | 1459457 | The proto-oncogene bcl-3 encodes an I kappa B protein. | Genes Dev | 1992 Dec |
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2 | 7479976 | Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination. | Proc Natl Acad Sci U S A | 1995 Nov 21 |
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3 | 7488149 | Cupric ion blocks NF kappa B activation through inhibiting the signal-induced phosphorylation of I kappa B alpha. | Biochem Biophys Res Commun | 1995 Nov 13 |
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4 | 7492771 | Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells. | Blood | 1995 Dec 1 |
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5 | 7499266 | Identification of an I kappa B alpha-associated protein kinase in a human monocytic cell line and determination of its phosphorylation sites on I kappa B alpha. | J Biol Chem | 1995 Nov 17 |
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6 | 7532282 | Transcription-independent turnover of I kappa B alpha during monocyte adherence: implications for a translational component regulating I kappa B alpha/MAD-3 mRNA levels. | Mol Cell Biol | 1995 Mar |
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7 | 7545393 | Inhibition of NF-kappa B by pyrrolidine dithiocarbamate blocks endothelial cell activation. | Biochem Biophys Res Commun | 1995 Sep 5 |
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8 | 7559628 | Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. | J Biol Chem | 1995 Oct 20 |
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9 | 7565683 | N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity. | Mol Cell Biol | 1995 Oct |
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10 | 7568127 | Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. | Proc Natl Acad Sci U S A | 1995 Sep 26 |
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11 | 7569975 | Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. | Science | 1995 Oct 13 |
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12 | 7575604 | Inactivation of NF-kappa B inhibitor I kappa B alpha: ubiquitin-dependent proteolysis and its degradation product. | Biochem Biophys Res Commun | 1995 Oct 4 |
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13 | 7594468 | Regulation of IkB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways. | J Immunol | 1995 Nov 15 |
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14 | 7628694 | Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway. | Genes Dev | 1995 Jul 1 |
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15 | 7629157 | Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. | J Biol Chem | 1995 Aug 4 |
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16 | 7642544 | Involvement of a putative protein-tyrosine phosphatase and I kappa B-alpha serine phosphorylation in nuclear factor kappa B activation by tumor necrosis factor. | J Biol Chem | 1995 Aug 11 |
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17 | 7675442 | I kappa B-alpha-mediated inhibition of nuclear transport and DNA-binding by Rel proteins are separable functions: phosphorylation of C-terminal serine residues of I kappa B-alpha is specifically required for inhibition of DNA-binding. | Oncogene | 1995 Sep 7 |
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18 | 7739562 | Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. | Mol Cell Biol | 1995 May |
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19 | 7744820 | Evidence in support of a role for human T-cell leukemia virus type I Tax in activating NF-kappa B via stimulation of signaling pathways. | J Biol Chem | 1995 May 19 |
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20 | 7775482 | Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. | J Biol Chem | 1995 Jun 9 |
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21 | 7796813 | Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. | EMBO J | 1995 Jun 15 |
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22 | 7814425 | Proteolytic processing of NF-kappa B/I kappa B in human monocytes. ATP-dependent induction by pro-inflammatory mediators. | J Biol Chem | 1995 Jan 6 |
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23 | 7878466 | Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. | Science | 1995 Mar 10 |
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24 | 7923153 | Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). | Cancer Res | 1994 Oct 15 |
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25 | 7929355 | Protease inhibitors block lipopolysaccharide induction of tissue factor gene expression in human monocytic cells by preventing activation of c-Rel/p65 heterodimers. | J Biol Chem | 1994 Oct 21 |
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26 | 7957109 | A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B. | EMBO J | 1994 Nov 15 |
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27 | 7966593 | Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3. | J Virol | 1994 Dec |
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28 | 7969133 | Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells. | Mol Cell Biol | 1994 Dec |
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29 | 7982907 | CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin. | J Biol Chem | 1994 Dec 2 |
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30 | 8096091 | NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. | Science | 1993 Mar 26 |
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31 | 8137243 | Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. | Cancer Res | 1994 Mar 15 |
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32 | 8188652 | Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system. | J Biol Chem | 1994 May 13 |
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33 | 8255759 | Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B. | Nucleic Acids Res | 1993 Nov 11 |
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34 | 8262046 | Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family. | EMBO J | 1993 Dec 15 |
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35 | 8413215 | NF-kappa B subunit-specific regulation of the interleukin-8 promoter. | Mol Cell Biol | 1993 Oct |
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36 | 8460169 | Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. | Proc Natl Acad Sci U S A | 1993 Mar 15 |
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37 | 8523586 | Hepatitis B virus pX activates NF-kappa B-dependent transcription through a Raf-independent pathway. | J Virol | 1996 Jan |
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38 | 8537390 | Regulation of NF-kappa B through the nuclear processing of p105 (NF-kappa B1) in Epstein-Barr virus-immortalized B cell lines. | J Biol Chem | 1995 Dec 29 |
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39 | 8601309 | Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. | Cell | 1996 Mar 22 |
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40 | 8622636 | Inhibitory effect of E3330, a novel quinone derivative able to suppress tumor necrosis factor-alpha generation, on activation of nuclear factor-kappa B. | Mol Pharmacol | 1996 May |
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41 | 8622692 | Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation. | Mol Cell Biol | 1996 Mar |
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42 | 8642242 | Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B. | J Exp Med | 1996 Mar 1 |
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43 | 8655581 | Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression. | J Cell Biol | 1996 Jun |
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44 | 8655651 | Appearance of apparently ubiquitin-conjugated I kappa B-alpha during its phosphorylation-induced degradation in intact cells. | J Cell Sci Suppl | 1995 |
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45 | 8657102 | Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation. | Mol Cell Biol | 1996 Apr |
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46 | 8660357 | Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors. | Biochem Biophys Res Commun | 1996 Jun 5 |
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47 | 8662925 | Characterization of IkappaB kinases. IkappaB-alpha is not phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II substrate. | J Biol Chem | 1996 Jun 7 |
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48 | 8668171 | Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha. | Mol Cell Biol | 1996 Jul |
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49 | 8709193 | Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication. | J Virol | 1996 Sep |
2 |
50 | 8797825 | Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. | Cell | 1996 Sep 6 |
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