prexasertib


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42 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 37
2 checkpoint kinase 1 CHK1_MOUSE Chek1 Mus musculus 12649 90 5
3 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 4
4 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 3
5 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 3
6 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 3
7 cyclin dependent kinase 2 CDK2_HUMAN CDK2 Homo sapiens 1017 1201 2
8 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 2
9 replication protein A2 RFA2_HUMAN RPA2 Homo sapiens 6118 52 2
10 jagged canonical Notch ligand 2 JAG2_HUMAN JAG2 Homo sapiens 3714 100 1
11 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 1
12 metallothionein 1E MT1E_HUMAN MT1E Homo sapiens 4493 133 1
13 salt inducible kinase 1 SIK1_HUMAN SIK1 Homo sapiens 150094 60 1
14 hes family bHLH transcription factor 1 HES1_HUMAN HES1 Homo sapiens 3280 192 1
15 delta like canonical Notch ligand 1 DLL1_HUMAN DLL1 Homo sapiens 28514 56 1
16 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 1
17 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 1
18 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
19 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 1
20 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 1
21 cyclin B1 CCNB1_HUMAN CCNB1 Homo sapiens 891 652 1
22 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 1
23 notch receptor 3 NOTC3_HUMAN NOTCH3 Homo sapiens 4854 150 1
24 cyclin E1 CCNE1_HUMAN CCNE1 Homo sapiens 898 140 1
25 mastermind like transcriptional coactivator 2 MAML2_HUMAN MAML2 Homo sapiens 84441 17 1
26 notch receptor 2 NOTC2_HUMAN NOTCH2 Homo sapiens 4853 119 1
27 jagged canonical Notch ligand 1 JAG1_HUMAN JAG1 Homo sapiens 182 199 1
28 S-phase kinase associated protein 2 SKP2_HUMAN SKP2 Homo sapiens 6502 235 1
29 notch receptor 1 NOTC1_HUMAN NOTCH1 Homo sapiens 4851 598 1
30 WEE1 G2 checkpoint kinase WEE1_HUMAN WEE1 Homo sapiens 7465 177 1
31 MRE11 homolog, double strand break repair nuclease MRE11_HUMAN MRE11 Homo sapiens 4361 104 1
32 eukaryotic translation initiation factor 4E binding protein 1 4EBP1_MOUSE Eif4ebp1 Mus musculus 13685 94 1
33 cell division cycle 25A MPIP1_HUMAN CDC25A Homo sapiens 993 220 1
34 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 1
35 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 1
36 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
37 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 1
38 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 1
39 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 1
40 BCL2-related ovarian killer BOK_MOUSE Bok Mus musculus 51800 54 1
41 proteasome 26S subunit, non-ATPase 1 PSMD1_HUMAN PSMD1 Homo sapiens 5707 302 1
42 megakaryocyte-associated tyrosine kinase MATK_HUMAN MATK Homo sapiens 4145 84 1