Janus kinase 2 ; Mus musculus






693 Article(s)
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1 7473055 [Structure and function of IL-5 receptor]. Yakugaku Zasshi 1995 Aug 4
2 7515493 Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants. Proc Natl Acad Sci U S A 1994 Jun 7 5
3 7534285 The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl. J Biol Chem 1995 Mar 10 2
4 7535764 Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation. J Biol Chem 1995 Mar 31 1
5 7539888 Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling. Mol Endocrinol 1995 Mar 1
6 7544789 Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. J Biol Chem 1995 Sep 1 1
7 7580936 Characterization of growth hormone-induced tyrosine-phosphorylated proteins in mouse cells that express GH receptors. Receptor 1995 Summer 1
8 7637029 Inhibition of protein phosphorylation modulates expression of the Jak family protein tyrosine kinases. J Virol 1995 Sep 1
9 7657825 Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells. J Clin Invest 1995 Sep 1
10 7935454 A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction. Mol Cell Biol 1994 Nov 1
11 8007943 Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 1994 Jul 1
12 8013458 Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells. EMBO J 1994 Jun 1 2
13 8134389 Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130. Proc Natl Acad Sci U S A 1994 Mar 15 2
14 8174677 Identification of a 130-kilodalton tyrosine-phosphorylated protein induced by interleukin-11 as JAK2 tyrosine kinase, which associates with gp130 signal transducer. Exp Hematol 1994 May 2
15 8378315 Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci U S A 1993 Sep 15 2
16 8657151 Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 1996 Apr 1
17 8695792 A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines. Blood 1996 Jul 15 1
18 8702683 Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor. J Biol Chem 1996 Aug 16 1
19 8758906 P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation. Cancer Res 1996 Aug 1 1
20 8943308 Association of JAK2 and STAT5 with erythropoietin receptors. Role of receptor phosphorylation in erythropoietin signal transduction. J Biol Chem 1996 Dec 13 2
21 8943354 Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol Cell Biol 1996 Dec 2
22 8977232 Physical and functional interactions between Stat5 and the tyrosine-phosphorylated receptors for erythropoietin and interleukin-3. Blood 1996 Dec 15 1
23 9002950 Thrombopoietin signal transduction in purified murine megakaryocytes. Blood 1997 Jan 15 1
24 9006890 Constitutive activation of JAK1 in Src-transformed cells. J Biol Chem 1997 Jan 31 2
25 9052992 Regulation of the erythropoietin receptor and involvement of JAK2 in differentiation of J2E erythroid cells. Cell Growth Differ 1996 Apr 3
26 9111009 Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins. J Biol Chem 1997 Apr 25 1
27 9121492 Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation. Mol Endocrinol 1996 Oct 5
28 9139679 The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells. J Biol Chem 1997 May 9 1
29 9188787 Microinjected cDNA encoding JAK2 protein-tyrosine kinase induces DNA synthesis in NIH 3T3 cells. FEBS Lett 1997 May 26 2
30 9192755 Erythropoietin induces tyrosine phosphorylation of the interleukin-3 receptor beta subunit (betaIL3) and recruitment of Stat5 to possible Stat5-docking sites in betaIL3. Blood 1997 Jun 15 2
31 9231797 Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B. Endocrinology 1997 Aug 4
32 9310478 Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. Blood 1997 Sep 15 1
33 9343427 Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling. Mol Cell Biol 1997 Nov 10
34 9344843 Erythropoietin and IL-3 induce tyrosine phosphorylation of CrkL and its association with Shc, SHP-2, and Cbl in hematopoietic cells. Biochem Biophys Res Commun 1997 Oct 20 1
35 9359406 Phosphorylation of erythropoietin receptors in the endoplasmic reticulum by pervanadate-mediated inhibition of tyrosine phosphatases. Biochem J 1997 Oct 15 3
36 9389692 Signaling functions of the tyrosine residues in the betac chain of the granulocyte-macrophage colony-stimulating factor receptor. Blood 1997 Dec 15 3
37 9414269 A truncated isoform of the human beta chain common to the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 with increased mRNA expression in some patients with acute leukemia. Blood 1998 Jan 1 1
38 9419340 Nitric oxide and thiol redox regulation of Janus kinase activity. Proc Natl Acad Sci U S A 1998 Jan 6 4
39 9419812 Signalling mechanisms in erythropoiesis: the enigmatic role of calcium. Cell Signal 1997 Nov 1
40 9442080 Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling. J Biol Chem 1998 Jan 23 1
41 9447970 Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor. Mol Cell Biol 1998 Feb 3
42 9458105 Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line. Cancer Res 1998 Feb 1 3
43 9488432 Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cells. Mol Cell Biol 1998 Mar 2
44 9510175 Induction of Jak/STAT signaling by activation of the type 1 TNF receptor. J Immunol 1998 Mar 15 1
45 9528973 Lactogenic hormone-inducible phosphorylation and gamma-activated site-binding activities of Stat5b in primary rat Leydig cells and MA-10 mouse Leydig tumor cells. Endocrinology 1998 Apr 1
46 9548458 Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase. J Immunol 1997 Dec 1 1
47 9624169 Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase. J Biol Chem 1998 Jun 19 3
48 9736611 Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J 1998 Sep 15 1
49 9843570 Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the coumermycin/gyrase B system. Mol Biol Cell 1998 Dec 3
50 10218944 Insulin receptor substrate-1 enhances growth hormone-induced proliferation. Endocrinology 1999 May 3