Pub. Date : 1996 Jul
PMID : 8765983
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Insulin-like growth factor I stimulated dose-dependently the incorporation of [3H]thymidine, maximally at 100 ng/ml, which corresponded to an increase of DNA content by 60% after 6 days. | Tritium | insulin like growth factor 1 | Sus scrofa |
| 2 | Stimulation of iodide transport by IGF-I was modest after 2 days and pronounced after 6 days. | Iodides | insulin like growth factor 1 | Sus scrofa |
| 3 | During these conditions, the mitogenic effect of IGF-I is partially inhibited by TSH, which has no growth-promoting action on its own. | Thyrotropin | insulin like growth factor 1 | Sus scrofa |
| 4 | The transepithelial transport of iodide and bulk electrolytes is altered by IGF-I without affecting the epithelial barrier function. | Iodides | insulin like growth factor 1 | Sus scrofa |
| 5 | Specifically, IGF-I up-regulates the activity of the basolateral iodide pump and increases the iodide permeability of the apical plasma membrane. | Iodides | insulin like growth factor 1 | Sus scrofa |
| 6 | Specifically, IGF-I up-regulates the activity of the basolateral iodide pump and increases the iodide permeability of the apical plasma membrane. | Iodides | insulin like growth factor 1 | Sus scrofa |
| 7 | The action of IGF-I on iodide transport is independent of, although synergistic with, that of TSH. | Iodides | insulin like growth factor 1 | Sus scrofa |