lactate dehydrogenase A ; Homo sapiens

431 Article(s)
Pub. Date
#Total Relationship(s)
1 1584205 Regulation of the expression of lactate dehydrogenase isozymes in human lymphocytes. Mol Cell Biochem 1992 Mar 25 1
2 1680602 Isoenzyme (lactate dehydrogenase, aspartate aminotransferase) and dipeptidyl peptidase IV activity changes in blood plasma likely indicative of organ involvement due to arterial hypertension. Cor Vasa 1991 1
3 1959923 Genotypic analysis of families with lactate dehydrogenase A (M) deficiency by selective DNA amplification. Hum Genet 1991 Nov 1
4 2861124 Identification of lactate dehydrogenase-M polypeptide translated in vitro from human and mouse tumor cell poly(A)-containing messenger RNA. Int J Biochem 1985 1
5 3707535 Identification of the mouse low-salt-eluting single-stranded DNA-binding protein as a mammalian lactate dehydrogenase-A isoenzyme. Biochem J 1986 Feb 1 2
6 5584002 The determination of lactate dehydrogenase isoenzymes in normal human muscle and other tissues. Biochem J 1967 Nov 1
7 6331099 Cytochemical changes in lactate dehydrogenase isoenzymes in human brain tumours. Acta Neurochir (Wien) 1984 1
8 7619399 Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid. Biotechnol Prog 1995 May-Jun 1
9 7630349 Characterization of the glycolysis in lactate dehydrogenase-A deficiency. Muscle Nerve 1995 Aug 1
10 7986093 Effect of tubulin on the activity of the muscle isoenzyme of lactate dehydrogenase. Arch Biochem Biophys 1994 Dec 5
11 8022811 Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. Proc Natl Acad Sci U S A 1994 Jul 5 1
12 8089148 Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 1994 Sep 23 1
13 8252592 Increased expression of the lactate dehydrogenase M subunit in myocardial regions with decreased thallium uptake. Cardiovasc Res 1993 Jul 1
14 8985143 Removal of substrate inhibition in a lactate dehydrogenase from human muscle by a single residue change. FEBS Lett 1996 Dec 16 2
15 9112394 Tumor necrosis factor-alpha-stimulated lactate production is linked to lactate dehydrogenase A expression and activity increase in porcine cultured Sertoli cells. Endocrinology 1997 May 1
16 9192621 c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc Natl Acad Sci U S A 1997 Jun 24 2
17 9387095 Oncogenes in tumor metabolism, tumorigenesis, and apoptosis. J Bioenerg Biomembr 1997 Aug 1
18 9688541 Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines. FEBS Lett 1998 Jul 3 1
19 9748363 Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. J Med Chem 1998 Sep 24 2
20 9774474 Protein kinase A stimulates binding of multiple proteins to a U-rich domain in the 3'-untranslated region of lactate dehydrogenase A mRNA that is required for the regulation of mRNA stability. J Biol Chem 1998 Oct 23 7
21 10100870 Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression. FEBS Lett 1999 Mar 12 1
22 10385397 Tumor necrosis factor-alpha stimulates lactate dehydrogenase A expression in porcine cultured sertoli cells: mechanisms of action. Endocrinology 1999 Jul 1
23 10491655 Epidermal growth factor regulates glucose metabolism through lactate dehydrogenase A messenger ribonucleic acid expression in cultured porcine Sertoli cells. Biol Reprod 1999 Oct 3
24 10766483 Simple in-line postcolumn oxidation and derivatization for the simultaneous analysis of ascorbic and dehydroascorbic acids in foods. J Chromatogr Sci 2000 Apr 1
25 11058554 Role of sphingosine in the tumor necrosis factor alpha stimulatory effect on lactate dehydrogenase A expression and activity in porcine Sertoli cells. Biol Reprod 2000 Nov 4
26 11286567 Differential expression of lactate dehydrogenase isozymes (LDH) in human placenta with high expression of LDH-A(4) isozyme in the endothelial cells of pre-eclampsia villi. Placenta 2001 Apr 1
27 11513951 Rational selection and quantitative evaluation of antisense oligonucleotides. Biochim Biophys Acta 2001 Aug 30 1
28 12406979 Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line. Clin Chem 2002 Nov 1
29 12555229 Association of an exonic LDHA polymorphism with altered respiratory response in probands at high risk for panic disorder. Am J Med Genet B Neuropsychiatr Genet 2003 Feb 4
30 12963864 The dual role of dexamethasone on anti-inflammation and outflow resistance demonstrated in cultured human trabecular meshwork cells. Mol Vis 2003 Sep 5 2
31 15727167 [Gene expression differences between the anti-BPDE-transformed and normal cells by suppression subtractive hybridization]. Wei Sheng Yan Jiu 2004 Nov 2
32 16098620 Influence of oxygen concentration and pH on expression of hypoxia induced genes. Radiother Oncol 2005 Aug 5
33 16142743 Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint. Arthritis Rheum 2005 Sep 2
34 16198644 A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism. Biochim Biophys Acta 2005 Dec 1 7
35 17512623 Hypoxia induced expression of endogenous markers in vitro is highly influenced by pH. Radiother Oncol 2007 Jun 1
36 17555402 Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem J 2007 Jul 1 9
37 18789002 Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem J 2009 Jan 1 1
38 18828920 D- and L-lactate dehydrogenases during invertebrate evolution. BMC Evol Biol 2008 Oct 1 1
39 19033423 Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol 2009 Aug 5
40 19604589 Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiother Oncol 2009 Sep 2
41 20039079 The intravenous anesthetic propofol inhibits lipopolysaccharide-induced hypoxia-inducible factor 1 activation and suppresses the glucose metabolism in macrophages. J Anesth 2010 Feb 1
42 20133848 Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A 2010 Feb 2 7
43 20144215 Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol. Mol Cancer 2010 Feb 9 18
44 20145128 Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. Cancer Res 2010 Feb 15 1
45 20675437 Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation. Am J Physiol Lung Cell Mol Physiol 2010 Oct 2
46 20699381 A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism. Mol Cell Proteomics 2010 Dec 2
47 20723579 Adenosine regulates Sertoli cell function by activating AMPK. Mol Cell Endocrinol 2010 Dec 15 1
48 21332213 Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells. J Med Chem 2011 Mar 24 5
49 21356207 Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects. Exp Cell Res 2011 May 1 1
50 21723511 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab 2011 Jul 6 2