Pub. Date : 2020 Jul 29
PMID : 32751124
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | After four weeks in culture, 3D differentiated constructs and 2D monolayer cultures treated with Icariin or Purmorphamine showed increased mineralization, ALP activity, and the gene expression of bone formation markers (BGLAP, SSP1, and COL1A1), signaling molecules (MAPK1, WNT1, and AKT1), and transcription factors (RUNX2 and GLI1) that regulate osteogenic differentiation relative to untreated. | icariin | SUMO specific peptidase 6 | Homo sapiens |
| 2 | After four weeks in culture, 3D differentiated constructs and 2D monolayer cultures treated with Icariin or Purmorphamine showed increased mineralization, ALP activity, and the gene expression of bone formation markers (BGLAP, SSP1, and COL1A1), signaling molecules (MAPK1, WNT1, and AKT1), and transcription factors (RUNX2 and GLI1) that regulate osteogenic differentiation relative to untreated. | purmorphamine | SUMO specific peptidase 6 | Homo sapiens |