cholinergic receptor nicotinic alpha 4 subunit ; Homo sapiens






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1 1384491 Roles of the aromatic residues in cobrotoxin in antigenicity and binding activity to nicotinic acetylcholine receptor. Biochem Int 1992 Jul 3
2 1385107 The roles of serine and threonine sidechains in ion channels: a modelling study. Eur Biophys J 1992 2
3 1397309 Ligand-activated ion channels may share common gating mechanisms with the Shaker potassium channel. FEBS Lett 1992 Oct 19 2
4 1465217 Nicotinic acetylcholine receptors in human neuroblastoma (SH-SY5Y) cells. Neurosci Lett 1992 Oct 12 5
5 1505686 Fourier transform infrared (FTIR) spectroscopic investigation of the nicotinic acetylcholine receptor (nAChR). Investigation of agonist binding and receptor conformational changes by flash-induced release of 'caged' carbamoylcholine. FEBS Lett 1992 Sep 7 3
6 1517779 Conformational studies on (+)-anatoxin-a and derivatives. J Comput Aided Mol Des 1992 Jun 4
7 1581507 Incorporation of the nicotinic acetylcholine receptor into planar multilamellar films: characterization by fluorescence and Fourier transform infrared difference spectroscopy. Biophys J 1992 Apr 1
8 1592722 Tolerance and upregulation of acetylcholine receptors follow chronic infusion of d-tubocurarine. J Appl Physiol (1985) 1992 Apr 2
9 1651933 Purification and characterization of a protein tyrosine phosphatase which dephosphorylates the nicotinic acetylcholine receptor. J Biol Chem 1991 Aug 25 8
10 1715611 MK-801 inhibition of nicotinic acetylcholine receptor channels. Synapse 1991 Mar 1
11 1740234 Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors. FASEB J 1992 Feb 1 1
12 1910671 Pharmacological specificity of a nicotinic acetylcholine receptor optical sensor. Biosens Bioelectron 1991 10
13 1979446 The role of tyrosine at the ligand-binding site of the nicotinic acetylcholine receptor. Proc Biol Sci 1990 Sep 22 2
14 2002334 Effects of chronic nicotinic ligand exposure on functional activity of nicotinic acetylcholine receptors expressed by cells of the PC12 rat pheochromocytoma or the TE671/RD human clonal line. J Neurochem 1991 Apr 9
15 2049167 Effects of receptor concentration, media pH and storage on nicotinic receptor-transmitted signal in a fiber-optic biosensor. Biosens Bioelectron 1991 2
16 2099742 Modelling of binding sites of the nicotinic acetylcholine receptor and their relation to models of the whole receptor. Biochem Soc Symp 1990 4
17 2209600 Expression and characterization of the chick nicotinic acetylcholine receptor alpha-subunit in insect cells using a baculovirus vector. Eur J Biochem 1990 Sep 11 1
18 2475163 Interaction of nicotinic acetylcholine receptor with two monoclonal antibodies recognizing different epitopes. Biochemistry 1989 May 16 2
19 2514612 Acetylcholine receptor fiber-optic evanescent fluorosensor. Anal Biochem 1989 Nov 1 9
20 7473192 Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain. J Pharmacol Exp Ther 1995 Nov 6
21 7480004 Cholinergic channel activators: novel opportunities for the treatment of CNS disorders. Proc West Pharmacol Soc 1995 2
22 7490259 Determination of soluble nAChR-binding activity of alpha-neurotoxins by an innovative precipitation with DEAE-Sephacel. J Biochem 1995 Jun 1
23 7493938 Fourier transform infrared and hydrogen/deuterium exchange reveal an exchange-resistant core of alpha-helical peptide hydrogens in the nicotinic acetylcholine receptor. J Biol Chem 1995 Dec 8 15
24 7516704 Secondary structure of the nicotinic acetylcholine receptor: implications for structural models of a ligand-gated ion channel. Biochemistry 1994 Jun 21 6
25 7541791 The structural loop II of cobrotoxin is the main binding region for nAChR and epitope in the region is conformation-dependent. J Biochem 1995 Feb 5
