1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione


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310 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 31
2 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 25
3 protein kinase, DNA-activated, catalytic subunit PRKDC_HUMAN PRKDC Homo sapiens 5591 418 25
4 tumor protein p53 binding protein 1 TP53B_HUMAN TP53BP1 Homo sapiens 7158 156 18
5 MRE11 homolog, double strand break repair nuclease MRE11_HUMAN MRE11 Homo sapiens 4361 104 13
6 nibrin NBN_HUMAN NBN Homo sapiens 4683 703 13
7 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 12
8 RB binding protein 8, endonuclease CTIP_HUMAN RBBP8 Homo sapiens 5932 60 12
9 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 12
10 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 11
11 MRX complex nuclease subunit MRE11_YEAST MRE11 Saccharomyces cerevisiae S288C 855264 35 9
12 mediator of DNA damage checkpoint 1 MDC1_HUMAN MDC1 Homo sapiens 9656 57 9
13 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 8
14 X-ray repair cross complementing 5 XRCC5_HUMAN XRCC5 Homo sapiens 7520 112 6
15 RAD50 double strand break repair protein RAD50_HUMAN RAD50 Homo sapiens 10111 70 6
16 X-ray repair cross complementing 6 XRCC6_HUMAN XRCC6 Homo sapiens 2547 113 6
17 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
18 H2A.X variant histone H2AX_MOUSE H2ax Mus musculus 15270 247 5
19 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 5
20 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 4
21 SPO11 initiator of meiotic double stranded breaks SPO11_MOUSE Spo11 Mus musculus 26972 13 4
22 recombinase RAD51 RAD51_YEAST RAD51 Saccharomyces cerevisiae S288C 856831 54 4
23 DNA topoisomerase (ATP-hydrolyzing) SPO11_YEAST SPO11 Saccharomyces cerevisiae S288C 856364 14 4
24 X-ray repair cross complementing 4 XRCC4_HUMAN XRCC4 Homo sapiens 7518 66 4
25 lysine acetyltransferase 5 KAT5_HUMAN KAT5 Homo sapiens 10524 97 4
26 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 4
27 partner and localizer of BRCA2 PALB2_HUMAN PALB2 Homo sapiens 79728 35 4
28 RecQ like helicase 4 RECQ4_HUMAN RECQL4 Homo sapiens 9401 35 4
29 exonuclease 1 EXO1_HUMAN EXO1 Homo sapiens 9156 169 3
30 replication timing regulatory factor 1 RIF1_HUMAN RIF1 Homo sapiens 55183 63 3
31 CREB binding protein CBP_HUMAN CREBBP Homo sapiens 1387 584 3
32 discs large MAGUK scaffold protein 3 DLG3_HUMAN DLG3 Homo sapiens 1741 32 3
33 SPO11 initiator of meiotic double stranded breaks SPO11_HUMAN SPO11 Homo sapiens 23626 7 3
34 ssDNA endodeoxyribonuclease SAE2 COM1_YEAST SAE2 Saccharomyces cerevisiae S288C 852700 15 3
35 Meiotic recombination protein spo-11;TP6A_N domain-containing protein SPO11_CAEEL spo-11 Caenorhabditis elegans 191771 3 3
36 RAD18 E3 ubiquitin protein ligase RAD18_HUMAN RAD18 Homo sapiens 56852 51 3
37 ring finger protein 4 RNF4_HUMAN RNF4 Homo sapiens 6047 30 3
38 SET domain and mariner transposase fusion gene SETMR_HUMAN SETMAR Homo sapiens 6419 20 3
39 WRN RecQ like helicase WRN_HUMAN WRN Homo sapiens 7486 126 3
40 RAD52 homolog, DNA repair protein RAD52_HUMAN RAD52 Homo sapiens 5893 49 3
41 recombination activating 1 RAG1_HUMAN RAG1 Homo sapiens 5896 91 3
42 chromodomain Y like CDYL_HUMAN CDYL Homo sapiens 9425 13 2
43 ring finger protein 8 RNF8_HUMAN RNF8 Homo sapiens 9025 33 2
44 Pch2p PCH2_YEAST PCH2 Saccharomyces cerevisiae S288C 852484 9 2
45 MRE11A homolog A, double strand break repair nuclease MRE11_MOUSE Mre11a Mus musculus 17535 17 2
46 retinoblastoma binding protein 8, endonuclease CTIP_MOUSE Rbbp8 Mus musculus 225182 5 2
47 recombinase DMC1 DMC1_YEAST DMC1 Saccharomyces cerevisiae S288C 856926 10 2
48 ligase IV, DNA, ATP-dependent DNLI4_MOUSE Lig4 Mus musculus 319583 10 2
49 ATP-dependent DNA helicase SGS1 SGS1_YEAST SGS1 Saccharomyces cerevisiae S288C 855228 36 2
50 Nej1p NEJ1_YEAST NEJ1 Saccharomyces cerevisiae S288C 850970 4 2