dactolisib


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267 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 301
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 106
3 mechanistic target of rapamycin kinase MTOR_MOUSE Mtor Mus musculus 56717 1120 36
4 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 21
5 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 17
6 eukaryotic translation initiation factor 4E binding protein 1 4EBP1_HUMAN EIF4EBP1 Homo sapiens 1978 300 15
7 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 15
8 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 13
9 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 12
10 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 10
11 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 10
12 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 10
13 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 9
14 mechanistic target of rapamycin kinase MTOR_RAT Mtor Rattus norvegicus 56718 809 8
15 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 8
16 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 7
17 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 7
18 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 7
19 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 7
20 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 7
21 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 6
22 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 6
23 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 6
24 insulin INS_HUMAN INS Homo sapiens 3630 7950 5
25 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 5
26 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 5
27 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 5
28 taste 2 receptor member 63 pseudogene - TAS2R63P Homo sapiens 338413 60 5
29 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 5
30 dynactin subunit 6 DCTN6_HUMAN DCTN6 Homo sapiens 10671 338 4
31 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 4
32 Kirsten rat sarcoma viral oncogene homolog RASK_MOUSE Kras Mus musculus 16653 464 4
33 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 4
34 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 4
35 autophagy related 5 ATG5_HUMAN ATG5 Homo sapiens 9474 397 3
36 S-phase kinase associated protein 2 SKP2_HUMAN SKP2 Homo sapiens 6502 235 3
37 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 3
38 CREB regulated transcription coactivator 1 CRTC1_HUMAN CRTC1 Homo sapiens 23373 120 3
39 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 3
40 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 3
41 glycogen synthase kinase 3 beta GSK3B_HUMAN GSK3B Homo sapiens 2932 1189 3
42 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 3
43 ribosomal protein S6 RS6_HUMAN RPS6 Homo sapiens 6194 149 3
44 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 3
45 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 2
46 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 2
47 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma PK3CG_HUMAN PIK3CG Homo sapiens 5294 232 2
48 phosphoinositide-3-kinase regulatory subunit 1 P85A_MOUSE Pik3r1 Mus musculus 18708 315 2
49 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 2
50 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 2