Niclosamide






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1 2128985 Control of Schistosoma mansoni in the Blue Nile Valley of western Ethiopia by mass chemotherapy and focal snail control: a primary health care experience. Trans R Soc Trop Med Hyg 1990 Nov-Dec 1
2 3509190 [Action of a molluscacide (Bayluscide-SRB) from the Dynatech R/D Company in lakes of northeastern Brazil--Sergipe, Brazil]. Mem Inst Oswaldo Cruz 1987 1
3 3704470 Trials on focal molluscicide application in larger irrigation canals and lakes in Mali. Trop Med Parasitol 1986 Mar 1
4 7386719 Phospholipase B levels in fecal pellets from mice infected with Trichinella spiralis, Hymenolepis nana, and Schistosoma mansoni. Am J Trop Med Hyg 1980 May 1
5 11124226 Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s. Drug Metab Dispos 2001 Jan 2
6 14557374 Generation and evaluation of a CYP2C9 heteroactivation pharmacophore. J Pharmacol Exp Ther 2003 Dec 1
7 15296091 Physical transformation of niclosamide solvates in pharmaceutical suspensions determined by DSC and TG analysis. Pharmazie 2004 Jul 2
8 18454287 A novel molluscicidal formulation of niclosamide. Parasitol Res 2008 Jul 1
9 19160421 The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells. J Cell Biochem 2009 Mar 1 2
10 19771169 Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. PLoS One 2009 Sep 22 1
11 19772353 The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Biochemistry 2009 Nov 3 10
12 20215516 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. Cancer Res 2010 Mar 15 1
13 21058733 Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro. Biochemistry 2010 Dec 14 1
14 21203451 Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition. PLoS One 2010 Dec 23 1
15 21531761 Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. Cancer Res 2011 Jun 15 7
16 21685359 Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. J Natl Cancer Inst 2011 Jul 6 3
17 21752808 Internal versus external determinants of Schistosoma japonicum transmission in irrigated agricultural villages. J R Soc Interface 2012 Feb 7 1
18 21871175 Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death. BMB Rep 2011 Aug 2
19 22171093 The antipsychotic drug loxapine is an opener of the sodium-activated potassium channel slack (Slo2.2). J Pharmacol Exp Ther 2012 Mar 3
20 22195040 Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway. PLoS One 2011 11
21 22237038 Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells. Chin J Cancer 2012 Apr 4
22 22474287 Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. J Biol Chem 2012 May 18 9
23 22799185 [Effect of snail control of niclosamide by soil mixing and spraying methods in high dam of terrace]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2012 Apr 2
24 22829072 Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production. Blood Cancer J 2011 Oct 1
25 23333246 Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells. Cell Signal 2013 Apr 1
26 23453073 Small molecule modulators of Wnt/β-catenin signaling. Bioorg Med Chem Lett 2013 Apr 1 2
27 23459613 Discovery of <i>O</i>-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett 2013 Feb 14 1
28 23894143 Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer. Mol Cancer Ther 2013 Oct 2
29 23908450 Anticancer effects of niclosamide in human glioblastoma. Clin Cancer Res 2013 Aug 1 3
30 23956140 CYP1A1 and Cnr nitroreductase bioactivated niclosamide in vitro. Mutagenesis 2013 Nov 6
31 24019973 Inhibition of STAT3 by niclosamide synergizes with erlotinib against head and neck cancer. PLoS One 2013 5
32 24273411 Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway. Onco Targets Ther 2013 3
33 24362463 Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer. Mol Cancer Ther 2014 Mar 4
34 24416452 The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. PLoS One 2014 3
35 24552774 Effect of niclosamide on basal-like breast cancers. Mol Cancer Ther 2014 Apr 6
36 24561310 Antihelminthic niclosamide modulates dendritic cells activation and function. Cell Immunol 2014 Mar-Apr 6
37 24732808 Multi-targeted therapy of cancer by niclosamide: A new application for an old drug. Cancer Lett 2014 Jul 10 4
38 24736023 Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer. Gynecol Oncol 2014 Jul 3
39 24740322 Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer. Clin Cancer Res 2014 Jun 15 3
40 24750999 Niclosamide enhances ROS-mediated cell death through c-Jun activation. Biomed Pharmacother 2014 Jun 7
41 24900231 Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. ACS Med Chem Lett 2010 Dec 9 2
42 24945434 STAT3 modulation to enhance motor neuron differentiation in human neural stem cells. PLoS One 2014 7
43 25093354 Niclosamide methanol solvate and niclosamide hydrate: structure, solvent inclusion mode and implications for properties. Acta Crystallogr C Struct Chem 2014 Aug 2
44 25174399 WNT7A/β-catenin signaling induces FGF1 and influences sensitivity to niclosamide in ovarian cancer. Oncogene 2015 Jun 8
45 25708600 Inhibitory effects of niclosamide on inflammation and migration of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Inflamm Res 2015 Apr 12
46 25970160 Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. Prostate 2015 Sep 5
47 26068521 Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1. Xenobiotica 2016 7
48 26116531 Niclosamide, an anti-helminthic molecule, downregulates the retroviral oncoprotein Tax and pro-survival Bcl-2 proteins in HTLV-1-transformed T lymphocytes. Biochem Biophys Res Commun 2015 Aug 14 2
49 26118906 The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets 2015 5
50 26186072 Niclosamide Analogs for Treatment of Ovarian Cancer. Int J Gynecol Cancer 2015 Oct 1