Pub. Date : 2020 May
PMID : 32385422
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SCAP induces translocation of SREBP from the endoplasmic reticulum to the Golgi apparatus, allowing it to regulate cellular triglyceride and cholesterol levels. | Triglycerides | SREBF chaperone | Mus musculus |
| 2 | SCAP induces translocation of SREBP from the endoplasmic reticulum to the Golgi apparatus, allowing it to regulate cellular triglyceride and cholesterol levels. | Cholesterol | SREBF chaperone | Mus musculus |
| 3 | Previous studies have shown that suppression of SREBP activation in SCAP conditional knockout mice reduced the accumulation of intracellular triglycerides, which eventually causes the development of metabolic diseases such as atherosclerosis, diabetes, hepatic steatosis, and insulin resistance. | Triglycerides | SREBF chaperone | Mus musculus |