neratinib


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122 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 174
2 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 77
3 erb-b2 receptor tyrosine kinase 4 ERBB4_HUMAN ERBB4 Homo sapiens 2066 169 12
4 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 8
5 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 8
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 8
7 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 7
8 erb-b2 receptor tyrosine kinase 2 ERBB2_MOUSE Erbb2 Mus musculus 13866 567 7
9 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 6
10 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 6
11 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
12 nuclear receptor subfamily 4 group A member 1 NR4A1_HUMAN NR4A1 Homo sapiens 3164 657 6
13 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 5
14 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 5
15 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 5
16 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 4
17 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 4
18 tafazzin, phospholipid-lysophospholipid transacylase TAZ_HUMAN TAFAZZIN Homo sapiens 6901 297 4
19 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 4
20 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 4
21 eukaryotic translation initiation factor 2A EIF2A_HUMAN EIF2A Homo sapiens 83939 566 3
22 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 3
23 cathepsin B CATB_HUMAN CTSB Homo sapiens 1508 1121 3
24 histone deacetylase 9 HDAC9_HUMAN HDAC9 Homo sapiens 9734 707 3
25 autophagy related 5 ATG5_HUMAN ATG5 Homo sapiens 9474 397 3
26 unc-51 like autophagy activating kinase 1 ULK1_HUMAN ULK1 Homo sapiens 8408 234 3
27 large tumor suppressor kinase 1 LATS1_HUMAN LATS1 Homo sapiens 9113 70 3
28 macrophage stimulating 1 HGFL_HUMAN MST1 Homo sapiens 4485 148 3
29 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 3
30 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
31 p21 (RAC1) activated kinase 1 PAK1_HUMAN PAK1 Homo sapiens 5058 234 2
32 rubicon autophagy regulator RUBIC_HUMAN RUBCN Homo sapiens 9711 19 2
33 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2
34 CREB regulated transcription coactivator 1 CRTC1_HUMAN CRTC1 Homo sapiens 23373 120 2
35 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 2
36 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 2
37 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor MERL_HUMAN NF2 Homo sapiens 4771 212 2
38 epiregulin EREG_HUMAN EREG Homo sapiens 2069 498 2
39 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 2
40 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 2
41 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 2
42 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 2
43 vitamin K epoxide reductase complex subunit 1 VKOR1_HUMAN VKORC1 Homo sapiens 79001 133 2
44 hexokinase 1 HXK1_HUMAN HK1 Homo sapiens 3098 604 2
45 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
46 autophagy related 13 ATG13_HUMAN ATG13 Homo sapiens 9776 42 2
47 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 2
48 ornithine decarboxylase 1 DCOR_HUMAN ODC1 Homo sapiens 4953 714 2
49 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 2
50 C-C motif chemokine ligand 4 CCL4_HUMAN CCL4 Homo sapiens 6351 996 1