cucurbitacin I


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112 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 55
2 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 22
3 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 9
4 signal transducer and activator of transcription 3 STAT3_RAT Stat3 Rattus norvegicus 25125 689 7
5 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 5
6 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 4
7 Janus kinase 2 JAK2_RAT Jak2 Rattus norvegicus 24514 336 3
8 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
9 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 3
10 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 3
11 indoleamine 2,3-dioxygenase 1 I23O1_HUMAN IDO1 Homo sapiens 3620 790 2
12 Janus kinase 2 JAK2_MOUSE Jak2 Mus musculus 16452 466 2
13 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 2
14 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 2
15 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
16 prominin 1 PROM1_MOUSE Prom1 Mus musculus 19126 156 2
17 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 2
18 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2
19 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 2
20 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 2
21 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
22 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 2
23 cellular communication network factor 2 CCN2_HUMAN CCN2 Homo sapiens 1490 467 2
24 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 2
25 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 2
26 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 2
27 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 2
28 integrin subunit alpha X ITAX_HUMAN ITGAX Homo sapiens 3687 353 1
29 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
30 lysine acetyltransferase 2B KAT2B_HUMAN KAT2B Homo sapiens 8850 295 1
31 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 1
32 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 1
33 LIF interleukin 6 family cytokine LIF_HUMAN LIF Homo sapiens 3976 950 1
34 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 1
35 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 1
36 microtubule associated protein 1 light chain 3 alpha MLP3A_HUMAN MAP1LC3A Homo sapiens 84557 710 1
37 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 1
38 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 1
39 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 1
40 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 1
41 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 1
42 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 1
43 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 1
44 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 1
45 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 1
46 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 1
47 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 1
48 CD44 antigen CD44_MOUSE Cd44 Mus musculus 12505 468 1
49 cyclin D1 CCND1_MOUSE Ccnd1 Mus musculus 12443 585 1
50 Jun proto-oncogene, AP-1 transcription factor subunit JUN_HUMAN JUN Homo sapiens 3725 1260 1