Title : Bovine serum albumin--haloperidol as a tool for the study of dopaminergic transmission: behavioural and neurochemical effects following a single injection in the nucleus accumbens.

Pub. Date : 1987 Jan 12

PMID : 3796216






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bovine serum albumin haloperidol (BSA-Hal) is a macromolecular complex with 14 molecules of haloperidol immobilized on the BSA protein backbone. Haloperidol histidine ammonia-lyase Homo sapiens
2 Bovine serum albumin haloperidol (BSA-Hal) is a macromolecular complex with 14 molecules of haloperidol immobilized on the BSA protein backbone. Haloperidol histidine ammonia-lyase Homo sapiens
3 The results indicate that the specific and long lasting blockade of dopamine receptors by bilateral injection of BSA-Hal in the n.Acc (1.6 micrograms/2 microliters) induced deficits in spontaneous alternation in a Y-maze on the 2nd and 5th days after the injection but not on the 11th day of the experiment, impaired acquisition but not retention in a radial 8-arm maze, increased latency to escape during learning in the place navigation task. 1-aminocyclopropane-1-carboxylic acid histidine ammonia-lyase Homo sapiens