26 7566493 Human alpha 7 nicotinic acetylcholine receptor responses to novel ligands. Neuropharmacology 1995 Jun 2
27 7578128 Structure of both the ligand- and lipid-dependent channel-inactive states of the nicotinic acetylcholine receptor probed by FTIR spectroscopy and hydrogen exchange. Biochemistry 1995 Nov 21 4
28 7637783 Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature 1995 Aug 10 1
29 7693004 Channel blocking properties of a series of nicotinic cholinergic agonists. Biophys J 1993 Aug 1
30 7696505 alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophys J 1995 Feb 2
31 7715858 Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways. Neurotoxicology 1994 Winter 6
32 7756343 Snake venom toxins, unlike smaller antagonists, appear to stabilize a resting state conformation of the nicotinic acetylcholine receptor. Biochim Biophys Acta 1995 May 4 5
33 7913497 (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization. J Pharmacol Exp Ther 1994 Jul 9
34 7950973 Distribution of neuronal nicotinic receptor subunits in human brain. Neurochem Int 1994 Jul 2
35 7957916 Functional expression of nicotinic acetylcholine receptors containing rat alpha 7 subunits in human SH-SY5Y neuroblastoma cells. FEBS Lett 1994 Nov 7 1
36 7961707 Protein-tyrosine phosphatases specifically regulate muscle adult-type nicotinic acetylcholine receptor gene expression. J Biol Chem 1994 Nov 11 1
37 7963258 Mechanism of long-lasting block of ganglion nicotinic receptors by mono-ammonium compounds with long aliphatic chain. J Auton Nerv Syst 1994 Aug 2
38 7984036 Cellular distribution of nicotinic acetylcholine receptor subunit mRNAs in the human cerebral cortex as revealed by non-isotopic in situ hybridization. Brain Res Mol Brain Res 1994 Aug 1
39 8011898 Transverse distance between the membrane and the agonist binding sites on the Torpedo acetylcholine receptor: a fluorescence study. Biophys J 1994 Mar 1
40 8038129 Nicotinic acetylcholine receptors in the ground squirrel retina: localization of the beta 4 subunit by immunohistochemistry and in situ hybridization. Vis Neurosci 1994 May-Jun 2
41 8241115 NMR solution structure of an alpha-bungarotoxin/nicotinic receptor peptide complex. Biochemistry 1993 Nov 23 2
42 8360687 Cytochalasin modulation of nicotinic cholinergic receptor expression and muscarinic receptor function in human TE671/RD cells: a possible functional role of the cytoskeleton. J Neurochem 1993 Sep 8
43 8474012 Expression of ganglia-type nicotinic acetylcholine receptors and nicotinic ligand binding sites by cells of the IMR-32 human neuroblastoma clonal line. J Pharmacol Exp Ther 1993 Apr 4
44 8510190 Neurobehavioral mechanisms of nicotine action: role in the initiation and maintenance of tobacco dependence. J Subst Abuse Treat 1993 Mar-Apr 1
45 8516349 Nicotinic and nonnicotinic receptor-mediated actions of vinblastine. Proc Soc Exp Biol Med 1993 Jul 7
46 8531111 The "calcium antagonist" TMB-8 [3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester] is a potent, non-competitive, functional antagonist at diverse nicotinic acetylcholine receptor subtypes. J Pharmacol Exp Ther 1995 Dec 12
47 8558445 Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor. J Pharmacol Exp Ther 1996 Jan 7
48 8567173 Role of amino and carboxyl groups of cobrotoxin in the conformational stability and the interaction with acetylcholine receptor. Int J Pept Protein Res 1995 Aug 3
49 8610122 An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A 1996 Apr 2 8
50 8738758 Nicotinic receptor subunits alpha 3, alpha 4, and beta 2 and high affinity nicotine binding sites are expressed by P19 embryonal cells. J Neurobiol 1996 Jun 4