Erlotinib Hydrochloride


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783 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2428
2 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 131
3 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 103
4 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 55
5 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 43
6 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 41
7 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 37
8 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 33
9 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 26
10 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 24
11 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 23
12 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 23
13 epidermal growth factor receptor Q9QX70_RAT Egfr Rattus norvegicus 24329 495 23
14 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 23
15 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 22
16 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 22
17 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 20
18 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 18
19 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 17
20 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 17
21 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 15
22 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 14
23 TXK tyrosine kinase TXK_HUMAN TXK Homo sapiens 7294 195 13
24 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 13
25 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 12
26 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 12
27 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 10
28 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 10
29 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 10
30 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 10
31 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 10
32 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 10
33 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 9
34 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 9
35 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 9
36 cellular inhibitor of PP2A CIP2A_HUMAN CIP2A Homo sapiens 57650 132 9
37 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 9
38 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 8
39 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 8
40 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 8
41 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 8
42 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 8
43 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 8
44 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 8
45 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 7
46 cytochrome P450 family 1 subfamily A member 2 CP1A2_HUMAN CYP1A2 Homo sapiens 1544 1532 7
47 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 7
48 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 7
49 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 7
50 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 7