Pub. Date : 1994 Jan 17
PMID : 7910680
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nicotine-induced regulation of tyrosine hydroxylase activity in adrenal gland of transgenic mouse carrying human tyrosine hydroxylase gene. | Nicotine | tyrosine hydroxylase | Mus musculus |
2 | We investigated the effect of subcutaneous injection of nicotine on in vitro tyrosine hydroxylase (TH) activity in adrenal gland and brain of the transgenic mice carrying an 11-kb fragment containing the entire human TH gene. | Nicotine | tyrosine hydroxylase | Mus musculus |
3 | We investigated the effect of subcutaneous injection of nicotine on in vitro tyrosine hydroxylase (TH) activity in adrenal gland and brain of the transgenic mice carrying an 11-kb fragment containing the entire human TH gene. | Nicotine | tyrosine hydroxylase | Mus musculus |
4 | Injection of 5 mg nicotine/kg (as free base) for 3 days caused a statistically significant increase in vitro TH activity in the adrenal gland, whereas brain TH activity was not affected at all. | Nicotine | tyrosine hydroxylase | Mus musculus |
5 | This observation might indicate the possibility that the machinery used by nicotine in regulating the properties or expression of TH in the adrenal gland should be similar between transgenic and non-transgenic mice. | Nicotine | tyrosine hydroxylase | Mus musculus |