fibronectin type III domain containing 5 ; Homo sapiens






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1 23018146 FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 2012 Dec 3
2 23219488 Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity--correlation with body mass index. Peptides 2013 Jan 1
3 23369227 Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract 2013 Apr 3
4 23637927 Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity. PLoS One 2013 1
5 23650203 Free fatty acid effects on myokine production in combination with exercise mimetics. Mol Nutr Food Res 2013 Aug 1
6 23665283 Irisin is inversely associated with intrahepatic triglyceride contents in obese adults. J Hepatol 2013 Sep 5
7 23667695 Decrease in irisin in patients with chronic kidney disease. PLoS One 2013 3
8 23866690 Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes. Lipids Health Dis 2013 Jul 18 2
9 24023786 Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo. PLoS One 2013 6
10 24140091 Irisin in patients with nonalcoholic fatty liver disease. Metabolism 2014 Feb 2
11 24188288 Irisin as a predictor of glucose metabolism in children: sexually dimorphic effects. Eur J Clin Invest 2014 Feb 4
12 24297848 Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. J Physiol 2014 Mar 1 7
13 24325584 Plasma irisin depletion under energy restriction is associated with improvements in lipid profile in metabolic syndrome patients. Clin Endocrinol (Oxf) 2014 Aug 2
14 24355429 Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery. Cytokine 2014 Feb 1
15 24397868 Maternal inheritance of circulating irisin in humans. Clin Sci (Lond) 2014 Jun 2
16 24398403 The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes. Am J Physiol Endocrinol Metab 2014 Mar 1 1
17 24399249 Serum levels of the myokine irisin in relation to metabolic and renal function. Eur J Endocrinol 2014 Apr 1
18 24567125 Higher baseline irisin concentrations are associated with greater reductions in glycemia and insulinemia after weight loss in obese subjects. Nutr Diabetes 2014 Feb 24 3
19 24599275 Circulating irisin is associated with osteoporotic fractures in postmenopausal women with low bone mass but is not affected by either teriparatide or denosumab treatment for 3 months. Osteoporos Int 2014 May 2
20 24721335 Three new players in energy regulation: preptin, adropin and irisin. Peptides 2014 Jun 1
21 24728416 Circulating irisin levels are not affected by coffee intake: a randomized controlled trial. PLoS One 2014 1
22 24850254 Serum irisin concentration in women with gestational diabetes. Gynecol Endocrinol 2014 Sep 4
23 24997768 Evaluation of circulating irisin levels in healthy young individuals after a single 100,000 IU vitamin D dose. Ann Endocrinol (Paris) 2014 Jul 3
24 25029417 Circulating irisin and glucose-dependent insulinotropic peptide are associated with the development of polycystic ovary syndrome. J Clin Endocrinol Metab 2014 Dec 1
25 25060690 Circulating irisin, omentin-1, and lipoprotein subparticles in adults at higher cardiovascular risk. Metabolism 2014 Oct 1
26 25102448 Serum irisin levels and thyroid function--newly discovered association. Peptides 2014 Oct 1
27 25119310 Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation. J Clin Endocrinol Metab 2014 Nov 1
28 25124080 Effects of the exercise-inducible myokine irisin on malignant and non-malignant breast epithelial cell behavior in vitro. Int J Cancer 2015 Feb 15 6
29 25192692 Association between irisin and homocysteine in euglycemic and diabetic subjects. Clin Biochem 2014 Dec 5
30 25276128 Circulating sclerostin and irisin are related and interact with gender to influence adiposity in adults with prediabetes. Int J Endocrinol 2014 1
31 25326905 Irisin has no effect on lipolysis in 3T3-L1 adipocytes or fatty acid metabolism in HepG2 hepatocytes. Endocrine 2015 May 5
32 25338001 Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis. PLoS One 2014 4
33 25352765 Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in men. Korean J Physiol Pharmacol 2014 Oct 3
34 25381603 Association between circulating irisin and homocysteine in patients with nonalcoholic fatty liver disease. Endocrine 2015 Jun 1
35 25497839 Enhanced expression of FNDC5 in human embryonic stem cell-derived neural cells along with relevant embryonic neural tissues. Gene 2015 Feb 25 1
36 25599805 Corrigendum to: Ursolic Acid-Induced Elevation of Serum Irisin Augments Muscle Strength During Resistance Training in Men. Korean J Physiol Pharmacol 2014 Dec 1
37 25675380 Elevated circulating levels of irisin and the effect of metformin treatment in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2015 Apr 5
38 25762196 Increased levels of irisin in people with long-standing Type 1 diabetes. Diabet Med 2015 Sep 1
39 25765248 Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans. Appetite 2015 Jul 1
40 25781361 Irisin and its relation to insulin resistance and puberty in obese children: a longitudinal analysis. J Clin Endocrinol Metab 2015 May 4
41 25814621 Association of irisin concentrations with the presence of diabetic nephropathy and retinopathy. Ann Clin Biochem 2016 Jan 5
42 25820474 Circulating irisin and glucose metabolism in overweight/obese women: effects of α-lipoic acid and eicosapentaenoic acid. J Physiol Biochem 2015 Sep 7
43 25820670 Central and peripheral irisin differentially regulate blood pressure. Cardiovasc Drugs Ther 2015 Apr 1
44 25826445 Irisin, a Novel Myokine, Regulates Glucose Uptake in Skeletal Muscle Cells via AMPK. Mol Endocrinol 2015 Jun 11
45 25859278 Associations of betatrophin levels with irisin in Chinese women with normal glucose tolerance. Diabetol Metab Syndr 2015 1
46 25869623 ERK1/2 is a key regulator of Fndc5 and PGC1α expression during neural differentiation of mESCs. Neuroscience 2015 Jun 25 4
47 25897751 Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects. PLoS One 2015 2
48 26054747 Dihydromyricetin stimulates irisin secretion partially via the PGC-1α pathway. Mol Cell Endocrinol 2015 Sep 5 4
49 26081427 Resistance exercise induces a greater irisin response than endurance exercise. Metabolism 2015 Sep 4
50 26111934 Circulating irisin levels are associated with lipid and uric acid metabolism in a Chinese population. Clin Exp Pharmacol Physiol 2015 Sep 12