Diphosphonates


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481 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 farnesyl diphosphate synthase FPPS_HUMAN FDPS Homo sapiens 2224 223 109
2 parathyroid hormone PTHY_HUMAN PTH Homo sapiens 5741 1284 37
3 TNF superfamily member 11 TNF11_HUMAN TNFSF11 Homo sapiens 8600 766 34
4 cytochrome P450 family 27 subfamily A member 1 CP27A_HUMAN CYP27A1 Homo sapiens 1593 433 24
5 TNF receptor superfamily member 11b TR11B_HUMAN TNFRSF11B Homo sapiens 4982 502 23
6 alkaline phosphatase, placental PPB1_HUMAN ALPP Homo sapiens 250 1677 20
7 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 18
8 bone gamma-carboxyglutamate protein OSTCN_HUMAN BGLAP Homo sapiens 632 987 18
9 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 16
10 geranylgeranyl diphosphate synthase 1 GGPPS_HUMAN GGPS1 Homo sapiens 9453 49 15
11 bone morphogenetic protein 2 BMP2_HUMAN BMP2 Homo sapiens 650 860 14
12 parathyroid hormone like hormone PTHR_HUMAN PTHLH Homo sapiens 5744 406 14
13 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 12
14 tumor necrosis factor (ligand) superfamily, member 11 TNF11_MOUSE Tnfsf11 Mus musculus 21943 974 11
15 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) TR11B_MOUSE Tnfrsf11b Mus musculus 18383 309 10
16 hedgehog interacting protein HHIP_HUMAN HHIP Homo sapiens 64399 253 10
17 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 10
18 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 8
19 cytochrome P450 family 2 subfamily C member 8 CP2C8_HUMAN CYP2C8 Homo sapiens 1558 590 8
20 gonadotropin releasing hormone 1 GON1_HUMAN GNRH1 Homo sapiens 2796 1184 8
21 acid phosphatase 5, tartrate resistant PPA5_HUMAN ACP5 Homo sapiens 54 93 8
22 parathyroid hormone PTHY_RAT Pth Rattus norvegicus 24694 652 7
23 ATHS - ATHS Homo sapiens 470 457 7
24 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 7
25 phorbol-12-myristate-13-acetate-induced protein 1 APR_HUMAN PMAIP1 Homo sapiens 5366 357 6
26 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 6
27 cathepsin K CATK_HUMAN CTSK Homo sapiens 1513 362 6
28 dickkopf WNT signaling pathway inhibitor 1 DKK1_HUMAN DKK1 Homo sapiens 22943 264 6
29 fibroblast growth factor 2 FGF2_HUMAN FGF2 Homo sapiens 2247 1502 6
30 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 6
31 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 6
32 farnesyl diphosphate synthetase FPPS_MOUSE Fdps Mus musculus 110196 34 6
33 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 6
34 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 6
35 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 6
36 PDB1 - PDB1 Homo sapiens 5131 65 5
37 TNF superfamily member 11 TNF11_RAT Tnfsf11 Rattus norvegicus 117516 336 5
38 matrix metallopeptidase 1 MMP1_HUMAN MMP1 Homo sapiens 4312 1304 5
39 calcitonin related polypeptide alpha CALCA_HUMAN CALCA Homo sapiens 796 784 5
40 farnesyl diphosphate synthase FPPS_RAT Fdps Rattus norvegicus 83791 49 5
41 TNF receptor superfamily member 11B TR11B_RAT Tnfrsf11b Rattus norvegicus 25341 254 5
42 gap junction protein, alpha 1 CXA1_MOUSE Gja1 Mus musculus 14609 338 4
43 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 4
44 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 4
45 cytochrome P450 family 19 subfamily A member 1 CP19A_HUMAN CYP19A1 Homo sapiens 1588 827 4
46 NUMB endocytic adaptor protein NUMB_HUMAN NUMB Homo sapiens 8650 67 4
47 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 4
48 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 4
49 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 4
50 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 4