paraoxonase 1 ; Homo sapiens






1242 Article(s)
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1 1650712 Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein. FEBS Lett 1991 Jul 29 1
2 1657140 Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence. Biochemistry 1991 Oct 22 3
3 1661643 Influence of serum paraoxonase polymorphism on serum lipids and apolipoproteins. Clin Genet 1991 Oct 10
4 1690462 Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats. Toxicol Appl Pharmacol 1990 Mar 15 12
5 3914638 Co-localization of neuropeptide tyrosine (NPY) and its C-terminal flanking peptide (C-PON). Peptides 1985 Nov-Dec 1
6 6318563 A study of the polymorphism and ethnic distribution differences of human serum paraoxonase. Am J Phys Anthropol 1983 Nov 1
7 7600118 Multiple genetic determinants of variation of plasma lipoproteins in Alberta Hutterites. Arterioscler Thromb Vasc Biol 1995 Jul 2
8 7638166 Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase. Proc Natl Acad Sci U S A 1995 Aug 1 5
9 7749820 A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate. Arterioscler Thromb Vasc Biol 1995 Jan 7
10 7961970 Carbachol-stimulated phosphorylation of the Na-K-Cl cotransporter of avian salt gland. Requirement for Ca2+ and PKC Activation. J Biol Chem 1994 Nov 25 1
11 8098250 The molecular basis of the human serum paraoxonase activity polymorphism. Nat Genet 1993 Jan 2
12 8382160 Identification of a distinct human high-density lipoprotein subspecies defined by a lipoprotein-associated protein, K-45. Identity of K-45 with paraoxonase. Eur J Biochem 1993 Feb 1 2
13 8565784 Comparison of purified human and rabbit serum paraoxonases. Drug Metab Dispos 1995 Sep 1
14 8661009 The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics 1996 May 1 2
15 8675659 Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. J Clin Invest 1995 Dec 3
16 8812495 Structural organization of the human PON1 gene. Genomics 1996 Aug 1 1
17 8896566 The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat Genet 1996 Nov 2
18 8902155 The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study. Atherosclerosis 1996 Oct 25 8
19 8960946 Paraoxonase gene polymorphism in Japanese subjects with coronary heart disease. Int J Cardiol 1996 Nov 15 2
20 9109446 Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. J Clin Invest 1997 Apr 15 1
21 9215303 Paraoxonase polymorphism (Gln192-Arg) is associated with coronary heart disease in Japanese noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1997 Jul 1
22 9240427 Cigarette smoke extract inhibits plasma paraoxonase activity by modification of the enzyme's free thiols. Biochem Biophys Res Commun 1997 Jul 18 7
23 9313934 Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon. Br J Pharmacol 1997 Sep 3
24 9373189 Presence of paraoxonase in human interstitial fluid. FEBS Lett 1997 Oct 27 1
25 9531524 Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent. Drug Metab Dispos 1998 Apr 1
26 9541487 Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. J Clin Invest 1998 Apr 15 18
27 9591753 Serum paraoxonase activity and its relationship to diabetic complications in patients with non-insulin-dependent diabetes mellitus. Metabolism 1998 May 5
28 9690920 Lack of association between carotid intima-media thickness and paraoxonase gene polymorphism in non-insulin dependent diabetes mellitus. Atherosclerosis 1998 Jun 4
29 9699900 Genetic variation in paraoxonase-1 and paraoxonase-2 is associated with variation in plasma lipoproteins in Alberta Hutterites. Atherosclerosis 1998 Jul 2
30 9703197 Human serum paraoxonase. Gen Pharmacol 1998 Sep 2
31 9711883 Serum paraoxonase activity and genotype distribution in Japanese patients with diabetes mellitus. Intern Med 1998 Jul 2
32 9712341 Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus. Atherosclerosis 1998 Aug 6
33 9739487 Paraoxonase and coronary heart disease. Curr Opin Lipidol 1998 Aug 5
34 9745924 Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism. Neurotoxicology 1998 Aug-Oct 1
35 9746266 Paraoxonase as a risk marker for cardiovascular disease: facts and hypotheses. Clin Chem Lab Med 1998 Jun 9
36 9763534 The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients. Arterioscler Thromb Vasc Biol 1998 Oct 9
37 9763535 Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R. Arterioscler Thromb Vasc Biol 1998 Oct 14
38 9829330 Paraoxonase gene polymorphism and coronary artery disease in Indian subjects. Int J Cardiol 1998 Sep 30 2
39 9862174 The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan. Atherosclerosis 1998 Dec 4
40 9869659 Paraoxonase protection of LDL against peroxidation is independent of its esterase activity towards paraoxon and is unaffected by the Q-->R genetic polymorphism. J Lipid Res 1999 Jan 1
41 10052953 Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities. Biochemistry 1999 Mar 2 20
42 10232833 Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med 1999 Apr 25
43 10373401 Paraoxonase 1 mutations in a Turkish population. Toxicol Appl Pharmacol 1999 Jun 15 4
44 10373407 Association of low PON1 type Q (type A) arylesterase activity with neurologic symptom complexes in Gulf War veterans. Toxicol Appl Pharmacol 1999 Jun 15 1
45 10411705 Paraoxonase polymorphisms are not associated with cardiovascular risk in renal transplant recipients. Kidney Int 1999 Jul 3
46 10421440 Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis. Chem Biol Interact 1999 May 14 8
47 10421441 Tryptophan residue(s) as major components of the human serum paraoxonase active site. Chem Biol Interact 1999 May 14 15
48 10421457 Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase. Chem Biol Interact 1999 May 14 7
49 10421463 Paraoxonase polymorphism in rabbits. Chem Biol Interact 1999 May 14 5
50 10421474 On the physiological role(s) of the paraoxonases. Chem Biol Interact 1999 May 14 2