Gefitinib


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1108 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2974
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 219
3 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 161
4 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 101
5 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 98
6 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 55
7 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 52
8 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 44
9 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 43
10 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 42
11 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 37
12 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 37
13 epidermal growth factor receptor Q9QX70_RAT Egfr Rattus norvegicus 24329 495 36
14 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 36
15 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 35
16 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 35
17 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 32
18 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 28
19 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 28
20 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 25
21 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 24
22 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 23
23 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 23
24 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 23
25 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 21
26 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 21
27 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 19
28 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 19
29 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 19
30 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 19
31 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 18
32 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 18
33 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 18
34 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 17
35 amphiregulin AREG_HUMAN AREG Homo sapiens 374 200 16
36 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 15
37 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 15
38 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 15
39 CEA cell adhesion molecule 3 CEAM3_HUMAN CEACAM3 Homo sapiens 1084 1053 14
40 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 14
41 transforming growth factor alpha TGFA_HUMAN TGFA Homo sapiens 7039 974 13
42 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 12
43 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 12
44 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 12
45 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 11
46 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 11
47 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 11
48 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 11
49 prominin 1 PROM1_HUMAN PROM1 Homo sapiens 8842 522 11
50 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 10