polyribonucleotide nucleotidyltransferase 1 ; Homo sapiens






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1 108675 Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: genetic model for immunodeficiency disease. Proc Natl Acad Sci U S A 1979 Mar 2
2 824697 [Purification of purine nucleoside phosphorylase activity on deoxyinosine (author's transl)]. Rev Esp Fisiol 1976 Sep 2
3 1109594 Purine nucleoside phosphorylase. Microheterogeneity and comparison of kinetic behavior of the enzyme from several tissues and species. Biochemistry 1975 Jan 14 5
4 1908235 Selective in vitro inhibition of human MOLT-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972. Biochem Biophys Res Commun 1991 Aug 15 3
5 1909177 Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase. Biochemistry 1991 Aug 27 7
6 2114620 Purine nucleoside phosphorylase: purification using an ether-linked formycin B/sepharose 6B resin with unusual properties. Prep Biochem 1990 3
7 3157330 Enzymatic synthesis of uniformly 32P-labeled polyribonucleotides and high-specific-activity ribonucleoside 5'-[alpha-32P]diphosphates. Anal Biochem 1985 Jan 3
8 6090133 Enzymatic activities in thylakoid membranes, which form medium [32P]NDP and [32P]ATP from 32Pi. Polynucleotide phosphorylase and adenylate kinase. Eur J Biochem 1984 Sep 17 6
9 6097591 Synthesis and protective effects of poly-8-bromoriboadenylic acid: poly ribouridylic acid hybrid against Wesselsbron virus in chick embryos. J Biochem 1984 Oct 8
10 8632418 Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase. J Med Chem 1996 Feb 16 4
11 8662001 De Novo Synthesis of DNA-Like Molecules by Polynucleotide Phosphorylase In Vitro J Mol Evol 1996 May 19
12 8810258 Nucleotides reveal polynucleotide phosphorylase activity from conventionally purified GroEL. J Biol Chem 1996 Oct 11 1
13 9211914 The mechanism of preferential degradation of polyadenylated RNA in the chloroplast. The exoribonuclease 100RNP/polynucleotide phosphorylase displays high binding affinity for poly(A) sequence. J Biol Chem 1997 Jul 11 2
14 10222010 Photometric assay for polynucleotide phosphorylase. Anal Biochem 1999 May 1 7
15 15210334 Cooperation of endo- and exoribonucleases in chloroplast mRNA turnover. Prog Nucleic Acid Res Mol Biol 2004 7
16 15492272 Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation. Cancer Res 2004 Oct 15 5
17 15769737 Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase. J Biol Chem 2005 May 20 1
18 15978720 Molecular mechanisms of aging-associated inflammation. Cancer Lett 2006 May 8 4
19 16525558 Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases. Org Biomol Chem 2006 Mar 21 2
20 17084501 Genetic analysis of polynucleotide phosphorylase structure and functions. Biochimie 2007 Jan 2
21 18083836 Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts. RNA 2008 Feb 2
22 18501193 Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress. Biochem Biophys Res Commun 2008 Jul 25 2
23 19509288 Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality. J Biol Chem 2009 Jul 31 2
24 20457661 Polynucleotide phosphorylase and mitochondrial ATP synthase mediate reduction of arsenate to the more toxic arsenite by forming arsenylated analogues of ADP and ATP. Toxicol Sci 2010 Oct 32
25 22815474 Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776. J Biol Chem 2012 Sep 7 3
26 23084291 Mutation in PNPT1, which encodes a polyribonucleotide nucleotidyltransferase, impairs RNA import into mitochondria and causes respiratory-chain deficiency. Am J Hum Genet 2012 Nov 2 1
27 23319881 Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction. Archaea 2012 5
28 24143183 Identification of genes potentially regulated by human polynucleotide phosphorylase (hPNPase old-35) using melanoma as a model. PLoS One 2013 1
29 24729470 Analysis of global changes in gene expression induced by human polynucleotide phosphorylase (hPNPase(old-35)). J Cell Physiol 2014 Dec 2
30 24770417 Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. J Biol Chem 2014 Jun 13 2
31 28594066 Novel biallelic mutations in the PNPT1 gene encoding a mitochondrial-RNA-import protein PNPase cause delayed myelination. Clin Genet 2018 Feb 1
32 31752325 Clinical Spectrum and Functional Consequences Associated with Bi-Allelic Pathogenic <i>PNPT1</i> Variants. J Clin Med 2019 Nov 19 2
33 31988703 Computational evolution of an RNA-binding protein towards enhanced oxidized-RNA binding. Comput Struct Biotechnol J 2020 2
34 31995710 Nonspherical Coacervate Shapes in an Enzyme-Driven Active System. Langmuir 2020 Mar 3 1
35 32540202 Novel PNPT1-ALK fusion variant exerted significant benefit to crizotinib in NSCLC. Lung Cancer 2020 Aug 1
36 32809827 A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem 2020 Sep 10 1
37 33158637 PNPT1 mutations may cause Aicardi-Goutières-Syndrome. Brain Dev 2021 Feb 1
38 34074335 Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis. Diabetol Metab Syndr 2021 Jun 1 2