ATP-binding cassette, sub-family B (MDR/TAP), member 1B ; Mus musculus






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1 1352414 Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science 1992 Jul 3 1
2 1352702 Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug resistance profiles. Biochemistry 1992 Jul 7 1
3 1356238 Adaptation of mouse leukemia cells L1210 to vincristine. Evidence for expression of P-glycoprotein. Neoplasma 1992 2
4 1357667 Transfer and expression of the human multiple drug resistance gene into live mice. Proc Natl Acad Sci U S A 1992 Oct 15 10
5 1363885 Down-regulation of ras and myc expression associated with mdr-1 overexpression in adriamycin-resistant tumor cells. Cell Mol Biol 1992 Sep 1
6 1371401 Lipophilic cations: a group of model substrates for the multidrug-resistance transporter. Biochemistry 1992 Feb 25 8
7 1671173 Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance. Proc Natl Acad Sci U S A 1991 Jan 15 3
8 1671863 Full length and alternatively spliced pgp1 transcripts in multidrug-resistant Chinese hamster lung cells. J Biol Chem 1991 Mar 5 1
9 1675425 A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs. Mol Cell Biol 1991 Jul 3
10 1676579 Time course of MDR gene amplification during in vivo selection for doxorubicin-resistance and during reversal in murine leukemia L 1210. Anticancer Res 1991 Mar-Apr 2
11 1677815 Implantation of recombinant rat myocytes into adult skeletal muscle: a potential gene therapy. Hum Gene Ther 1991 Spring 1
12 1678520 A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps. Proc Natl Acad Sci U S A 1991 Aug 15 8
13 1737094 Transplantation of bone marrow cells from transgenic mice expressing the human MDR1 gene results in long-term protection against the myelosuppressive effect of chemotherapy in mice. Blood 1992 Feb 15 2
14 1868977 Molecular manipulations of the multidrug transporter: a new role for transgenic mice. FASEB J 1991 Aug 3
15 1968358 Cellular and biochemical characterization of thioxanthenes for reversal of multidrug resistance in human and murine cell lines. Cancer Res 1990 Mar 15 4
16 1972378 Differential transport properties of two mdr gene products are distinguished by progesterone. J Biol Chem 1990 Jun 25 1
17 1980424 Structural and functional characterization of the mouse multidrug resistance gene family. Bull Cancer 1990 3
18 1983720 Structure and function of P-glycoprotein in the normal liver and intestine. Princess Takamatsu Symp 1990 4
19 2069718 Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin. DNA Cell Biol 1991 Jul-Aug 4
20 2304382 The products of the mdr1a and mdr1b genes from multidrug resistant murine cells have similar degradation rates. Life Sci 1990 1
21 2473069 Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes. J Biol Chem 1989 Jul 15 1
22 2565763 Characterization of the multidrug resistance protein expressed in cell clones stably transfected with the mouse mdr1 cDNA. Cancer Res 1989 May 15 2
23 2567301 The multidrug transporter: rapid modulation of efflux activity monitored in single cells by the morphologic effects of vinblastine and daunomycin. J Histochem Cytochem 1989 Jul 2
24 2573836 Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance. Mol Cell Biol 1989 Dec 3
25 2790781 Influence of microenvironmental pH on adriamycin resistance. Cancer Res 1989 Oct 15 1
26 2825978 Partial reversal of doxorubicin resistance by forskolin and 1,9-dideoxyforskolin in murine sarcoma S180 variants. Cancer Res 1988 Feb 1 3
27 7628053 Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833. Cancer Chemother Pharmacol 1995 1
28 7634376 Relationship between multidrug resistant gene expression and multidrug resistant-reversing effect of MS-209 in various tumor cells. Cancer Chemother Pharmacol 1995 2
29 7654009 Structurally modified anthracyclines retain activity in a cell line with simultaneous typical and atypical multidrug resistance. Anticancer Res 1995 Jul-Aug 1
30 7654329 Expression of the mdr1 P-glycoprotein gene: a mechanism of escape from glucocorticoid-induced apoptosis. Biochem Cell Biol 1994 Nov-Dec 1
31 7659186 Decreased sensitivity of multidrug-resistant tumor cells to cisplatin is correlated with sorcin gene co-amplification. Neoplasma 1995 8
32 7682843 Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site. Biochemistry 1993 Apr 27 2
33 7697825 Gene amplification and multidrug resistance induced by the phosphatase-inhibitory tumor promoter, okadaic acid. Carcinogenesis 1995 Mar 1
34 7718262 Comparative study on reversal efficacy of SDZ PSC 833, cyclosporin A and verapamil on multidrug resistance in vitro and in vivo. Acta Oncol 1995 1
35 7734012 Tissue distribution of the human MDR3 P-glycoprotein. Lab Invest 1994 Nov 2
36 7790384 Regulation of multidrug resistance gene mdr1b/mdr1 expression in isolated mouse uterine epithelial cells. J Cell Physiol 1995 Jul 4
37 7841045 Selective photodynamic inactivation of a multidrug transporter by a cationic photosensitising agent. Br J Cancer 1995 Feb 1
38 7847840 Characterization of four drug-resistant P388 sublines: resistance/sensitivity in vivo, resistance-and proliferation-markers, immunogenicity. Anticancer Res 1994 Sep-Oct 1
39 7866993 Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters. Cancer Res 1995 Mar 1 2
40 7896537 Reversal of multidrug resistance in murine fibrosarcoma cells by thioxanthene flupentixol. Invest New Drugs 1994 8
41 7901220 Identification of the major phosphorylation domain of murine mdr1b P-glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites. J Biol Chem 1993 Nov 25 1
42 7903303 Targeted disruption of the mouse mdr1b gene reveals that steroid hormones enhance mdr gene expression. J Biol Chem 1993 Dec 25 5
43 7903407 Effect of multidrug-resistant P-glycoprotein gene expression on chloroaluminum tetrasulfonate phthalocyanine concentration. Lasers Surg Med 1993 1
44 7907953 Functional studies with a full-length P-glycoprotein cDNA encoded by the hamster pgp1 gene. Cancer Chemother Pharmacol 1994 4
45 7909724 Dominant expression of multidrug resistance in intraspecific murine lymphoma hybrid cells. Cancer Chemother Pharmacol 1994 3
46 7910372 Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates. Mol Pharmacol 1994 Apr 12
47 7910854 Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J Natl Cancer Inst 1994 Jun 15 1
48 7911394 Reversal of multidrug resistance by RU 486. Cancer Res 1994 Jun 15 1
49 7911682 Transfection of mu MDR 1 inhibits Na(+)-independent Cl-/-HCO3 exchange in Chinese hamster ovary cells. Biochemistry 1994 Jun 14 1
50 7912874 [Expression of human multidrug resistance gene (mdr1) cDNA in murine ES cells and in chimeric mice]. Shi Yan Sheng Wu Xue Bao 1993 Dec 2