angiopoietin like 4 ; Homo sapiens






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1 14570927 Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4. J Biol Chem 2004 Jan 16 1
2 15190076 The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J Biol Chem 2004 Aug 13 6
3 15837923 Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A 2005 Apr 26 1
4 15863837 Differential regulation and properties of angiopoietin-like proteins 3 and 4. J Lipid Res 2005 Jul 1
5 16805838 High glucose-induced activation of the polyol pathway and changes of gene expression profiles in immortalized adult mouse Schwann cells IMS32. J Neurochem 2006 Jul 1
6 16870142 Insulin downregulates angiopoietin-like protein 4 mRNA in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2006 Sep 8 2
7 17049073 Is oxygen a key factor in the lipodystrophy phenotype? Lipids Health Dis 2006 Oct 18 1
8 17068295 Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton. Circ Res 2006 Nov 24 2
9 17322881 Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet 2007 Apr 2
10 18054822 Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. Toxicology 2008 Jan 14 2
11 18177513 The PPARgamma ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARgamma in the subcutaneous adipose tissue. Br J Nutr 2008 Mar 1
12 18223235 In vivo and microarray analysis of rexinoid-responsive anaplastic thyroid carcinoma. Clin Cancer Res 2008 Jan 15 1
13 18466728 [Gut microflora is a key player in host energy homeostasis]. Med Sci (Paris) 2008 May 1
14 18599063 Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study. Atherosclerosis 2009 Mar 6
15 18634015 Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation. J Orthop Res 2009 Jan 1
16 18809343 Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study. Ann Epidemiol 2008 Nov 5
17 18940399 Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Metabolism 2008 Nov 1
18 18974381 ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk. Arterioscler Thromb Vasc Biol 2008 Dec 1
19 19019854 Interaction of the coiled-coil domain with glycosaminoglycans protects angiopoietin-like 4 from proteolysis and regulates its antiangiogenic activity. FASEB J 2009 Mar 3
20 19028676 The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms. J Biol Chem 2009 Jan 16 4
21 19074989 Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. Diabetes 2009 Mar 2
22 19075393 Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest 2009 Jan 1
23 19270337 Genetic variation in ANGPTL4 provides insights into protein processing and function. J Biol Chem 2009 May 8 4
24 19342599 Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids. Arterioscler Thromb Vasc Biol 2009 Jun 5
25 19851103 Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events. Curr Opin Lipidol 2010 Feb 2
26 19903832 15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist. Mol Pharmacol 2010 Feb 2
27 20025870 Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways. Exp Cell Res 2010 Feb 15 5
28 20056168 Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1. Biochim Biophys Acta 2010 Apr 1
29 20667978 Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. FASEB J 2010 Dec 1
30 20972945 Serum levels of the adipokine fasting-induced adipose factor/angiopoietin-like protein 4 depend on renal function. Horm Metab Res 2011 Feb 6
31 21085648 An evolutionary framework for association testing in resequencing studies. PLoS Genet 2010 Nov 11 1
32 21109185 Fat-induced inflammation unchecked. Cell Metab 2010 Dec 1 4
33 21182758 Gene expression profiling of subcutaneous adipose tissue in morbid obesity using a focused microarray: distinct expression of cell-cycle- and differentiation-related genes. BMC Med Genomics 2010 Dec 23 2
34 21206970 PPAR╬│ is functionally expressed in clear cell renal cell carcinoma. Int J Oncol 2011 Mar 1
35 21397852 Escaping Anoikis through ROS: ANGPTL4 controls integrin signaling through Nox1. Cancer Cell 2011 Mar 8 2
36 21397862 Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors. Cancer Cell 2011 Mar 8 6
37 21398697 Proteolytic processing of angiopoietin-like protein 4 by proprotein convertases modulates its inhibitory effects on lipoprotein lipase activity. J Biol Chem 2011 May 6 2
38 21518214 Bacterial monocultures, propionate, butyrate and H2O2 modulate the expression, secretion and structure of the fasting-induced adipose factor in gut epithelial cell lines. Environ Microbiol 2011 Jul 8
39 21615395 In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor ╬┤ reflects donors' insulin sensitivity in vivo. Eur J Clin Invest 2011 Dec 3
40 21646389 Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly. Diabetes 2011 Aug 1
41 21709421 Fatty acids and hypoxia stimulate the expression and secretion of the adipokine ANGPTL4 (angiopoietin-like protein 4/ fasting-induced adipose factor) by human adipocytes. J Nutrigenet Nutrigenomics 2011 9
42 21714923 ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial. BMC Med Genet 2011 Jun 29 8
43 21725974 Genome-wide transcriptional profiling analysis of all trans retinoic acid-treated tongue carcinoma SCC-9 cells. J Surg Oncol 2011 Dec 1
44 21741084 Docosahexaenoic acid stimulates tube formation in first trimester trophoblast cells, HTR8/SVneo. Placenta 2011 Sep 1
45 21860410 HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. Oncogene 2012 Apr 5 2
46 21937683 ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. Cancer Res 2011 Nov 15 6
47 21966511 Angiopoietin-like 4 regulates epidermal differentiation. PLoS One 2011 1
48 21974967 New insights into human minimal change disease: lessons from animal models. Am J Kidney Dis 2012 Feb 6
49 22063269 Regulation of triglyceride metabolism by Angiopoietin-like proteins. Biochim Biophys Acta 2012 May 5
50 22078753 Effects of hyperinsulinemia on lipoprotein lipase, angiopoietin-like protein 4, and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 in subjects with and without type 2 diabetes mellitus. Metabolism 2012 May 1