carbonic anhydrase 5A ; Homo sapiens






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1 8356065 Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16. Proc Natl Acad Sci U S A 1993 Aug 15 1
2 9398305 Glutamate and aspartate as proton shuttles in mutants of carbonic anhydrase. Biochemistry 1997 Dec 16 8
3 9523771 Development and pharmacological characterization of a modified procedure for the measurement of carbonic anhydrase activity. J Pharmacol Toxicol Methods 1997 Nov 2
4 9805254 Improved oxygen utilization during mild exercise in heart failure. Jpn Circ J 1998 Oct 3
5 10082753 Cell-specific expression of mitochondrial carbonic anhydrase in the human and rat gastrointestinal tract. J Histochem Cytochem 1999 Apr 2
6 10409679 Human mitochondrial carbonic anhydrase VB. cDNA cloning, mRNA expression, subcellular localization, and mapping to chromosome x. J Biol Chem 1999 Jul 23 1
7 10768298 Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 2000 2
8 11140614 Carbonic anhydrase inhibitors: aromatic sulfonamides and disulfonamides act as efficient tumor growth inhibitors. J Enzyme Inhib 2000 2
9 11203012 Carbonic anhydrase inhibitors--Part 94. 1,3,4-thiadiazole-2-sulfonamidederivatives as antitumor agents? Eur J Med Chem 2000 Sep 1
10 11310605 Carbonic anhydrase inhibitors: sulfonamides as antitumor agents? Bioorg Med Chem 2001 Mar 1
11 11928941 Pathogenic mechanism, prophylaxis, and therapy of symptomatic acidosis induced by acetazolamide. J Investig Med 2002 Mar 2
12 12142734 Immunohistochemical localization of pyruvate carboxylase and carbamyl-phosphate synthetase I in normal and neoplastic human pancreatic tissues. Pancreas 2002 Aug 1
13 15482952 Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. Bioorg Med Chem Lett 2004 Nov 15 2
14 15501037 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorg Med Chem Lett 2004 Dec 6 7
15 15501038 Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. Bioorg Med Chem Lett 2004 Dec 6 4
16 15633752 Dicarboxylic degradation products of nonylphenol polyethoxylates: synthesis and identification by gas chromatography-mass spectrometry using electron and chemical ionization modes. J Chromatogr A 2004 Dec 17 4
17 15637154 Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides. Proc Natl Acad Sci U S A 2005 Jan 18 9
18 15664815 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett 2005 Feb 1 1
19 16203142 Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides. Bioorg Med Chem Lett 2005 Dec 1 2
20 16686544 Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design. J Med Chem 2006 May 18 2
21 17125255 Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue. J Med Chem 2006 Nov 30 2
22 17420132 Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA. Bioorg Med Chem 2007 Jun 15 4
23 18184831 Design of mutant beta2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells. J Pharmacol Exp Ther 2008 Apr 1
24 18242985 Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV). Bioorg Med Chem Lett 2008 Mar 1 1
25 18990571 Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. Bioorg Med Chem Lett 2008 Dec 15 2
26 19095299 The adsorption of preferential binding peptides to apatite-based materials. Biomaterials 2009 Mar 1
27 19237593 Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation. J Gen Physiol 2009 Mar 2
28 19539481 Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB. Bioorg Med Chem 2009 Jul 15 2
29 19962903 Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library. Bioorg Med Chem 2010 Jan 1 1
30 21300547 (R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases. Bioorg Med Chem Lett 2011 Mar 1 1
31 22299576 Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem 2013 Apr 1
32 22308488 Membrane-localized β-subunits alter the PIP2 regulation of high-voltage activated Ca2+ channels. Proc Natl Acad Sci U S A 2012 Feb 21 3
33 22442573 Regulation of presynaptic strength by controlling Ca2+ channel mobility: effects of cholesterol depletion on release at the cone ribbon synapse. J Neurophysiol 2012 Jun 5
34 22624680 Inhibition of human recombinant T-type calcium channels by N-arachidonoyl 5-HT. Br J Pharmacol 2012 Nov 5
35 22825404 The North Atlantic Oscillation affects the quality of Cava (Spanish sparkling wine). Int J Biometeorol 2013 May 6
36 23382808 Functional roles of the non-catalytic calcium-binding sites in the N-terminal domain of human peptidylarginine deiminase 4. PLoS One 2013 2
37 24012377 Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition. Bioorg Med Chem 2013 Nov 1 1
38 26004220 First-principles calculations of divalent substitution of Ca(2+) in tricalcium phosphates. Acta Biomater 2015 Sep 3
39 26421381 Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea. J Biomol Struct Dyn 2016 Sep 3
40 26805098 [Survival after Sorafenib Treatment for Advanced Recurrent Hepatocellular Carcinoma with Tumor Thrombus in the Inferior Vena Cava]. Gan To Kagaku Ryoho 2015 Nov 1
41 26913920 Defective hepatic bicarbonate production due to carbonic anhydrase VA deficiency leads to early-onset life-threatening metabolic crisis. Genet Med 2016 Oct 1
42 27365118 GdnHCl-induced unfolding intermediate in the mitochondrial carbonic anhydrase VA. Int J Biol Macromol 2016 Oct 8
43 28131914 Regulation of high glucose-induced apoptosis of brain pericytes by mitochondrial CA VA: A specific target for prevention of diabetic cerebrovascular pathology. Biochim Biophys Acta Mol Basis Dis 2017 Apr 2
44 28277280 Bortezomib inhibits mammalian carbonic anhydrases. Bioorg Med Chem 2017 Oct 1 1
45 28330086 Cloning, expression, purification and characterization of human mitochondrial carbonic anhydrase VA. 3 Biotech 2016 Jun 7
46 28936885 Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII. J Enzyme Inhib Med Chem 2017 Dec 1
47 29129580 The β and α2δ auxiliary subunits of voltage-gated calcium channel 1 (Ca<sub>v</sub>1) are required for T<sub>H</sub>2 lymphocyte function and acute allergic airway inflammation. J Allergy Clin Immunol 2018 Sep 4
48 29305297 Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors. Bioorg Med Chem 2018 Feb 1 1
49 29701427 Heparin Resistance During Surgical Resection of Inferior Vena Cava and Right Atrial Tumor Thrombus: A Case Report. Rev Port Cir Cardiotorac Vasc 2017 Jul-Dec 2
50 30216643 Near-infrared emitting Ca<sub>5</sub> (PO<sub>4</sub> )<sub>3</sub> Cl:Eu<sup>2+</sup> ,Nd<sup>3+</sup> phosphor for modification of the solar spectrum. Luminescence 2018 Nov 2