nicotinamide nucleotide adenylyltransferase 1 ; Homo sapiens






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1 1524439 NAD biosynthesis in human placenta: purification and characterization of homogeneous NMN adenylyltransferase. Arch Biochem Biophys 1992 Oct 1
2 1781391 Pyridine nucleotide metabolism: purification and properties of NMN adenylyltransferase from human placenta. Adv Exp Med Biol 1991 1
3 2560924 [Metabolism of NAD+ in the nuclei of human placenta]. Boll Soc Ital Biol Sper 1989 Nov 2
4 6295757 NMN adenylyltransferase: its association with chromatin and with poly(ADP-ribose) polymerase. Eur J Biochem 1982 Nov 15 1
5 7872964 The antitumor drug, 1,3-bis(2-chloroethyl)-1-nitroso-urea, inactivates human nicotinamide mononucleotide adenylyltransferase. Biochem Pharmacol 1995 Feb 14 7
6 8470897 Nicotinamide mononucleotide adenylyltransferase activity in human erythrocytes. Arch Biochem Biophys 1993 Apr 2
7 8572289 Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability. Anal Biochem 1995 Jun 10 8
8 8852039 Three-minute high-performance liquid chromatographic assay for NMN adenylyltransferase using a 20-mm-long reversed-phase column. J Chromatogr B Biomed Appl 1996 Feb 9 3
9 10390601 Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis. Curr Med Chem 1999 Jul 1
10 11248244 Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis. FEBS Lett 2001 Mar 9 5
11 11751893 Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis. J Biol Chem 2002 Mar 8 6
12 11752792 Crystallization and preliminary X-ray analysis of human nicotinamide mononucleotide adenylyltransferase (NMNAT). Acta Crystallogr D Biol Crystallogr 2002 Jan 6
13 11788603 Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. J Biol Chem 2002 Apr 12 10
14 11959140 Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN. FEBS Lett 2002 Apr 10 2
15 11966438 Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase. Curr Med Chem 2002 Apr 13
16 11966442 Metabolism of the novel IMP dehydrogenase inhibitor benzamide riboside. Curr Med Chem 2002 Apr 3
17 12117413 A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity. Biochem J 2002 Oct 1 2
18 14516279 Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas. Biochem J 2004 Jan 15 5
19 14565298 Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation. Nucleosides Nucleotides Nucleic Acids 2003 May-Aug 2
20 15078171 Structure and function of nicotinamide mononucleotide adenylyltransferase. Curr Med Chem 2004 Apr 3
21 16118205 Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J Biol Chem 2005 Oct 28 6
22 16247974 Synthesis and biological evaluation of NAD analogs as human pyridine nucleotide adenylyltransferase inhibitors. Nucleosides Nucleotides Nucleic Acids 2005 2
23 16371511 The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Mol Biol Cell 2006 Mar 1
24 16857098 NAD+ metabolism in lymphocytes of patients affected by B-cell chronic lymphocytic leukaemia. Int J Immunopathol Pharmacol 2004 Sep-Dec 6
25 17402747 Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Biochemistry 2007 Apr 24 4
26 18275811 Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism. Structure 2008 Feb 2
27 19355893 NAD(P) biosynthesis enzymes as potential targets for selective drug design. Curr Med Chem 2009 1
28 19403820 Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J Neurosci 2009 Apr 29 2
29 19448972 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme. Cell Mol Life Sci 2009 Sep 3
30 19478080 Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters. J Biol Chem 2009 Jul 24 5
31 19879981 SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochim Biophys Acta 2010 Aug 2
32 20388704 Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. J Biol Chem 2010 Jun 11 2
33 20457531 Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells. Blood Cells Mol Dis 2010 Jun 15 4
34 20591898 Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis. J Exp Bot 2010 Aug 7
35 20954240 Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship. Protein Sci 2010 Dec 4
36 21071441 Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons. J Biol Chem 2010 Dec 31 2
37 21517775 NMN/NaMN adenylyltransferase (NMNAT) and NAD kinase (NADK) inhibitors: chemistry and potential therapeutic applications. Curr Med Chem 2011 4
38 21517776 NMNAT expression and its relation to NAD metabolism. Curr Med Chem 2011 9
39 22334709 Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase. J Biol Chem 2012 Apr 6 3
40 22842227 NMNAT1 mutations cause Leber congenital amaurosis. Nat Genet 2012 Sep 4
41 22842229 Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy. Nat Genet 2012 Sep 2
42 22842230 Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration. Nat Genet 2012 Sep 1
43 23737528 The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. J Biol Chem 2013 Jul 19 3
44 24155910 Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria. PLoS One 2013 2
45 24787896 Axonal transport plays a crucial role in mediating the axon-protective effects of NmNAT. Neurobiol Dis 2014 Aug 1
46 26018082 Characterization of Leber Congenital Amaurosis-associated NMNAT1 Mutants. J Biol Chem 2015 Jul 10 1
47 28445802 NMNAT: It's an NAD<sup>+</sup> synthase… It's a chaperone… It's a neuroprotector. Curr Opin Genet Dev 2017 Jun 2
48 29029387 The β-NAD<sup>+</sup> salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation. Oncotarget 2017 Sep 12 2
49 29748257 Metabolic regulation of transcription through compartmentalized NAD<sup>+</sup> biosynthesis. Science 2018 May 11 2
50 30166529 Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation. Cell Death Dis 2018 Aug 30 3