(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol


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133 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 71
2 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 38
3 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 34
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 25
5 target of rapamycin TOR_ARATH TOR Arabidopsis thaliana 841427 64 16
6 mechanistic target of rapamycin kinase MTOR_MOUSE Mtor Mus musculus 56717 1120 13
7 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 5
8 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 5
9 eukaryotic translation initiation factor 4E binding protein 1 4EBP1_HUMAN EIF4EBP1 Homo sapiens 1978 300 5
10 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 4
11 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 4
12 mechanistic target of rapamycin kinase MTOR_RAT Mtor Rattus norvegicus 56718 809 3
13 CREB regulated transcription coactivator 1 CRTC1_HUMAN CRTC1 Homo sapiens 23373 120 3
14 regulatory associated protein of MTOR complex 1 RPTOR_HUMAN RPTOR Homo sapiens 57521 98 3
15 taste 2 receptor member 63 pseudogene - TAS2R63P Homo sapiens 338413 60 2
16 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 2
17 YAK1-like protein 1 YAK1_ARATH YAK1 Arabidopsis thaliana 833590 6 2
18 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 2
19 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 2
20 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 2
21 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 2
22 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 2
23 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
24 ribosomal protein S6 kinase, polypeptide 1 KS6B1_MOUSE Rps6kb1 Mus musculus 72508 289 2
25 DNA damage inducible transcript 4 DDIT4_HUMAN DDIT4 Homo sapiens 54541 101 2
26 serum/glucocorticoid regulated kinase 1 SGK1_MOUSE Sgk1 Mus musculus 20393 142 2
27 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 2
28 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 2
29 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 2
30 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 2
31 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 1
32 NLR family pyrin domain containing 3 NLRP3_HUMAN NLRP3 Homo sapiens 114548 1179 1
33 ETS transcription factor ERG ERG_HUMAN ERG Homo sapiens 2078 1044 1
34 negative elongation factor complex member C/D NELFD_HUMAN NELFCD Homo sapiens 51497 992 1
35 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 1
36 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 1
37 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 1
38 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 1
39 glutamic--pyruvic transaminase ALAT1_HUMAN GPT Homo sapiens 2875 774 1
40 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 1
41 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 1
42 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 1
43 cyclin D1 CCND1_MOUSE Ccnd1 Mus musculus 12443 585 1
44 interleukin 2 IL2_MOUSE Il2 Mus musculus 16183 1527 1
45 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
46 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 1
47 ribosomal protein S6 kinase B1 KS6B1_RAT Rps6kb1 Rattus norvegicus 83840 301 1
48 proopiomelanocortin COLI_HUMAN POMC Homo sapiens 5443 2059 1
49 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 1
50 LIF interleukin 6 family cytokine LIF_HUMAN LIF Homo sapiens 3976 950 1