Title : Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

Pub. Date : 1987 May 15

PMID : 3592665






1 Functional Relationships(s)
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1 The selective expression of cytochrome P-450h in mature male rats largely accounted for the male-specific, postpubertal increase in the rate of testosterone 2 alpha-, 16 alpha, and 17-oxidation, whereas the selective repression of cytochrome P-450p in female rats accounted for the female-specific, postpubertal decline in testosterone 2 beta-, 6 beta-, 15 beta-, and 18-hydroxylase activity. Testosterone cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus